selected publications
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academic article
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Li ANelson SRRahmanseresht SBraet FCornachione ASPrevis SBO’Leary TSMcNamara JWRassier DESadayappan SPrevis MJWarshaw DM. Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems.
Proceedings of the National Academy of Sciences of USA.
116:21882-21892.
2019
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Ge ZLi AMcNamara Jdos Remedios CLal S. Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies.
Heart Failure Reviews.
24:743-758.
2019
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Papadaki MHolewinski RJPrevis SBMartin TGStachowski MJLi ABlair CAMoravec CSVan Eyk JECampbell KSWarshaw DMKirk JA. Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.
JCI insight.
3.
2018
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dos Remedios CGLi ALal S. Non-sarcomeric causes of heart failure: a Sydney Heart Bank perspective.
Biophysical Reviews.
10:949-954.
2018
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Kagemoto TOyama KYamane MTsukamoto SKobirumaki-Shimozawa FLi ADos Remedios CFukuda NIshiwata S. Sarcomeric Auto-Oscillations in Single Myofibrils From the Heart of Patients With Dilated Cardiomyopathy.
Circulation: Heart Failure.
11.
2018
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Lin BLLi AMun JYPrevis MJPrevis SBCampbell SGdos Remedios CGTombe PDPCraig RWarshaw DMSadayappan S. Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner.
Scientific Reports.
8.
2018
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Vikhorev PGSmoktunowicz NMunster ABCopeland OKostin SMontgiraud CMesser AEToliat MRLi Ados Remedios CGLal SBlair CACampbell KSGuglin MRichter MKnöll RMarston SB. Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.
Scientific Reports.
7.
2017
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Mamidi RLi JGresham KSVerma SDoh CYLi ALal Sdos Remedios CGStelzer JE. Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium.
Circulation: Heart Failure.
10.
2017
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Crossman DJShen XJüllig MMunro MHou YMiddleditch MShrestha DLi ALal Sdos Remedios CGBaddeley DRuygrok PNSoeller C. Increased collagen within the transverse tubules in human heart failure.
Cardiovascular Research.
113:879-891.
2017
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McNamara JWLi ALal SBos JMHarris SPVan Der Velden JAckerman MJCooke RDos Remedios CG. MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy.
PLoS ONE.
12.
2017
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dos Remedios CGLal SPLi AMcNamara JKeogh AMacdonald PSCooke REhler EKnöll RMarston SBStelzer JGranzier HBezzina Cvan Dijk SDe Man FStienen GJMOdeberg JPontén FLinke Wvan der Velden J. The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.
Biophysical Reviews.
9:431-441.
2017
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McNamara JWLi ASmith NJLal SGraham RMKooiker KBvan Dijk SJRemedios CGDHarris SPCooke R. Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes.
Journal of Molecular and Cellular Cardiology.
94:65-71.
2016
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Lin ZGuo HCao YZohrabian SZhou PMa QVanDusen NGuo YZhang JStevens SMLiang FQuan Qvan Gorp PRLi Ados Remedios CHe ABezzerides VJPu WT. Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.
Developmental Cell.
39:466-479.
2016
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Lal SNguyen LTezone RPonten FOdeberg JLi Ados Remedios C. Tissue microarray profiling in human heart failure.
Proteomics.
16:2319-2326.
2016
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Lal SLi AAllen DAllen PDBannon PCartmill TCooke RFarnsworth AKeogh Ados Remedios C. Best practice BioBanking of human heart tissue.
Biophysical Reviews.
7:399-406.
2015
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Mamidi RGresham KSLi Ados Remedios CGStelzer JE. Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C.
Journal of Molecular and Cellular Cardiology.
85:262-272.
2015
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Kagemoto TLi Ados Remedios CIshiwata S. Spontaneous oscillatory contraction (SPOC) in cardiomyocytes.
Biophysical Reviews.
7:15-24.
2015
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McNamara JWLi Ados Remedios CGCooke R. The role of super-relaxed myosin in skeletal and cardiac muscle.
Biophysical Reviews.
7:5-14.
2015
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Li ABos JMAckerman MJBraet FKekic MIshiwata Sdos Remedios CG. Depressed Contractility at Low-Load Spontaneous Oscillatory Contractions in Human Hypertrophic Cardiomyopathy with MYBPC3 Mutations.
Biophysical Journal.
106:347a-348a.
2014
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Midde KRich RMarandos PFudala RLi AGryczynski IBorejdo J. Comparison of Orientation and Rotational Motion of Skeletal Muscle Cross-bridges Containing Phosphorylated and Dephosphorylated Myosin Regulatory Light Chain.
Journal of Biological Chemistry.
288:7012-7023.
2013
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Li AEstigoy CRaftery MCameron DOdeberg JPontén FLal Sdos Remedios CG. Heart research advances using database search engines, Human Protein Atlas and the Sydney Heart Bank.
Heart Lung and Circulation.
22:819-826.
2013
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Li APonten Fdos Remedios CG. The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development.
Proteomics.
12:203-225.
2012
Full text if available
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Li ANelson SRRahmanseresht SBraet FCornachione ASPrevis SBO’Leary TSMcNamara JWRassier DESadayappan SPrevis MJWarshaw DM. Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems.
Proceedings of the National Academy of Sciences of USA.
116:21882-21892.
2019
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comment
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Li ALal Sdos Remedios CG. A step towards understanding the molecular nature of human heart failure: advances using the Sydney Heart Bank collection.
Biophysical Reviews.
241-244.
2019
Full text if available
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Li ALal Sdos Remedios CG. A step towards understanding the molecular nature of human heart failure: advances using the Sydney Heart Bank collection.
Biophysical Reviews.
241-244.
2019
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conference paper
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Nelson SRLi AKennedy GBeck-Previs SWarshaw DM. The Skeletal Muscle Super Relaxed State (SRX) is Localized to the C-Zone.
Biophysical Journal.
177a-177a.
2019
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Papadaki MHolewisnki RPrevis SMartin TStachowski MLi ABlair CCampbell KChristine MVan Eyk JAubert VWarshaw DKirk J. Diabetes with Heart Failure Increases Methylglyoxal Modifications in the Sarcomere Which Inhibit Function.
Biophysical Journal.
114a-114a.
2019
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Vikhorev PGLi ALal Sdos Remedios CGMarston SB. Effect of Truncated Mutations in the Titin Gene on Cardiac Function.
Biophysical Journal.
498a-498a.
2018
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Nguyen LMcNamara JDos Remedios CLi ALal S. Increased Phosphorylation of Cardiac Myosin Binding Protein C and Increased Expression of Troponin I in Normal Human Ageing.
Biophysical Journal.
557a-557a.
2017
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Li ANelson SLee KPrevis SBrack KPrevis MGovindan SSadayappan SCraig RWarshaw D. Skeletal Myosin-Binding Protein C Modulates Actomyosin Contractility in an Isoform-Dependent Manner.
Biophysical Journal.
117a-117a.
2017
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McNamara JWLi ALal SBos JMAckerman MJdos Remedios CGHarris SPCooke R. Regulation of the Super-Relaxed State of Myosin by Cardiac Myosin Binding Protein-C.
Biophysical Journal.
293a-293a.
2016
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Li ABeck Previs SPrevis MLin Bdos Remedios CCraig RSadayappan SWarshaw D. Skeletal Myosin Binding Protein-C Isoforms Modulate Actomyosin Contractility and are Regulated by Phosphorylation.
Biophysical Journal.
421a-421a.
2015
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Li AKing DBos MKable EMacdonald PBraet FHambly BIshiwata SAckerman MKekic MRemedios CD. 2SDP-04 The nature of myocardial heart failure : Are hypertrophic cardiomyopathies all the same?(2SDP ASB-BSJ Bilateral Symposium 2013,Symposium,The 51th Annual Meeting of the Biophysical Society of Japan).
Seibutsu Butsuri.
S99-S99.
2013
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Li AKing DBraet FIshiwata SRemedios CGDHarris SP. A New Way to Examine the Function of Mutant MYBPC3 Expression in Cardiomyocytes of Mice.
Biophysical Journal.
309a-309a.
2013
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Midde KRich RFudala RLi AGryczynski IBorejdo J. Relaxed Skeletal Muscle Crossbridges Containing Dephosphorylated Regulatory Light Chain are Better Oriented Than Phosphorylated Ones.
Biophysical Journal.
309a-309a.
2013
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Li AWolfe JEKable EBraet FKing DAKagemoto TMacdonald PSIshiwata Sdos Remedios CG. Heart of the Matter: Assessing Human Cardiomyopathies with Spontaneous Oscillatory Contractions (SPOC).
Biophysical Journal.
353a-353a.
2012
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Li AKing DKable EBraet FKagemoto TMacDonand PIshiwata Sdos Remedios C. Spontaneous Oscillatory Contractions (SPOC): Assessing the Contractility of Human Familial Cardiomyopathies.
Heart Lung and Circulation.
S64-S64.
2012
Full text if available
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Nelson SRLi AKennedy GBeck-Previs SWarshaw DM. The Skeletal Muscle Super Relaxed State (SRX) is Localized to the C-Zone.
Biophysical Journal.
177a-177a.
2019
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editorial article
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dos Remedios CGLi A. Editorial for issue #1 2018.
Biophysical Reviews.
10:1-2.
2018
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Li Ados Remedios C. Special issue on titin and its binding proteins in striated muscle.
Biophysical Reviews.
9:177-178.
2017
Full text if available
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dos Remedios CGLi A. Editorial for issue #1 2018.
Biophysical Reviews.
10:1-2.
2018
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erratum
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Vikhorev PGSmoktunowicz NMunster ABCopeland ONKostin SMontgiraud CMesser AEToliat MRLi Ados Remedios CGLal SBlair CACampbell KSGuglin MRichter MKnöll RMarston SB. Author Correction: Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.
Scientific Reports.
14485.
2018
Full text if available -
dos Remedios CGLal SPLi AMcNamara JKeogh AMacdonald PSCooke REhler EKnöll RMarston SBStelzer JGranzier HBezzina Cvan Dijk SDe Man FStienen GJMOdeberg JPontén FLinke WAvan der Velden J. Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.
Biophysical Reviews.
941-941.
2018
Full text if available
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Vikhorev PGSmoktunowicz NMunster ABCopeland ONKostin SMontgiraud CMesser AEToliat MRLi Ados Remedios CGLal SBlair CACampbell KSGuglin MRichter MKnöll RMarston SB. Author Correction: Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.
Scientific Reports.
14485.
2018
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letter
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Li A. Trials and tribulations of an early career academic pathway after returning to Australia: reflections from an early career investigator.
Biophysical Reviews.
131-134.
2019
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Lal SLi Ados Remedios C. Limitations in Translating Animal Studies to Humans in Cardiovascular Disease.
Journal of Cardiovascular Translational Research.
165-166.
2016
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Li A. Trials and tribulations of an early career academic pathway after returning to Australia: reflections from an early career investigator.
Biophysical Reviews.
131-134.
2019
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other publication
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Li Ados Remedios CG. Special Issue on human heart failure.
Biophysical Reviews.
1-3.
2015
Full text if available
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Li Ados Remedios CG. Special Issue on human heart failure.
Biophysical Reviews.
1-3.
2015