selected publications
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academic article
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Kowalczyk WSanchez JKraaz PHutt OEHaylock DNDuggan PJ. The binding of boronated peptides to low affinity mammalian saccharides.
Peptide Science.
110:1-12.
2018
Full text if available -
Gilbert JReynolds NPRussell SMHaylock DMcArthur SCharnley MJones OG. Chitosan-coated amyloid fibrils increase adipogenesis of mesenchymal stem cells.
Materials Science and Engineering C: Biomimetic and Supramolecular Systems.
79:363-371.
2017
Full text if available -
Muerza-Cascante MLShokoohmand AKhosrotehrani KHaylock DDalton PDHutmacher DWLoessner D. Endosteal-like extracellular matrix expression on melt electrospun written scaffolds.
Acta Biomaterialia.
52:145-158.
2017
Full text if available -
Lee E-JMari CGel MGardiner JGasser GHaylock D. Immobilisation of Multiple Ligands Using Peptide Nucleic Acids: A Strategy to Prepare the Microenvironment for Cell Culture.
ChemistrySelect.
2:4028-4032.
2017
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Heazlewood SYNilsson SKCartledge KBe CLVinson AGel MHaylock DN. Progress in bio-manufacture of platelets for transfusion.
Platelets (London).
28:649-656.
2017
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Wang XHaylock DHu CSKowalczyk WJiang TQiu JMosoyan GHe WMarshall NMascarenhas JTarasova ABrody JWinkler DHoffman R. A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells.
Blood.
127:3398-3409.
2016
Full text if available -
Ng ESAzzola LBruveris FFCalvanese VPhipson BVlahos KHirst CJokubaitis VJYu QCMaksimovic JLiebscher SJanuar VZhang ZWilliams BConscience ADurnall JJackson SCosta MElliott DHaylock DNNilsson SKSaffery RSchenke-Layland KOshlack AMikkola HKAStanley EGElefanty AG. Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.
Nature Biotechnology.
34:1168-1183.
2016
Full text if available -
Gu DLadewig KKlimak MHaylock DMcLean KMO'Connor AJQiao GG. Amphiphilic core cross-linked star polymers as water-soluble, biocompatible and biodegradable unimolecular carriers for hydrophobic drugs.
Polymer Chemistry.
6:6475-6487.
2015
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Liang KRicco RDoherty CMStyles MJBell SKirby NMudie SHaylock DHill AJDoonan CJFalcaro P. Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Nature Communications.
6.
2015
Full text if available -
Storan MJHeazlewood SYHeazlewood CKHaylock DNAlexander WSNeaves RJOteiza ANilsson SK. Brief report: Factors released by megakaryocytes thrombin cleave osteopontin to negatively regulate hematopoietic stem cells.
Stem Cells.
33:2351-2357.
2015
Full text if available -
Henderson TMALadewig KHaylock DNMcLean KMO’Connor AJ. Formation and characterisation of a modifiable soft macro-porous hyaluronic acid cryogel platform.
Journal of Biomaterials Science: Polymer Edition.
26:881-897.
2015
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Winkler DLee EJBe CLVinson ARRiches AGFehr FGardiner JGengenbach TRWinkler DHaylock D. Immobilisation of a thrombopoietin peptidic mimic by self-assembled monolayers for culture of CD34+ cells.
Biomaterials.
37:82-93.
2015
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Muerza-Cascante MLHaylock DHutmacher DWDalton PD. Melt Electrospinning and Its Technologization in Tissue Engineering.
Tissue Engineering Part B: Reviews.
21:187-202.
2015
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Berry JDGodara PLiovic PHaylock DN. Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures.
Stem Cell Research and Therapy.
6.
2015
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Lee E-JGodara PHaylock D. Biomanufacture of human platelets for transfusion: Rationale and approaches.
Experimental Hematology.
42:332-346.
2014
Full text if available -
Cao BHutt OEZhang ZLi SHeazlewood SYWilliams BSmith JAHaylock DNSavage GPNilsson SK. Design, synthesis and binding properties of a fluorescent α₉β₁/α₄β₁ integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells.
Organic and Biomolecular Chemistry.
12:965-978.
2014
Full text if available -
Soh C-LGiudice AJenny RAElliott DAHatzistavrou TMicallef SJKianizad KSeach NZúñiga-Pflücker JCChidgey APTrounson ANilsson SKHaylock DNBoyd RLElefanty AGStanley EG. FOXN1GFP/w reporter hESCs enable identification of Integrin-β4, HLA-DR, and EpCAM as markers of human PSC-Derived FOXN1+ thymic epithelial progenitors.
Stem Cell Reports.
2:925-937.
2014
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Gel MKandasamy SCartledge KHaylock D. Fabrication of free standing microporous COC membranes optimized for in vitro barrier tissue models.
Sensors and Actuators A: Physical.
215:51-55.
2014
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Henderson TMALadewig KHaylock DNMcLean KMO'Connor AJ. Cryogels for biomedical applications.
Journal of Materials Chemistry B.
1:2682-2695.
2013
Full text if available -
Borghi FFRider AEKumar SHan ZJHaylock DOstrikov K. Emerging Stem Cell Controls: Nanomaterials and Plasma Effects.
Journal of Nanomaterials.
2013:1-15.
2013
Full text if available -
Heazlewood SYNeaves RJWilliams BHaylock DNAdams TENilsson SK. Megakaryocytes co-localise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation.
Stem Cell Research.
11:782-792.
2013
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Tarasova AHaylock DMeagher LBe CWhite JNilsson SAndrade JCartledge KWinkler D. Potent Agonists of a Hematopoietic Stem Cell Cytokine Receptor, c-Mpl.
ChemMedChem: chemistry enabling drug discovery.
8:763-771.
2013
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Grassinger JWilliams BOlsen GHHaylock DNNilsson SK. Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region.
Cytokine.
58:218-225.
2012
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Ellis SLGrassinger JJones ABorg JCamenisch THaylock DBertoncello INilsson SK. The relationship between bone, hemopoietic stem cells, and vasculature.
Blood.
118:1516-1524.
2011
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Tarasova AHaylock DWinkler D. Principal signalling complexes in haematopoiesis: structural aspects and mimetic discovery.
Cytokine and Growth Factor Reviews.
22:231-253.
2011
Full text if available -
Prowse ABJDoran MRCooper-White JJChong FMunro TPFitzpatrick JChung T-LHaylock DNGray PPWolvetang EJ. Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media.
Biomaterials.
31:8281-8288.
2010
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Grassinger JHaylock DNWilliams BOlsen GHNilsson SK. Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential.
Blood.
116:3185-3196.
2010
Full text if available -
Winkler DAndrade JCablewski TCondie GHaylock DMeagher LRiches ATarasova AWerkmeister JWhite JWinkler D. Zinc Is Not Required for Activity of TPO Agonists Acting at the c-Mpl Receptor Transmembrane Domain.
ACS Chemical Biology.
5:741-745.
2010
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Nigro JWhite JFRamshaw JAMHaylock DNNilsson SKWerkmeister JA. The effect of bovine endosteum-derived particles on the proliferation of human mesenchymal stem cells.
Biomaterials.
31:5689-5699.
2010
Full text if available -
Powell JAThomas DBarry EFKok CHMcClure BJTsykin ATo LBBrown ALewis IDHerbert KGoodall GJSpeed TPAsou NJacob BOsato MHaylock DNNilsson SKD'Andrea RJLopez AFGuthridge MA. Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.
Blood.
114:4859-4870.
2009
Full text if available -
Grassinger JHaylock DNStoran MJHaines GOWilliams BWhitty GAVinson ARBe CLLi SSørensen ESTam PPLDenhardt DTSheppard DChoong PFNilsson SK. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with α9β1 and α4β1 integrins.
Blood.
114:49-59.
2009
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Herbert KELévesque J-PHaylock DNPrince M. The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell Mobilization.
Biology of Blood and Marrow Transplantation.
14:603-621.
2008
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Jokubaitis VJSinka LDriessen RWhitty GHaylock DNBertoncello ISmith IPéault BTavian MSimmons PJ. Angiotensin-converting enzyme (CD143) marks hematopoietic stem cells in human embryonic, fetal, and adult hematopoietic tissues.
Blood.
111:4055-4063.
2008
Full text if available -
Grassinger JMueller GHart CNilsson SKHaylock DNAndreesen RHennemann B. Detection and quantification of functionally defined hematopoietic progenitor cells and tissue specific mRNA within the peripheral blood of myeloma patients after administration of granulocyte colony-stimulating factor and erythropoietin.
European Journal of Haematology.
0:071119202650003-???.
2008
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Haylock DNilsson S. Expansion of Umbilical Cord Blood for Clinical Transplantation.
Current Stem Cell Research and Therapy.
2:324-335.
2007
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Haylock DNWilliams BJohnston HMLiu MCPRutherford KEWhitty GASimmons PJBertoncello INilsson SK. Hemopoietic Stem Cells with Higher Hemopoietic Potential Reside at the Bone Marrow Endosteum.
Stem Cells.
25:1062-1069.
2007
Full text if available -
Haylock DNWilliams BJohnston HMLiu MCPRutherford KEWhitty GASimmons PJBertoncello INilsson SK. Hemopoietic stem cells with higher hemopoietic potential reside at the bone marrow endosteum.
Stem Cells.
25:1062-1069.
2007
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Nilsson SKPrince HMWall DHaylock DN. Recent Australian experience with hemopoietic stem and progenitor cell expansion.
Cytotherapy.
9:231-235.
2007
Full text if available -
Laslett ALGrimmond SGardiner BStamp LLin AHawes SMWormald SNikolic-Paterson DHaylock DPera MF. Transcriptional analysis of early lineage commitment in human embryonic stem cells.
BMC Developmental Biology.
7:12-12.
2007
Full text if available -
Missen MAHaylock DWhitty GMedcalf RLCoughlin PB. Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation.
British Journal of Haematology.
135:715-724.
2006
Full text if available -
Haylock DNNilsson SK. Osteopontin: a bridge between bone and blood.
British Journal of Haematology.
134:467-474.
2006
Full text if available -
Haylock DNNilsson SK. Osteopontin: a bridge between bone and blood.
British Journal of Haematology.
134:467-474.
2006
Full text if available -
Haylock DNNilsson SK. The role of hyaluronic acid in hemopoietic stem cell biology.
Regenerative Medicine.
1:437-445.
2006
Full text if available -
Boyle AJWhitbourn RSchlicht SKrum HKocher ANandurkar HBergmann SDaniell MO'Day JSkerrett DHaylock DGilbert REItescu S. Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: A 12-month follow-up.
International Journal of Cardiology.
109:21-27.
2006
Full text if available -
Haylock DNNilsson SK. Stem Cell Regulation by the Haemopoietic Stem Cell Niche.
Cell Cycle.
4:1353-1355.
2005
Full text if available -
Nilsson SKJohnston HMWhitty GAWilliams BWebb RJDenhardt DTBertoncello IBendall LJSimmons PJHaylock DN. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells.
Blood.
106:1232-1239.
2005
Full text if available -
Miles Prince HSimmons PJWhitty GWall DPBarber LToner GCSeymour JFRichardson GMrongovius RHaylock DN. Improved haematopoietic recovery following transplantation with ex vivo-expanded mobilized blood cells*.
British Journal of Haematology.
126:536-545.
2004
Full text if available -
Nilsson SKHaylock DNJohnston HMOcchiodoro TBrown TJSimmons PJ. Hyaluronan is synthesized by primitive hemopoietic cells, participates in their lodgment at the endosteum following transplantation, and is involved in the regulation of their proliferation and differentiation in vitro.
Blood.
101:856-862.
2003
Full text if available -
Prince HMWall DRischin DToner GCSeymour JFBlakey DHaylock DSimmons PWolf MJanuszewicz EHWesterman DRichardson GScarlett JBriggs P. CliniMACS CD34-selected cells to support multiple cycles of high-dose therapy.
Cytotherapy.
4:147-155.
2002
Full text if available -
Prince HMBashford JWall DRischin DParker NToner GCSeymour JFBlakey DHaylock DSimmons PFrancis PWolf MJanuszewicz EHRichardson GScarlett JBriggs P. Isolex 300i CD34-selected cells to support multiple cycles of high-dose therapy.
Cytotherapy.
4:137-145.
2002
Full text if available -
Lévesque J-PTakamatsu YNilsson SKHaylock DNSimmons PJ. Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor.
Blood.
98:1289-1297.
2001
Full text if available -
Haylock DNRamshaw H. Monoclonal antibody BB9 raised against bone marrow stromal cells identifies a cell-surface glycoprotein expressed by primitive human hemopoietic progenitors.
Experimental Hematology.
29:981-992.
2001
Full text if available -
Prince HMWall DChapple PQuinn MBrettell MHaylock DSeymour JFWolf MJanuscewicz HRichardson GJoyce TMaisano RRischin D. CliniMACS CD34-selected cells to support high-dose therapy.
Transfusion and Apheresis Science.
24:183-183.
2001
Full text if available -
SIMMONS PAULJLEVESQUE JEAN-PIERREHAYLOCK DAVIDN. Mucin-like Molecules as Modulators of the Survival and Proliferation of Primitive Hematopoietic Cells.
Annals of the New York Academy of Sciences.
938:196-207.
2001
Full text if available -
Lévesque JPTakamatsu YNilsson SKHaylock DNSimmons PJ. Role of integrins and selectins in the development and regulation of the hematopoietic system.
Hematologie.
7:99-109.
2001
-
Haylock DNSimmons PJ. Isolation of primitive haemopoietic progenitors by prestimulation with hgf and incubation with 5-fu.
Blood.
96.
2000
-
Levesque JPTakamatsu YNilsson SKHaylock DNSimmons PJ. Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow.
Blood.
96.
2000
-
Chapple PPrince HMWall DFilshie RHaylock DQuinn MBretell MVenter D. Comparison of three methods of CD34+ cell enumeration in peripheral blood: Dual-platform ISHAGE protocol versus single-platform, versus microvolume fluorimetry.
Cytotherapy.
2:371-376.
2000
Full text if available -
Lévesque J-PZannettino ACWPudney MNiutta SHaylock DNSnapp KRKansas GSBerndt MCSimmons PJ. PSGL-1-Mediated Adhesion of Human Hematopoietic Progenitors to P-Selectin Results in Suppression of Hematopoiesis.
Immunity.
11:369-378.
1999
Full text if available -
To LBHaylock DNSimmons PJ. Clinical application of ex vivo expanded cells.
Cancer Research, Therapy and Control.
7:97-101.
1998
-
Moore SHaylock DNLévesque J-PMcDiarmid LASamels LMTo LBSimmons PJHughes TP. Stem Cell Factor as a Single Agent Induces Selective Proliferation of the Philadelphia Chromosome Positive Fraction of Chronic Myeloid Leukemia CD34+ Cells.
Blood.
92:2461-2470.
1998
Full text if available -
Tapp HBik To LHaylock D. Advances in peripheral blood stem cell transplantation.
Clinical Immunology Newsletter.
17:159-162.
1997
Full text if available -
MARINO SHIGEYOSHIHAYLOCK DAVIDNDOWSE TRACEYTRIMBOLI SANDRANIUTTA SILVANATO LUENBJUTTNER CHRISTOPHERASIMMONS PAULJ. Ex Vivo Culture of Peripheral Blood CD34+ Cells: Effects of Hematopoietic Growth Factors on Production of Neutrophilic Precursors.
Stem Cells and Development.
6:475-489.
1997
Full text if available -
Haylock DNHorsfall MJDowse TLRamshaw HSNiutta SProtopsaltis SPeng LBurrell CRappold IBuhring HJSimmons PJ. Increased recruitment of hematopoietic progenitor cells underlies the ex vivo expansion potential of FLT3 ligand.
Blood.
90:2260-2272.
1997
-
Lewis IDHaylock DNMoore STo LBHughes TP. Peripheral blood is a source of BCR-ABL-negative pre-progenitors in early chronic phase chronic myeloid leukemia.
Leukemia.
11:581-587.
1997
Full text if available -
To LBHaylock DNSimmons PJJuttner CA. The Biology and Clinical Uses of Blood Stem Cells.
Blood.
89:2233-2258.
1997
Full text if available -
White DLHutchins CJTurczynowicz SSuttle JHaylock DNHughes TPJuttner CATo LB. Detection of minimal residual disease in an AML patient with trisomy 8 using interphase FISH.
Pathology.
29:289-293.
1997
Full text if available -
Ramshaw HSLi PHaylock DNHorsfall MJPeng HMercure LSimmons PJ. Increased recruitment of primitive hematopoietic progenitor cells by FLT3 ligand leads to enhanced rates of retroviral transduction.
Experimental Hematology.
24:1058.
1996
-
LEWIS IDRAWLING TDYSON PGHAYLOCK DNJUTTNER CATO LB. Standardization of the CFU-GM Assay Using Hematopoietic Growth Factors.
Stem Cells and Development.
5:625-630.
1996
Full text if available -
Levesque JHaylock DSimmons P. The dual orchestration of haemopoiesis by adhesive proteins and cytokines.
Cancer Forum.
20:272-274.
1996
-
Levesque JPHaylock DNSimmons PJ. Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hemopoietic progenitors.
Blood.
88:1168-1176.
1996
Full text if available -
Nordon REHaylock DNGaudry LSchindhelm K. Hollow-fibre affinity cell separation system for CD34+ cell enrichment.
Cytometry.
24:340-347.
1996
Full text if available -
White DLHutchins CJHaylock DNTurczynowicz SBishop ATo LBHughes TPJuttner CA. Direct analysis of FACS-sorted hemopoietic cell fractions using FISH.
BioTechniques: the journal of laboratory technology for bioresearch.
18:818-821.
1995
-
Simmons PJHaylock DN. Use of hematopoietic growth factors for in vitro expansion of precursor cell populations.
Current Opinion in Hematology.
2:189-195.
1995
Full text if available -
Haylock DNMakino SDowse TLTrimboli SNiutta STo LBJuttner CASimmons PJ. Ex Vivo Hematopoietic Progenitor Cell Expansion.
ImmunoMethods.
5:217-225.
1994
Full text if available -
Simmons PJLeavesley DILevesque JPSwart BWHaylock DNTo LBAshman LKJuttner CA. The mobilization of primitive hemopoietic progenitors into the peripheral blood.
Stem Cells.
12:187-201.
1994
-
Leavesley DIOliver JMSwart BWBerndt MCHaylock DNSimmons PJ. Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells.
Journal of Immunology.
153:4673-4683.
1994
-
Moretti PSimmons PThomas PHaylock DRathjen PVadas MD'Andrea R. Identification of homeobox genes expressed in human haemopoietic progenitor cells.
Gene.
144:213-219.
1994
Full text if available -
To LBHaylock DNDowse TSimmons PJTrimboli SAshman LKJuttner CA. A comparative study of the phenotype and proliferative capacity of peripheral blood (PB) CD34+cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34+cells.
Blood.
84:2930-2939.
1994
-
To LBStemmelin GRHaylock DNBayly JLThorp DRawling CMTrimboli SJuttner CA. Collection efficiency on the fenwal CS3000 when using filgrastim (recombinant methionyl human granulocyte colony-stimulating factor) as a peripheral blood stem cell mobilization agent.
Journal of Clinical Apheresis.
9:17-20.
1994
Full text if available -
Dyson PGHo JQKDowse TLHaylock DNJuttner CABik To L. The use of the APAAP technique as a rapid indicator of peripheral blood progenitor cell levels.
Pathology.
26:296-300.
1994
Full text if available -
Haylock DNTo LBDowse TLJuttner CASimmons PJ. Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage.
Blood.
80:1405-1412.
1992
-
Hardy SJHaylock DNLopez AFMurray AW. Examination of the role of the proteolytically-activated form of protein kinase C in the differentiation of human haemopoietic cells.
Differentiation.
50:189-202.
1992
Full text if available -
Gronthos STo LBHaylock DNJuttner CA. A differential sensitivity to recombinant human interferon-alpha 2a between normal and chronic myeloid leukaemic peripheral blood granulocyte-macrophage colony-forming units.
Leukemia Research: clinical and laboratory studies.
16:153-158.
1992
Full text if available -
To LBHaylock DNDyson PGRawling TPBayly JLRawling CMCanty ANWake BThorp DJuttner CA. A comparison between 4 GM/M2 and 7 GM/M2 cyclophosphamide for peripheral blood stem cell mobilization.
International Journal of Cell Cloning.
10:33-34.
1992
Full text if available -
Haylock DNCanty AThorp DDyson PGJuttner CABikto L. A discrepancy between the instantaneous and the overall collection efficiency of the fenwal CS3000 for peripheral blood stem cell apheresis.
Journal of Clinical Apheresis.
7:6-11.
1992
Full text if available -
Juttner CADavy MLJTo LBHaylock DNDyson PGRawling CMBayly JL. Autologous PBSC transplantation in stage 3 and 4 ovarian cancer.
International Journal of Cell Cloning.
10:145-145.
1992
Full text if available -
To LBRoberts MMHaylock DNDyson PGBranford ALThorp DHo JQKDart GWHorvath NDavy MLJOlweny CLMAbdi EJuttner CA. Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants.
Bone Marrow Transplantation.
9:277-284.
1992
-
Juttner CATo LBRoberts MMHaylock DDyson PGBranford ALThorp DHo JQKDart GWHorvath NDavy MLJOlweny CLMAbdi E. Comparison of haematological recovery, toxicity and supportive care of autologous PBSC, autologous BM and allogeneic BM transplants.
International Journal of Cell Cloning.
10:160-161.
1992
Full text if available -
FREWIN DBDYER SMHAYLOCK DNBATES IRDAVIS KGBEAL RW. A COMPARATIVE-STUDY OF THE EFFECT OF 3 METHODS OF LEUKOCYTE REMOVAL ON PLASMA HISTAMINE LEVELS IN STORED HUMAN BLOOD.
Seminars in Hematology.
28:18-21.
1991
-
Frewin DBDyer SMHaylock DNBates IRDavis KGBeal RW. A comparative study of the effect of three methods of leukocyte removal on plasma histamine levels in stored human blood.
Seminars in Hematology.
28:18-21.
1991
-
Frewin DBDyer SMHaylock DNBates IRDavis KGBeal RW. A comparative study of the effect of three methods of leukocyte removal on plasma histamine levels in stored human blood..
Seminars in Hematology.
28:18-21.
1991
-
Gianni AMSiena SBregni MTo LBShepperd KMHaylock DN. Letter to the editor.
Experimental Hematology.
19:147-148.
1991
-
To LBShepperd KMHaylock DNDyson PGCharles PThorp DLDale BMDart GWRoberts MMSage REJuttner CA. Single high doses of cyclophosphamide enable the collection of high numbers of hemopoietic stem cells from the peripheral blood.
Experimental Hematology.
18:442-447.
1990
-
Haylock DNDyson PGThorp DRoberts Juttner MMCA. An unusual pattern of hemopoietic reconstitution in patients with acute myeloid leukemia transplanted with autologous recovery phase peripheral blood.
Bone Marrow Transplantation.
6:109-114.
1990
-
Juttner CATo LBHaylock DNDyson PGBradstock KFDale BMEnno ASage RESzer JToogood IRG. Approaches to blood stem cell mobilisation. Initial Australian clinical results.
Bone Marrow Transplantation.
5:22-24.
1990
-
Haylock DThorp DTo LCanty AWhiting JJuttner CDart G. Assessing the stem cell collection efficiency of the Fenwal CS3000..
Progress in Clinical and Biological Research.
337:67-69.
1990
-
Juttner CATo LBHaylock DNDyson PG. Peripheral blood stem cell selection, collection and auto-transplantation..
Progress in Clinical and Biological Research.
333:447-460.
1990
-
To LBDavy MLHaylock DNDyson PGThorp DJuttner CA. Autotransplantation using peripheral blood stem cells mobilized by cyclophosphamide..
Bone Marrow Transplantation.
4:595-596.
1989
-
JUTTNER CATO LBHAYLOCK DNDYSON PGTHORP DDART GWHO JQKHORVATH NBARDY P. AUTOLOGOUS BLOOD STEM-CELL TRANSPLANTATION.
Transplantation Proceedings.
21:2929-2931.
1989
-
Juttner CATo LBHaylock DNDyson PGThorp DDart GWHo JQHorvath NBardy P. Autologous blood stem cell transplantation..
Transplantation Proceedings.
21:2929-2931.
1989
-
Juttner CATo LBHaylock DNDyson PGThorp DDart GWHo JQKHorvath NBardy P. Autologous blood stem cell transplantation.
Transplantation Proceedings.
21:2929-2931.
1989
-
To LBHaylock DNThorp DDyson PGBranford ALHo JQKDart GDRoberts MMHorvath NBardy PRussell JAMillar JLKimber RJJuttner CA. The optimization of collection of peripheral blood stem cells for autotransplantation in acute myeloid leukaemia.
Bone Marrow Transplantation.
4:41-47.
1989
-
Haylock DNTo LBJuttner CA. A simplified bone marrow cryopreservation method..
Blood.
72:1102-1103.
1988
-
JUTTNER CADYSON PGTO LBHO JQKHAYLOCK DNROBERTS MM. AUTOLOGOUS BLOOD STEM-CELL TRANSPLANTATION IN ACUTE MYELOID-LEUKEMIA.
Lancet.
1:419-420.
1988
-
Reiffers JMarit GDavid BBernard PHBroustet AJuttner CADyson PGTo LBHo JQKHaylock DNRoberts MM. AUTOLOGOUS BLOOD STEM CELL TRANSPLANTATION IN ACUTE MYELOID LEUKAEMIA.
Lancet.
331:419-420.
1988
Full text if available -
Juttner CATo LBHo JQKBardy PGDyson PGHaylock DNKimber RJ. Early lympho-hemopoietic recovery after autografting using peripheral blood stem cells in acute non-lymphoblastic leukemia.
Transplantation Proceedings.
20:40-42.
1988
-
To LBDyson PGBranford ALRussell JAHaylock DNHo JQKimber RJJuttner CA. Peripheral blood stem cells collected in very early remission produce rapid and sustained autologous haemopoietic reconstitution in acute non-lymphoblastic leukaemia.
Bone Marrow Transplantation.
2:103-108.
1987
-
To LBDyson PGBranford ALHaylock DNKimber RJJuttner CA. CFU-Mix are no better than CFU-GM in predicting hemopoietic reconstitutive capacity of peripheral blood stem cells collected in the very early remission phase of acute nonlymphoblastic leukemia.
Experimental Hematology.
15:351-354.
1987
-
Zola HPotter ANeoh SHJuttner CAHaylock DNRice AMFavaloro EJKabral ABradstock KF. Evaluation of a monoclonal IgM antibody for purging of bone marrow for autologous transplantation.
Bone Marrow Transplantation.
1:297-301.
1987
-
Frewin DBJonsson JRDavis KGBeilby AMHaylock DNBeal RWRussell WJ. Effect of Microfiltration on the Histamine Levels in Stored Human Blood.
Vox Sanguinis: international journal of transfusion medicine.
52:191-194.
1987
Full text if available -
Juttner CATo LBDyson PHaylock DNBranford AKimber RJ. THE PERIPHERAL BLOOD CFU-mix: CFU-GM RATIO DURING VERY EARLY REMISSION FROM ACUTE NON-LYMPHOBLASTIC LEUKAEMIA.
British Journal of Haematology.
62:598-599.
1986
Full text if available -
Bradstock KFFavaloro EJKabral AKerr APrendergast MBerndt MCHughes WGZola HKrishnan RHaylock DJuttner C. Standardization of monoclonal antibodies for use in autologous bone marrow transplantation for common acute lymphoblastic leukemia.
Pathology.
18:197-205.
1986
Full text if available -
Juttner CATo LBHaylock DNBranford AKimber RJ. Circulating autologous stem cells collected in very early remission from acute non-lymphoblastic leukaemia produce prompt but incomplete haemopoietic reconstitution after high dose melphalan or supralethal chemoradiotherapy.
British Journal of Haematology.
61:739-745.
1985
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To LBHaylock DNKimber RJJuttner CA. High levels of circulating haemopoietic stem cells in very early remission from acute non-lymphoblastic leukaemia and their collection and cryopreservation.
British Journal of Haematology.
58:399-410.
1984
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TO LBHAYLOCK DNJUTTNER CAKIMBER RJ. THE EFFECT OF MONOCYTES IN THE PERIPHERAL-BLOOD CFU-C ASSAY SYSTEM.
Blood.
62:112-117.
1983
-
To LBHaylock DNJuttner CAKimber RJ. The effect of monocytes in the peripheral blood.
Blood.
62:112-117.
1983
-
Kowalczyk WSanchez JKraaz PHutt OEHaylock DNDuggan PJ. The binding of boronated peptides to low affinity mammalian saccharides.
Peptide Science.
110:1-12.
2018
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chapter
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Haylock DNNilsson SK. Hematopoietic microenvironment and age.
71-83.
2007
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Haylock DNSimmons PJ. Approaches to Hematopoietic Stem Cell Separation and Expansion.
615-629.
2004
Full text if available
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Haylock DNNilsson SK. Hematopoietic microenvironment and age.
71-83.
2007
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conference paper
-
Berry JDGodara PLiovic PHaylock D. Evaluation of a groove bioreactor for stem cell expansion: Effects of inhibitory signalling.
Proceedings of the 19th Australasian Fluid Mechanics Conference, AFMC 2014.
2014
-
Gel MKandasamy SCartledge KHaylock D. Fabrication of micro pore arrays in free standing COC membranes and their application for in vitro barrier tissue models.
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS).
895-898.
2013
Full text if available -
Gel MKandasamy SCartledge KBe CLHaylock D. Micro pore arrays in free standing cyclic olefin copolymer membranes: fabrication and surface functionalization strategies for in-vitro barrier tissue models.
Proceedings of SPIE - The International Society for Optical Engineering.
2013
Full text if available -
Haylock DNGodara PLee ECartledge KNowell CMarchesan SNilsson SBe C. BIOREACTOR-BASED CULTURE OF CD34+CELLS FOR EX VIVO MEGAKARYOCYTE AND PLATELET PRODUCTION.
Experimental Hematology.
S79-S79.
2011
-
Shen YNeaves RJWilliams BHeazlewood CKReitsma AJHaylock DNMcCourt PANilsson SK. THE ROLE OF FRESHLY ISOLATED MEGAKARYOCYTES IN HAEMATOPOIETIC STEM CELL REGULATION.
Experimental Hematology.
S14-S15.
2011
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Grassinger JStoran MWilliams BOlsen GHaylock DNNilsson SK. Homing, proliferation and mobilization of hematopoietic stem cells is regulated through the interaction of alpha(9)beta(1) and Osteopontin.
Onkologie: international journal for cancer research and treatment.
217-217.
2010
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Loveland KLMithraprabhu SNeaves RJWilliams BOlsen GHMatzuk MMBrown CWHaylock DNNilsson SK. ACTIVIN SIGNALLING MODULATION IS CRITICAL FOR NORMAL HEMATOPOIESIS IN ADULT MOUSE.
Experimental Hematology.
S101-S101.
2010
-
Storan MJHaylock DNNeaves RJWhitty GADacumos-Hill AWilliams BNilsson SK. COMPONENTS OF THE PROTHROMBINASE COMPLEX ARE EXPRESSED BY MEGAKARYOCYTES AND THE ENDOSTEAL REGION OF THE BONE MARROW NICHE.
Experimental Hematology.
S88-S88.
2010
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Haylock DNAndrade JWhite JNilsson SKMeagher LCableswki TTarasova ABe CLRiches AWinkler D. DESIGN, SYNTHESIS AND FUNCTION OF NOVEL AGONIST AND ANTAGONIST THROMBOPOIETIN MIMICS.
Experimental Hematology.
S93-S93.
2010
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Grassinger JStoran MWilliams BOlsen GSheppard DHaylock DNNilsson SK. HEMATOPOIETIC STEM CELLS ARE REGULATED THROUGH THE INTERACTION OF ALPHA9 BETA1 AND OSTEOPONTIN.
Experimental Hematology.
S92-S93.
2010
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Powell JAThomas DBarry EFKok CHMa LYTo LBBrown ALewis IDGoodall GJSpeed TPWoodcock JOsato MEkert PGHaylock DNNilsson SKD'Andrea RJLopez AFGuthridge MA. TARGETING CELL SURVIVAL PATHWAYS IN ACUTE MYELOID LEUKEMIA.
Experimental Hematology.
S60-S60.
2010
-
Thomas DPowell JABarry EFWoodcock JEkert PGGreen BDLee EMLock RBNilsson SKHaylock DNLopez AFGuthridge MA. THE PROTEIN KINASE ACTIVITY OF PHOSPHOINOSITIDE 3-KINASE ALPHA PROMOTES AUTONOMOUS CELL SURVIVAL IN AML STEM/PROGENITOR CELLS.
Experimental Hematology.
S87-S87.
2010
-
Neaves JHaylock DNShen YNilsson SK. THE ROLE OF FRESHLY ISOLATED MATURE MEGAKARYOCYTES IN REGULATING HSC FUNCTION IN VITRO AND IN VIVO.
Experimental Hematology.
S27-S27.
2010
-
Nilsson SKGrassinger JHaines GWilliams BHaylock DN. LOCATION RATHER THAN PHENOTYPE IS CRITICAL FOR HSC FUNCTION.
Experimental Hematology.
S10-S10.
2009
-
Haylock DNAndrade JWhite JNilsson SKMeagher LCableswki TSchwab KTarasova ACondie GRiches AWinkler D. NOVEL THROMBOPOIETIN MIMICS FOR HAEMOPOIETIC STEM CELL EXPANSION.
Experimental Hematology.
S26-S26.
2009
-
Neaves RJHaylock DNNilsson SK. REGULATION OF MURINE HEMATOPOIETIC STEM CELLS BY MATURE MEGAKARYOCYTES IN THE ENDOSTEAL STEM CELL NICHE.
Experimental Hematology.
S33-S33.
2009
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Haylock DNStoran MGrassinger JWilliams BWhitty GAUede TNilsson SK. Regulation of haemopoietic stem cells by OPN is mediated by specific interactions with α4β1 and α9β1 integrins.
Cell Research.
S10-S10.
2008
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Ellis SLGrassinger JWilliams BAsquith SHaines GHaylock DBertoncello INilsson SK. The histo-morphometric relationship between bone, blood vessels and hemopoietic stem cells..
Microscopy and Microanalysis.
1466-1467.
2008
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Grassinger JHaines GWilliams BHaylock DNNilsson SK. Blocking CD48 significantly decreases trans-endothelial migration of murine hematopoietic stem cells (HSC): Implications for homing and engraftment.
Experimental Hematology.
S77-S77.
2008
-
Grassinger JHaines GWilliams BHaylock DNNilsson SK. Blocking CD48 significantly decreases trans-endothelial migration of murine hematopoietic stem cells (HSC): Implications for homing and engraftment.
Experimental Hematology.
S16-S17.
2008
-
Haylock DNGrassinger JWilliams BHaines GNilsson SK. Hyaluronic acid synthesised by HAS-3 plays a critical role in HSC homing and regulation.
Experimental Hematology.
S16-S16.
2008
-
Storan MHaylock DNGrassinger JWilliams BHaines GOWhitty GANilsson SK. The cleaved form of osteopontin interactions with square(4)square(1) and square(9)square(1) integrins play a key role in regulating haemopoietic stem cell functions.
Experimental Hematology.
S72-S72.
2008
-
Storan MHaylock DNGrassinger JWilliams BHaines GOWhitty GANilsson SK. The cleaved form of osteopontin interactions with square(4)square(1) and square(9)square(1) integrins play a key role in regulating haemopoietic stem cell functions.
Experimental Hematology.
S16-S16.
2008
-
Shaw SEHaylock DNJohnston HMLock RNilsson SK. 708 the role of hyaluronic acid in normal and perturbed hemopoietic stem cell biology..
Blood.
212A-213A.
2006
-
Haylock DNWhitty GAWilliams BStoran MJNilsson SK. Interaction and Regulation of HSC with Osteopontin Is Mediated through α4β1 and α9β1Integrins, Which Are Differentially Expressed in the HSC Pool..
Blood.
1330-1330.
2006
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Haylock DNJohnston HMWhittty GAWebb RJNilsson SK. The integrins of alpha(4)beta(1) and alpha(9)beta(1) mediate interaction with and regulation of hemopoietic stem cells by osteopontin.
Experimental Hematology.
43-43.
2006
-
Nilsson SKWhitty GABertoncello IWilliams BSimmons PJHaylock DN. An optimal method for isolating murine haemopoietic stem cells; More cells with significantly enhanced haemopoietic potential.
Cytometry Part B: Clinical Cytometry.
401-401.
2006
-
Haylock DNJohnston HMBrown TWebb RJWilliams BLiu MCPRutherford KENilsson SK. Haemopoietic stem cells regulate their interaction with their niche by hyaluronic acid synthesis and degradation.
Cytometry Part B: Clinical Cytometry.
407-407.
2006
-
Haylock DNWhitty GAJohnston HMWilliams BWebb RJBertoncello ISimmons PJNilsson SK. Osteopontin regulates haemopoietic stem cells via alpha(4) beta(1) and alpha(9) beta(1) integrins.
Cytometry Part B: Clinical Cytometry.
417-418.
2006
-
Haylock DNBoyle AWhitty GBarber LPrince HMBergman SSkerrett DItescu S. Mobilisation, apherests, selection and coronary artery infusion of CD34+cells for stable chronic ischaemic heart disease.
Experimental Hematology.
80-80.
2004
-
Prince MHaylock DNSimmons PJWall DMrongovius RWhitty GBarber LMints-Kotowska LTeoh L. Transplantation with ex vivo expanded mobilized blood CD34(+) cells results in reduction in depth and duration of neutropenia and thrombocytopenia, with major impact on febrile neutropenia, platelet transfusion and hospital admissions..
Blood.
237A-237A.
2003
-
Tavian MBrouard NNoel FHaylock DNSimmons PJPeault B. BB9, a surface molecule of adult bone marrow stromal cells, marks candidate multipotent pre-HSC within the para-aortic splanchnopleura in the human embryo..
Blood.
506A-507A.
2002
-
Purton LEDworkin SWalkley CRHaylock DNMcArthur GAChambon P. Deficiency of retinoic acid receptor gamma in mice results in multiple hematopoietic abnormalities..
Blood.
735A-735A.
2002
-
Winkler IGEto TPurton LEHaylock DNSnapp KRKansas GSSimmons PJLevesque JP. Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells..
Blood.
797A-797A.
2001
-
Prince HMWall DChapple PHaylock DNSeymour JFWolf MJanuscewicz HRichardson GRischin D. CliniMACS CD34-selected cells result in prolonged hemopoietic recovery following high-dose therapy..
Blood.
774A-774A.
2000
-
Haylock DNSimmons PJ. Isolation of primitive haemopoietic progenitors by prestimulation with HGF and incubation with 5-FU..
Blood.
71A-71A.
2000
-
Levesque JPTakamatsu YNilsson SKHaylock DNSimmons PJ. Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow..
Blood.
221A-221A.
2000
-
Haylock DNRohrsheim JMinster NWolfe SLMcKearn JPTo LBSimmons PJ. Combinations of chimeric receptor agonists provide potent stimulation of CD34+cells..
Blood.
556A-556A.
1999
-
Moore SLevesque JPHaylock DNMcDiarmid LSamels LTo LBSimmons PJHughes TP. Kit ligand as the sole stimulatory agent induces marked proliferation of CD34+ CML cells without a concomitant increase in adhesion..
Blood.
1746-1746.
1997
-
Haylock DNNuitta SLevesque JPTo LBSimmons PJ. Megakaryocyte growth and development factor (MGDF) preferentially promotes survival and is essential for maximal recruitment of adult bone marrow CD34+CD38- cells into division..
Blood.
2107-2107.
1997
-
Levesque JPHaylock DNTakamatsu YSimmons PJ. Regulation of beta 1 integrin affinity on haemopoietic progenitor cells: Role in homing and mobilisation..
Blood.
2123-2123.
1996
-
Ramshaw HSLi PHaylock DNHorsfall MJPeng HMercure LSimmons PJ. Increased recruitment of primitive hematopoietic progenitor cells by flt3 ligand leads to enhanced rates of retroviral transduction..
Experimental Hematology.
188-188.
1996
-
Lewis LDHaylock DNMoore STo LBJuttner CAHughes TP. Identification of normal primitive progenitors in blood and mobilised blood in chronic myeloid leukaemia..
Blood.
2085-2085.
1995
-
LEVESQUE JPHAYLOCK DNLEAVESLEY DIVADAS MASIMMONS PJ. INDUCTION BY CYTOKINES OF FIBRONECTIN RECEPTORS EXPRESSED BY CD34+ HEMATOPOIETIC-CELLS.
Experimental Hematology.
899-899.
1995
-
Juttner CATo LBHaylock DNDyson PGSimmons PJBayly JRawling CRawling THo JQKHorvath NDart GWHughes TPThorp D. Blood progenitor cells: Biologic and clinical issues.
Bone Marrow Transplantation.
1995
-
HUGHES TPWHITE DLHAYLOCK DNTURCZYNOWICZ SHUTCHINS CJTO LBJUTTNER CA. CYTOKINE SUPPORTED CULTURE OF CD34+ CELLS FROM AML PATIENTS RESULTS IN EXPANSION OF BOTH LEUKEMIC AND NORMAL PROGENITORS.
Blood.
A52-A52.
1994
-
TO LBROBERTS MMRAWLING CMROWLINGS PADYSON PGRAWLING TPHAYLOCK DNJUTTNER CA. ESTABLISHMENT OF A CLINICAL THRESHOLD CELL DOSE - CORRELATION BETWEEN CFU-GM AND DURATION OF APLASIA.
HEMATOPOIETIC STEM CELLS.
15-20.
1994
-
HAYLOCK DNTO LBDOWSE TLMAKINO STRIMBOLI SNIUTTA SJUTTNER CASIMMONS PJ. EXVIVO EXPANSION OF PURIFIED STEM CELLS.
HEMATOPOIETIC STEM CELLS.
291-301.
1994
-
HAYLOCK DNTO LBDOWSE TLMAKINO SJUTTNER CASIMMONS PJ. EX-VIVO EXPANSION AND MATURATION OF PERIPHERAL-BLOOD STEM AND PROGENITOR CELLS FOR TRANSPLANTATION.
Blood.
A483-A483.
1993
-
TO LBHAYLOCK DNDOWSE TSIMMONS PJASHMAN LKJUTTNER CA. PHENOTYPE AND PROLIFERATIVE CAPACITY OF PERIPHERAL-BLOOD CD34+ CELLS MOBILIZED BY 4 DIFFERENT PROTOCOLS.
Blood.
A493-A493.
1993
-
JUTTNER CAHAYLOCK DNTO LBDOWSE TLMAKINO SSIMMONS PJ. HEMATOPOIETIC CYTOKINES IN OUTPATIENT BONE-MARROW TRANSPLANTATION FOR CANCER-TREATMENT.
Journal of Leukocyte Biology.
39-39.
1993
-
TO LBHAYLOCK DNSIMMONS PJJUTTNER CA. EXVIVO EXPANSION OF PERIPHERAL-BLOOD CD34+ CELLS AND THEIR MATURATION TO FUNCTIONAL END CELLS - AN ADJUNCT TO HEMATOPOIETIC STEM-CELL TRANSPLANTATION.
Experimental Hematology.
753-753.
1992
-
JUTTNER CATO LBHAYLOCK DNBRANFORD ADYSON PKIMBER RJ. HEMATOPOIETIC RECONSTITUTION USING CIRCULATING AUTOLOGOUS STEM-CELLS COLLECTED IN VERY EARLY REMISSION FROM ACUTE NONLYMPHOBLASTIC LEUKEMIA.
Experimental Hematology.
465-465.
1986
-
TO LBDYSON PBRANFORD AHAYLOCK DNJUTTNER CA. IS THE CFU-MIX A BETTER INDICATOR OF MARROW REPOPULATING CAPACITY THAN THE CFU-GM.
Experimental Hematology.
438-438.
1986
-
HAYLOCK DNRICE AMJUTTNER CATO LBZOLA HBRADSTOCK KF. THE COMPETITION BETWEEN LEUKEMIC-CELLS AND PLATELETS FOR THE MONOCLONAL-ANTIBODY FMC8 - IMPLICATIONS FOR PURGING OF AUTOLOGOUS BONE-MARROW IN COMMON ALL.
Experimental Hematology.
465-465.
1986
-
TO LBRUSSELL JDYSON PMOORE SBRANFORD AHAYLOCK DNJUTTNER CA. INVITRO STUDIES ON CIRCULATING STEM-CELLS COLLECTED IN VERY EARLY REMISSION FROM ACUTE NONLYMPHOBLASTIC LEUKEMIA - LEUKEMIC CONTAMINATION AND PLURIPOTENT PROGENITOR-CELL CONTENT.
Australian and New Zealand Journal of Medicine.
124-124.
1986
-
Juttner CAHaylock DNTo LBKimber RJ. High levels of circulating myeloid progenitor cells in very early remission from acute non-lympho blastic leukemia.
Pathology.
363-364.
1984
Full text if available -
Haylock DNTo LBJuttner CAHavlocka DNKimber RJ. The collection and cryopreservation of peripheral blood stem cells from normal subjects and patients in remission from acute non-lymphocytic leukemia.
Pathology.
352-352.
1984
Full text if available -
HAYLOCK DNJEDANI JKJUTTNER CA. COLLECTION OF STEM-CELLS FROM PERIPHERAL-BLOOD IN EARLY REMISSION IN ACUTE NON-LYMPHOBLASTIC LEUKEMIA (ANLL).
Clinical and Experimental Pharmacology and Physiology.
543-543.
1982
-
HAYLOCK DNKIRKLAND MAJEDANI JKJUTTNER CA. HIGH-LEVEL OF CIRCULATING PROGENITOR CELLS IN EARLY REMISSION FROM ACUTE-LEUKEMIA.
Clinical and Experimental Pharmacology and Physiology.
544-545.
1982
-
Juttner CAHaylock DN. Repeated autologous bone marrow transplantation (BMT) necessary to produce an adequate megakaryocyte graft after intensive chemo/radiotherapy.
Pathology.
234-234.
1982
Full text if available -
Kirkland MAHaylock DNJedani JKJuttner CA. The anomalous effects of lithium and some known inhibitors of myelopoiesis on neutropenic bone marrow in culture.
Pathology.
233-233.
1982
Full text if available -
JUTTNER CAHAYLOCK DNTIDDY JA. HUMAN PROGENITOR-CELL (CFU-C) KINETICS FOLLOWING BONE-MARROW TRANSPLANTATION (BMT) FOR ACUTE MYELOID-LEUKEMIA (AML).
Clinical and Experimental Pharmacology and Physiology.
383-383.
1981
-
TIDDY JAHAYLOCK DNJUTTNER CA. SIMULTANEOUS DIFFERENTIAL STAINING OF PERMANENTLY FIXED HUMAN HEMATOPOIETIC COLONIES.
Clinical and Experimental Pharmacology and Physiology.
417-417.
1981
-
Berry JDGodara PLiovic PHaylock D. Evaluation of a groove bioreactor for stem cell expansion: Effects of inhibitory signalling.
Proceedings of the 19th Australasian Fluid Mechanics Conference, AFMC 2014.
2014