selected publications
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academic article
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Barrett TJDistel EMurphy AJHu JGarshick MSOgando YLiu JVaisar THeinecke JWBerger JSGoldberg IJFisher EA. Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation.
Circulation.
140:1170-1184.
2019
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De Souza DPAchuthan ALee MKBinger KJLee MCDavidson STull DLMcConville MJCook ADMurphy AJHamilton JAFleetwood AJ. Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages.
Journal of Clinical Investigation.
129:4239-4244.
2019
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Qin CXRosli SDeo MCao NWalsh JTate MAlexander AEDonner DHorlock DLi RKiriazis HLee MKSBourke JEYang YMurphy AJDu X-JGao XMRitchie RH. Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac2-26, Against Myocardial Infarction.
Frontiers in Pharmacology.
10.
2019
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Al-Sharea ALee MKSWhillas AMichell DLShihata WANicholls AJCooney ODKraakman MJVeiga CBJefferis A-MJackson KNagareddy PRLambert GWong CHYAndrews KLHead GAChin-Dusting JMurphy AJ. Chronic sympathetic driven hypertension promotes atherosclerosis by enhancing hematopoiesis.
Haematologica: the hematology journal.
104:456-467.
2019
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Khan SIShihata WAAndrews KLLee MKSMoore X-LJefferis A-MVinh AGaspari TDragoljevic DJennings GLMurphy AJChin-Dusting JPF. Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat.
The FASEB Journal.
33:1510-1521.
2019
Full text if available -
Mukhamedova NHoang ADragoljevic DDubrovsky LPushkarsky TLow HDitiatkovski MFu YOhkawa RMeikle PJHorvath ABrichacek BMiller YIMurphy ABukrinsky MSviridov D. Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.
PLoS Pathogens.
15.
2019
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Pernes GFlynn MCLancaster GIMurphy AJ. Fat for fuel: lipid metabolism in haematopoiesis.
Clinical and Translational Immunology.
8:1-16.
2019
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Lee MKSAl-Sharea AShihata WAVeiga CBCooney ODFleetwood AJFlynn MCClaeson EPalmer CSLancaster GIHenstridge DCHamilton JAMurphy AJ. Glycolysis is required for LPS-induced activation and adhesion of human CD14+ CD16− monocytes.
Frontiers in Immunology.
10:1-10.
2019
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K Chanthira Morgan PFang LLancaster GIMurphy AJ. Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases.
Journal of Lipid Research.
2019
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McKenzie MDGhisi MOxley EPNgo SCimmino LEsnault CLiu RSalmon JMBell CCAhmed NErlichster MWitkowski MTLiu GJChopin MDakic ASimankowicz EPomilio GVu TKrsmanovic PSu STian LBaldwin TMZalcenstein DADiRago LWang SMetcalf DJohnstone RWCroker BALancaster GIMurphy AJNaik SHNutt SLPospisil VSchroeder TWall MDawson MAWei AHde Thé HRitchie MEZuber JDickins RA. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.
Cell Stem Cell.
25:258-272.e9.
2019
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Flynn MCPernes GLee MKSNagareddy PRMurphy AJ. Monocytes, macrophages, and metabolic disease in atherosclerosis.
Frontiers in Pharmacology.
10.
2019
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Cartland SPGenner SWMartínez GJRobertson SKockx MLin RCO'Sullivan JFKoay YCManuneedhi Cholan PKebede MAMurphy AJMasters SBennett MRJessup WKritharides LGeczy CPatel SKavurma MM. TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis.
iScience.
12:41-52.
2019
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Al-Sharea ALee MKSPurton LEHawkins EDMurphy AJ. The haematopoietic stem cell niche: A new player in cardiovascular disease?.
Cardiovascular Research.
115:277-291.
2019
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Vanags LZTan JTMGalougahi KKSchaefer AWise SGMurphy AAli ZABursill CA. Apolipoprotein A-I Reduces In-Stent Restenosis and Platelet Activation and Alters Neointimal Cellular Phenotype.
JACC: Basic to Translational Science.
3:200-209.
2018
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Ivanov SMerlin JLee MKSMurphy AJGuinamard RR. Biology and function of adipose tissue macrophages, dendritic cells and B cells.
Atherosclerosis.
271:102-110.
2018
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Dragoljevic DKraakman MJNagareddy PRNgo DShihata WKammoun HLWhillas ALee MKSAl-Sharea APernes GFlynn MCLancaster GIFebbraio MAChin-Dusting JHanaoka BYWicks IPMurphy AJ. Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.
European Heart Journal.
39:2158-2167.
2018
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Dragoljevic DWesterterp MVeiga CBNagareddy PMurphy AJ. Disordered haematopoiesis and cardiovascular disease: A focus on myelopoiesis.
Clinical Science.
132:1889-1899.
2018
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Lancaster GILangley KGBerglund NAKammoun HLReibe SEstevez EWeir JMellett NAPernes GConway JRWLee MKSTimpson PMurphy AJMasters SLGerondakis SBartonicek NKaczorowski DCDinger MEMeikle PJBond PJFebbraio MA. Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.
Cell Metabolism.
27:1096-1110.e5.
2018
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Lee MKSAl-Sharea ADragoljevic DMurphy AJ. Hand of FATe: Lipid metabolism in hematopoietic stem cells.
Current Opinion in Lipidology.
29:240-245.
2018
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Nagareddy PRNoothi SKFlynn MCMurphy AJ. It's reticulated: the liver at the heart of atherosclerosis.
Journal of Endocrinology.
238:R1-R11.
2018
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Kraakman MJKammoun HLDragoljevic DAl-Sharea ALee MKSFlynn MCStolz CJGuirguis AALancaster GIChin-Dusting JCurtis DJMurphy AJ. Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.
Haematologica: the hematology journal.
103:597-606.
2018
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Huynh KPernes GMellett NMeikle PMurphy ALancaster G. Lipidomic Profiling of Murine Macrophages Treated with Fatty Acids of Varying Chain Length and Saturation Status.
Metabolites.
8:1-17.
2018
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Chang CLGarcia-Arcos INyrén ROlivecrona GKim JYHu YAgrawal RRMurphy AJGoldberg IJDeckelbaum RJ. Lipoprotein Lipase Deficiency Impairs Bone Marrow Myelopoiesis and Reduces Circulating Monocyte Levels.
Arteriosclerosis, Thrombosis and Vascular Biology.
38:509-519.
2018
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Al-Sharea AMurphy AJHuggins LAHu YGoldberg IJNagareddy PR. SGLT2 inhibition reduces atherosclerosis by enhancing lipoprotein clearance in Ldlr −/− type 1 diabetic mice.
Atherosclerosis.
271:166-176.
2018
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Khan SIAndrews KLJackson KLMemon BJefferis A-MLee MKSDiep HWei ZDrummond GRHead GAJennings GLMurphy AJVinh ASampson AKChin-Dusting JPF. Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat..
The FASEB Journal.
32:2747-2756.
2018
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Fang LMurphy AJDart AM. A clinical perspective of anti-fibrotic therapies for cardiovascular disease.
Frontiers in Pharmacology.
8.
2017
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Masson JJRMurphy AJLee MKSOstrowski MCrowe SMPalmer CS. Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy.
PLoS ONE.
12.
2017
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Barrett TJMurphy AJGoldberg IJFisher EA. Diabetes-mediated myelopoiesis and the relationship to cardiovascular risk.
Annals of the New York Academy of Sciences.
1402:31-42.
2017
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Rahman MSMurphy AJWoollard KJ. Effects of dyslipidaemia on monocyte production and function in cardiovascular disease.
Nature Reviews Cardiology.
14:387-400.
2017
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Qin CXFinlayson SBAl-Sharea ATate MDe Blasio MJDeo MRosli SPrakoso DThomas CJKiriazis HGould EYang YHMorand EFPerretti MMurphy AJDu X-JGao X-MRitchie RH. Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.
Scientific Reports.
7:1-14.
2017
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Gao X-MTsai AAl-Sharea ASu YMoore SHan L-PKiriazis HDart AMMurphy AJDu X-J. Inhibition of the renin-angiotensin system post myocardial infarction prevents inflammation-associated acute cardiac rupture.
Cardiovascular Drugs and Therapy.
31:145-156.
2017
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Fleetwood AJLee MKSSingleton WAchuthan ALee M-CO'Brien-Simpson NMCook ADMurphy AJDashper SGReynolds ECHamilton JA. Metabolic remodeling, inflammasome activation, and pyroptosis in macrophagesstimulated by Porphyromonas gingivalis and its outer membrane vesicles.
Frontiers in cellular and infection microbiology.
7.
2017
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Kraakman MJLee MKSAl-Sharea ADragoljevic DBarrett TJMontenont EBasu DHeywood SKammoun HLFlynn MWhillas AHanssen NMJFebbraio MAWestein EFisher EAChin-Dusting JCooper MEBerger JSGoldberg IJNagareddy PRMurphy AJ. Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.
Journal of Clinical Investigation.
127:2133-2147.
2017
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Al-Sharea ALee MKSWhillas AFlynn MCChin-Dusting JMurphy AJ. Nicotinic acetylcholine receptor alpha 7 stimulation dampens splenic myelopoiesis and inhibits atherogenesis in Apoe ¯/¯ mice.
Atherosclerosis.
265:47-53.
2017
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Ganda AYvan-Charvet LZhang YLai EJRegunathan-Shenk RHussain FNAvasare RChakraborty BFebus AJVernocchi LLantigua RWang YShi XHsieh JMurphy AJWang NBijl NGordon KMde Miguel MHSinger JRHogan JCremers SMagnusson MMelander OGerszten RETall AR. Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD.
Journal of Molecular and Cellular Cardiology.
112:114-122.
2017
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Kowalski GMKraakman MJMason SAMurphy AJBruce CR. Resolution of glucose intolerance in long-term high-fat, high-sucrose-fed mice.
Journal of Endocrinology.
233:269-279.
2017
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Molloy CPYao YKammoun HBonnard THoefer TAlt KTovar-Lopez FRosengarten GRamsland PAvan der Meer ADvan den Berg AMurphy AJHagemeyer CEPeter KWestein E. Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation.
Journal of Thrombosis and Haemostasis.
15:972-982.
2017
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Shehata HMMurphy AJLee MKSGardiner CMCrowe SMSanjabi SFinlay DKPalmer CS. Sugar or fat?—metabolic requirements for immunity to viral infections.
Frontiers in Immunology.
8.
2017
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Fang LEllims AHBeale ALTaylor AJMurphy ADart AM. Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy.
American Journal of Translational Research.
9:5063-5073.
2017
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Lake NJTaylor RLTrahair HHarikrishnan KNCurran JEAlmeida MKulkarni HMukhamedova NHoang ALow HMurphy AJJohnson MPDyer TDMahaney MCGöring HHHMoses EKSviridov DBlangero JJowett JBMBozaoglu K. TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis.
European Heart Journal.
38:3579-3587.
2017
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Murphy AJTall AR. Disordered haematopoiesis and athero-thrombosis.
European Heart Journal.
37:1113-1121.
2016
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Lee MKSMoore X-LFu YAl-Sharea ADragoljevic DFernandez-Rojo MAParton RSviridov DMurphy AJChin-Dusting JPF. High-density lipoprotein inhibits human M1 macrophage polarization through redistribution of caveolin-1.
British Journal of Pharmacology.
173:741-751.
2016
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Murphy AJKraakman MJKammoun HLDragoljevic DLee MKSLawlor KEWentworth JMVasanthakumar AGerlic MWhitehead LWDiRago LCengia LLane RMMetcalf DVince JEHarrison LCKallies AKile BTCroker BAFebbraio MAMasters SL. IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Cell Metabolism.
23:155-164.
2016
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Al-Sharea ALee MKSMoore XLFang LSviridov DChin-Dusting JAndrews KLMurphy AJ. Native LDL promotes differentiation of human monocytes to macrophages with an inflammatory phenotype.
Thrombosis and Haemostasis.
115:762-772.
2016
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Lee MKSYvan-Charvet LMasters SLMurphy AJ. The modern interleukin-1 superfamily: Divergent roles in obesity.
Seminars in Immunology.
28:441-449.
2016
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Kraakman MJKammoun HLAllen TLDeswaerte VHenstridge DCEstevez EMatthews VBNeill BWhite DAMurphy AJPeijs LYang CRisis SBruce CRDu X-JBobik ALee-Young RSKingwell BAVasanthakumar AShi WKallies ALancaster GIRose-John SFebbraio MA. Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
Cell Metabolism.
21:403-416.
2015
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Westerterp MBochem AEYvan-Charvet LMurphy AJWang NTall AR. ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation.
Circulation Research.
114:157-170.
2014
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Kappus MSMurphy AJAbramowicz SNtonga VWelch CLTall ARWesterterp M. Activation of Liver X Receptor Decreases Atherosclerosis in Ldlr-/- Mice in the Absence of ATP-Binding Cassette Transporters A1 and G1 in Myeloid Cells.
Arteriosclerosis, Thrombosis and Vascular Biology.
34:279-284.
2014
Full text if available -
Nagareddy PRKraakman MMasters SLStirzaker RAGorman DJGrant RWDragoljevic DHong ESAbdel-Latif ASmyth SSChoi SHKorner JBornfeldt KEFisher EADixit VDTall ARGoldberg IJMurphy AJ. Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity.
Cell Metabolism.
19:821-835.
2014
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Murphy AJDragoljevic DTall AR. Cholesterol Efflux Pathways Regulate Myelopoiesis: A Potential Link to Altered Macrophage Function in Atherosclerosis.
Frontiers in Immunology.
5.
2014
Full text if available -
Murphy AJSarrazy VWang NBijl NAbramowicz SWesterterp MWelch CBSchuetz JDYvan-Charvet L. Deficiency of ATP-Binding Cassette Transporter B6 in Megakaryocyte Progenitors Accelerates Atherosclerosis in Mice.
Arteriosclerosis, Thrombosis and Vascular Biology.
34:751-758.
2014
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Ai DJiang HWesterterp MMurphy AJWang MGanda AAbramowicz SWelch CAlmazan FZhu YMiller YITall AR. Disruption of Mammalian Target of Rapamycin Complex 1 in Macrophages Decreases Chemokine Gene Expression and Atherosclerosis.
Circulation Research.
114:1576-1584.
2014
Full text if available -
Wang MSubramanian MAbramowicz SMurphy AJGonen AWitztum JWelch CTabas IWesterterp MTall AR. Interleukin-3/Granulocyte Macrophage Colony-Stimulating Factor Receptor Promotes Stem Cell Expansion, Monocytosis, and Atheroma Macrophage Burden in Mice With Hematopoietic ApoE Deficiency.
Arteriosclerosis, Thrombosis and Vascular Biology.
34:976-984.
2014
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Kraakman MJMurphy AJJandeleit-Dahm KKammoun HLNL. Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?.
Frontiers in Immunology.
5.
2014
Full text if available -
Murphy AJTall AR. Proliferating Macrophages Populate Established Atherosclerotic Lesions.
Circulation Research.
114:236-238.
2014
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Koulis CKanellakis PPickering RJTsorotes DMurphy AJGray SPThomas MCJandeleit-Dahm KAMCooper MEAllen TJ. Role of bone-marrow- and non-bone-marrow-derived receptor for advanced glycation end-products (RAGE) in a mouse model of diabetes-associated atherosclerosis.
Clinical Science.
127:485-497.
2014
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Distel EBarrett TJChung KGirgis NMParathath SEssau CCMurphy AJMoore KJFisher EA. miR33 Inhibition Overcomes Deleterious Effects of Diabetes Mellitus on Atherosclerosis Plaque Regression in Mice.
Circulation Research.
115:759-769.
2014
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Murphy AHoang AAprico ASviridov DChin-Dusting J. Anti-Inflammatory Functions of Apolipoprotein A-I and High-Density Lipoprotein Are Preserved in Trimeric Apolipoprotein A-I.
Journal of Pharmacology and Experimental Therapeutics.
344:41-49.
2013
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Murphy AJBijl NYvan-Charvet LWelch CBBhagwat NReheman AWang YShaw JALevine RLNi HTall ARWang N. Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.
Nature Medicine.
19:586-594.
2013
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Westerterp MMurphy AJWang MPagler TAVengrenyuk YKappus MSGorman DJNagareddy PRZhu XAbramowicz SParks JSWelch CFisher EAWang NYvan-Charvet LTall AR. Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice.
Circulation Research.
112:1456-1465.
2013
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Tsuchiya KWesterterp MMurphy AJSubramanian VFerrante AWTall ARAccili D. Expanded Granulocyte/Monocyte Compartment in Myeloid-Specific Triple FoxO Knockout Increases Oxidative Stress and Accelerates Atherosclerosis in Mice.
Circulation Research.
112:992-1003.
2013
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Tolani SPagler TAMurphy AJBochem AEAbramowicz SWelch CNagareddy PRHolleran SHovingh GKKuivenhoven JATall AR. Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: Studies in mice and FH children.
Atherosclerosis.
229:79-85.
2013
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Nagareddy PRMurphy AJStirzaker RAHu YYu SMiller RGRamkhelawon BDistel EWesterterp MHuang L-SSchmidt AMOrchard TJFisher EATall ARGoldberg IJ. Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis.
Cell Metabolism.
17:695-708.
2013
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Murphy AJFunt SGorman DTall ARWang N. Pegylation of High-Density Lipoprotein Decreases Plasma Clearance and Enhances Antiatherogenic Activity.
Circulation Research.
113:e1-e9.
2013
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Tall ARYvan-Charvet LWesterterp MMurphy AJ. Cholesterol Efflux.
Arteriosclerosis, Thrombosis and Vascular Biology.
32:2547-2552.
2012
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Eisenhardt SUStarke JThiele JRMurphy ABjörn Stark GBassler NSviridov DWinkler KPeter K. Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL–monocyte interactions.
Atherosclerosis.
224:384-393.
2012
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Westerterp MGourion-Arsiquaud SMurphy AJShih ACremers SLevine RLTall ARYvan-Charvet L. Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways.
Cell Stem Cell.
11:195-206.
2012
Full text if available -
Ai DBaez JMJiang HConlon DMHernandez-Ono AFrank-Kamenetsky MMilstein SFitzgerald KMurphy AJWoo CWStrong AGinsberg HNTabas IRader DJTall AR. Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.
Journal of Clinical Investigation.
122:1677-1687.
2012
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Ai DChen CHan SGanda AMurphy AJHaeusler RThorp EAccili DHorton JDTall AR. Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice.
Journal of Clinical Investigation.
122:1262-1270.
2012
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Murphy AJWesterterp MYvan-Charvet LTall AR. Anti-atherogenic mechanisms of high density lipoprotein: Effects on myeloid cells.
BBA: Molecular and Cell Biology of Lipids.
1821:513-521.
2012
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Murphy AKang KSchmahl JLee J-MGarcia KPatil KChen AKeene MMurphy ASleeman MW. Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption.
The FASEB Journal.
26:259-271.
2012
Full text if available -
Kuo C-LMurphy AJSayers SLi RYvan-Charvet LDavis JZKrishnamurthy JLiu YPuig OSharpless NETall ARWelch CL. Cdkn2a
Is an Atherosclerosis Modifier Locus That Regulates Monocyte/Macrophage Proliferation.
Arteriosclerosis, Thrombosis and Vascular Biology.
31:2483-2492.
2011
Full text if available -
Murphy AJAkhtari MTolani SPagler TBijl NKuo C-LWang MSanson MAbramowicz SWelch CBochem AEKuivenhoven JAYvan-Charvet LTall AR. ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.
Journal of Clinical Investigation.
121:4138-4149.
2011
Full text if available -
Murphy AJWoollard KJSuhartoyo AStirzaker RAShaw JSviridov DChin-Dusting JPF. Neutrophil Activation Is Attenuated by High-Density Lipoprotein and Apolipoprotein A-I in In Vitro and In Vivo Models of Inflammation.
Arteriosclerosis, Thrombosis and Vascular Biology.
31:1333-1341.
2011
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Pagler TAWang MMondal MMurphy AJWesterterp MMoore KJMaxfield FRTall AR. Deletion of ABCA1 and ABCG1 Impairs Macrophage Migration Because of Increased Rac1 Signaling.
Circulation Research.
108:194-200.
2011
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Murphy AJ. Murphy AT. Remaley ASviridov D. HDL Therapy: Two Kinds of Right?.
Current Pharmaceutical Design.
16:4134-4147.
2010
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D'Souza WStonik JAMurphy ADemosky SJSethi AAMoore XLChin-Dusting JRemaley ATSviridov D. Structure/Function Relationships of Apolipoprotein A-I Mimetic Peptides.
Circulation Research.
107:217-227.
2010
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Murphy AJWoollard KJ. High-density lipoprotein: A potent inhibitor of inflammation.
Clinical and Experimental Pharmacology and Physiology.
37:710-718.
2010
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Murphy AJChin-Dusting JSviridov D. Reconstituted HDL: a therapy for atherosclerosis and beyond.
Clinical Lipidology.
4:731-739.
2009
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Huynh NNAndrews KLHead GAKhong SMLMayorov DNMurphy AJLambert GKiriazis HXu QDu X-JChin-Dusting JPF. Arginase II Knockout Mouse Displays a Hypertensive Phenotype Despite a Decreased Vasoconstrictory Profile.
Hypertension.
54:294-301.
2009
Full text if available -
Eisenhardt SUHabersberger JMurphy AChen Y-CWoollard KJBassler NQian Hvon zur Muhlen CHagemeyer CEAhrens IChin-Dusting JBobik APeter K. Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques.
Circulation Research.
105:128-137.
2009
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Patel SDrew BGNakhla SDuffy SJMurphy AJBarter PJRye K-AChin-Dusting JHoang ASviridov DCelermajer DSKingwell BA. Reconstituted High-Density Lipoprotein Increases Plasma High-Density Lipoprotein Anti-Inflammatory Properties and Cholesterol Efflux Capacity in Patients With Type 2 Diabetes.
Journal of the American College of Cardiology.
53:962-971.
2009
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Murphy AChin-Dusting JPSviridov DWoollard K. The Anti Inflammatory Effects of High Density Lipoproteins.
Current Medicinal Chemistry.
16:667-675.
2009
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Shaw JABobik AMurphy AKanellakis PBlombery PMukhamedova NWoollard KLyon SSviridov DDart AM. Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque.
Circulation Research.
103:1084-1091.
2008
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Murphy AJWoollard KJHoang AMukhamedova NStirzaker RAMcCormick SPARemaley ATSviridov DChin-Dusting J. High-Density Lipoprotein Reduces the Human Monocyte Inflammatory Response.
Arteriosclerosis, Thrombosis and Vascular Biology.
28:2071-2077.
2008
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Rajinda Kekulawala JMurphy AD’Souza WWai CChin-Dusting JKingwell BSviridov DMukhamedova N. Impact of freezing on high-density lipoprotein functionality.
Analytical Biochemistry.
379:213-215.
2008
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Tikellis CJandeleit-Dahm KASheehy KMurphy AChin-Dusting JKling DSebokova ECooper MEMizrahi JWoollard KJ. Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.
Atherosclerosis.
199:55-64.
2008
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Hoang AMurphy AJCoughlan MTThomas MCForbes JMO’Brien RCooper MEChin-Dusting JPFSviridov D. Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.
Diabetologia.
50:1770-1779.
2007
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Murphy AWhite ANair RKingwell BDuffy SChin-Dusting JWoollard K. C-reactive protein and FcγRIIa functional polymorphisms are not associated with clinical presentation of stable and unstable angina.
Thrombosis and Haemostasis.
97:681-682.
2007
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Murphy AMertz JEMurphy ABarkan A. Mutants deleted in the agnogene of simian virus 40 define a new complementation group.
Journal of Virology.
45:36-46.
1983
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Barrett TJDistel EMurphy AJHu JGarshick MSOgando YLiu JVaisar THeinecke JWBerger JSGoldberg IJFisher EA. Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation.
Circulation.
140:1170-1184.
2019
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comment
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Pernes GLancaster GIMurphy AJ. Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment.
Gut.
1204-1206.
2018
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Lee MKSMurphy AJ. The iPSC Awakens ANGPTL3 in Tangier Disease.
EBioMedicine.
15-16.
2017
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Allen TJMurphy AJJandeleit-Dahm KA. RAGE Against the ABCs.
Diabetes.
3981-3983.
2015
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Murphy AJYvan-Charvet L. Adipose Modulation of ABCG1 Uncovers an Intimate Link Between Sphingomyelin and Triglyceride Storage: Figure 1.
Diabetes.
689-692.
2015
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Pernes GLancaster GIMurphy AJ. Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment.
Gut.
1204-1206.
2018
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editorial article
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Woollard KJMurphy AJ. The Endless Summer.
Circulation Research.
121:596-598.
2017
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Woollard KJMurphy AJ. The Endless Summer.
Circulation Research.
121:596-598.
2017
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erratum
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Qin CXFinlayson SBAl-Sharea ATate MDe Blasio MJDeo MRosli SPrakoso DThomas CJKiriazis HGould EYang YHMorand EFPerretti MMurphy AJDu X-JGao X-MRitchie RH. Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.
Scientific Reports.
7185.
2018
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Kraakman MJKammoun HLAllen TLDeswaerte VHenstridge DCEstevez EMatthews VBNeill BWhite DAMurphy AJPeijs LYang CRisis SBruce CRDu X-JBobik ALee-Young RSKingwell BAVasanthakumar AShi WKallies ALancaster GIRose-John SFebbraio MA. Blocking IL-6 trans-Signaling Prevents High-Fat Diet-Induced Adipose Tissue Macrophage Recruitment but Does Not Improve Insulin Resistance.
Cell Metabolism.
563-563.
2016
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Qin CXFinlayson SBAl-Sharea ATate MDe Blasio MJDeo MRosli SPrakoso DThomas CJKiriazis HGould EYang YHMorand EFPerretti MMurphy AJDu X-JGao X-MRitchie RH. Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.
Scientific Reports.
7185.
2018