selected publications academic article Wette SGBirch NPSoop MZügel MMurphy RMLamb GDSmith HK. Expression of titin-linked putative mechanosensing proteins in skeletal muscle after power resistance exercise in resistance-trained men.. Journal of Applied Physiology. 2020 Full text if available Robinson KCulley DWaring SLamb GDEaston CCasarotto MGDulhunty AF. Peptide mimetic compounds can activate or inhibit cardiac and skeletal ryanodine receptors. Life Sciences. 260:1-16. 2020 Full text if available Lamb GDStephenson DG. Effect of nitrite on Ca 2+ movements and fatigue in muscle. The Journal of Physiology. 598:1641-1642. 2020 Full text if available Lamboley CRouffet DMDutka TMcKenna MJLamb G. Effects of high-intensity intermittent exercise on the contractile properties of human type I and type II skeletal muscle fibers. Journal of Applied Physiology. 128:1207-1216. 2020 Full text if available Ren XXu HBarker RGLamb GDMurphy RM. Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation. American Journal of Physiology: Cell Physiology. 318:C1083-C1091. 2020 Full text if available Ren XLamb GDMurphy RM. Distribution and activation of matrix metalloproteinase-2 in skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 317:C613-C625. 2019 Full text if available Watanabe DLamboley CRLamb GD. Effects of S‑glutathionylation on the passive force–length relationship in skeletal muscle fibres of rats and humans. Journal of Muscle Research and Cell Motility. 41. 2019 Full text if available Watanabe DDutka TLLamboley CRLamb GD. Skeletal muscle fibre swelling contributes to force depression in rats and humans: a mechanically-skinned fibre study. Journal of Muscle Research and Cell Motility. 40:343-351. 2019 Full text if available Xu HLamb GDMurphy RM. Changes in contractile and metabolic parameters of skeletal muscle as rats age from 3 to 12 months. Journal of Muscle Research and Cell Motility. 38:405-420. 2018 Full text if available Lamboley CXu HYDutka THanson EDHayes AViolet JAMurphy RLamb G. Effect of androgen deprivation therapy on the contractile properties of type I and type II skeletal muscle fibres in men with non-metastatic prostate cancer. Clinical and Experimental Pharmacology and Physiology. 45:146-154. 2018 Full text if available Lamb GDStephenson DG. Measurement of force and calcium release using mechanically skinned fibers from mammalian skeletal muscle. Journal of Applied Physiology. 125:1105-1127. 2018 Full text if available Xu HRen XLamb GDMurphy RM. Physiological and biochemical characteristics of skeletal muscles in sedentary and active rats. Journal of Muscle Research and Cell Motility. 39:1-16. 2018 Full text if available Wette SGSmith HKLamb GDMurphy RM. Characterization of muscle ankyrin repeat proteins in human skeletal muscle. American Journal of Physiology: Cell Physiology. 313:C327-C339. 2017 Full text if available Dutka TLMollica JPLamboley CRWeerakkody VCGreening DWPosterino GSMurphy RMLamb GD. S-nitrosylation and S-glutathionylation of Cys134 on troponin I have opposing competitive actions on Ca2+ sensitivity in rat fast-twitch muscle fibers. American Journal of Physiology: Cell Physiology. 312:C316-C327. 2017 Full text if available Lamboley CRWyckelsma VLMcKenna MJMurphy RMLamb GD. Ca2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans. The Journal of Physiology. 594:469-481. 2016 Full text if available Lamboley CRWyckelsma VLPerry BDMcKenna MJLamb GD. Effect of 23-day muscle disuse on sarcoplasmic reticulum Ca2+ properties and contractility in human type I and type II skeletal muscle fibers. Journal of Applied Physiology. 121:483-492. 2016 Full text if available Xu HFrankenberg NTLamb GDGooley PRStapleton DIMurphy RM. When phosphorylated at Thr(148), the beta(2)-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle. American Journal of Physiology: Cell Physiology. 311:C35-C42. 2016 Full text if available Lamboley CRWyckelsma VLDutka TLMcKenna MJMurphy RMLamb GD. Contractile properties and sarcoplasmic reticulum calcium content in typeI and typeII skeletal muscle fibres in active aged humans. The Journal of Physiology. 593:2499-2514. 2015 Full text if available Frankenberg NTLamb GDVissing KMurphy RM. Subcellular fractionation reveals HSP72 does not associate with SERCA in human skeletal muscle following damaging eccentric and concentric exercise. Journal of Applied Physiology. 116:1503-1511. 2014 Full text if available Dutka TLLamboley CRMurphy RMLamb GD. Acute effects of taurine on sarcoplasmic reticulum Ca2+ accumulation and contractility in human type I and type II skeletal muscle fibers. Journal of Applied Physiology. 117:797-805. 2014 Full text if available Lamboley CMurphy RMcKenna MLamb G. Sarcoplasmic reticulum Ca2+ uptake and leak properties, and SERCA isoform expression, in type I and type II fibres of human skeletal muscle. The Journal of Physiology. 592:1381-1395. 2014 Full text if available Frankenberg NLamb GOvergaard KMurphy RVissing K. Small heat shock proteins translocate to the cytoskeleton in human skeletal muscle following eccentric exercise independently of phosphorylation. Journal of Applied Physiology. 116:1463-1472. 2014 Full text if available Lamboley CRMurphy RMMcKenna MJLamb GD. Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres. The Journal of Physiology. 591:6053-6068. 2013 Full text if available Murphy RMLamb GD. Important considerations for protein analyses using antibody based techniques: down-sizing Western blotting up-sizes outcomes. The Journal of Physiology. 591:5823-5831. 2013 Full text if available Fajardo VAMcMeekin LBasic ALamb GDMurphy RMLeBlanc PJ. Isolation of Sarcolemmal Plasma Membranes by Mechanically Skinning Rat Skeletal Muscle Fibers for Phospholipid Analysis. Lipids. 48:421-430. 2013 Full text if available Murphy RDutka THorvath DBell JDelbridge LLamb G. Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle. The Journal of Physiology. 591:719-729. 2013 Full text if available Frankenberg NLarkins NTMurphy RMLamb GD. Influences of temperature, oxidative stress, and phosphorylation on binding of heat shock proteins in skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 303:C654-C665. 2012 Full text if available Dutka TLLamboley CRMcKenna MJMurphy RMLamb GD. Effects of carnosine on contractile apparatus Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in human skeletal muscle fibers. Journal of Applied Physiology. 112:728-736. 2012 Full text if available Mollica JPDutka TLMerry TLLamboley CRMcConell GKMcKenna MJMurphy RMLamb GD. S-Glutathionylation of troponin I (fast) increases contractile apparatus Ca2+sensitivity in fast-twitch muscle fibres of rats and humans. The Journal of Physiology. 590:1443-1463. 2012 Full text if available Frankenberg NLarkins NTMurphy RMLamb GD. Absolute amounts and diffusibility of HSP72, HSP25, and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of rat. American Journal of Physiology: Cell Physiology. 302:C228-C239. 2012 Full text if available Frankenberg NDutka TLVerburg ELarkins NHortemo KHLunde PKSejersted OMLamb GD. ROS-Mediated Decline in Maximum Ca2+-Activated Force in Rat Skeletal Muscle Fibers following In Vitro and In Vivo Stimulation. PLoS ONE. 7. 2012 Full text if available Murphy RMVissing KLatchman HLamboley CMcKenna MJOvergaard KLamb GD. Activation of skeletal muscle calpain-3 by eccentric exercise in humans does not result in its translocation to the nucleus or cytosol. Journal of Applied Physiology. 111:1448-1458. 2011 Full text if available Lamb GDWesterblad H. Acute effects of reactive oxygen and nitrogen species on the contractile function of skeletal muscle. The Journal of Physiology. 589:2119-2127. 2011 Full text if available Dutka TLMollica JPPosterino GSLamb GD. Modulation of contractile apparatus Ca2+sensitivity and disruption of excitation-contraction coupling byS-nitrosoglutathione in rat muscle fibres. The Journal of Physiology. 589:2181-2196. 2011 Full text if available Dutka TLMollica JPLamb GD. Differential effects of peroxynitrite on contractile protein properties in fast- and slow-twitch skeletal muscle fibers of rat. Journal of Applied Physiology. 110:705-716. 2011 Full text if available Murphy RMMollica JPBeard NAKnollmann BCLamb GD. Quantification of calsequestrin 2 (CSQ2) in sheep cardiac muscle and Ca2+-binding protein changes in CSQ2 knockout mice. American Journal of Physiology: Heart and Circulatory Physiology. 300:H595-H604. 2011 Full text if available Lamb GD. Mechanisms of excitation-contraction uncoupling relevant to activity-induced muscle fatigueThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.. Applied Physiology, Nutrition and Metabolism. 34:368-372. 2009 Full text if available Verburg EMurphy RMRichard ILamb GD. Involvement of calpains in Ca2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 296:C1115-C1122. 2009 Full text if available Murphy RMMollica JPLamb GD. Plasma membrane removal in rat skeletal muscle fibers reveals caveolin-3 hot-spots at the necks of transverse tubules. Experimental Cell Research. 315:1015-1028. 2009 Full text if available Murphy RMLamb GD. Endogenous Calpain-3 Activation Is Primarily Governed by Small Increases in Resting Cytoplasmic [Ca2+] and Is Not Dependent on Stretch. Journal of Biological Chemistry. 284:7811-7819. 2009 Full text if available Mollica JPOakhill JSLamb GDMurphy RM. Are genuine changes in protein expression being overlooked? Reassessing Western blotting. Analytical Biochemistry. 386:270-275. 2009 Full text if available Murphy RMLarkins NTMollica JPBeard NALamb GD. Calsequestrin content and SERCA determine normal and maximal Ca2+storage levels in sarcoplasmic reticulum of fast- and slow-twitch fibres of rat. The Journal of Physiology. 587:443-460. 2009 Full text if available Murphy RLamb G. Calpain-3 is activated following eccentric exercise.. Journal of Applied Physiology. 106:2068-2068. 2009 Full text if available Murphy RMDutka TLLamb GD. Hydroxyl radical and glutathione interactions alter calcium sensitivity and maximum force of the contractile apparatus in rat skeletal muscle fibres. The Journal of Physiology. 586:2203-2216. 2008 Full text if available Laver DRHonen BNLamb GDIkemoto N. A domain peptide of the cardiac ryanodine receptor regulates channel sensitivity to luminal Ca2+ via cytoplasmic Ca2+ sites. European Biophysics Journal. 37:455-467. 2008 Full text if available Dutka TLMurphy RMStephenson DGLamb GD. Chloride conductance in the transverse tubular system of rat skeletal muscle fibres: importance in excitation-contraction coupling and fatigue. The Journal of Physiology. 586:875-887. 2008 Full text if available Allen DGLamb GDWesterblad H. Impaired calcium release during fatigue. Journal of Applied Physiology. 104:296-305. 2008 Full text if available Allen DGLamb GDWesterblad H. Skeletal Muscle Fatigue: Cellular Mechanisms. Physiological Reviews. 88:287-332. 2008 Full text if available Murphy RMGoodman CAMcKenna MJBennie JLeikis MLamb GD. Calpain-3 is autolyzed and hence activated in human skeletal muscle 24 h following a single bout of eccentric exercise. Journal of Applied Physiology. 103:926-931. 2007 Full text if available Dutka TLLamb GD. Na+-K+ pumps in the transverse tubular system of skeletal muscle fibers preferentially use ATP from glycolysis. American Journal of Physiology: Cell Physiology. 293:C967-C977. 2007 Full text if available Dutka TLLamb GD. Transverse tubular system depolarization reduces tetanic force in rat skeletal muscle fibers by impairing action potential repriming. American Journal of Physiology: Cell Physiology. 292:C2112-C2121. 2007 Full text if available Murphy RMVerburg ELamb GD. Ca2+activation of diffusible and bound pools of μ-calpain in rat skeletal muscle. The Journal of Physiology. 576:595-612. 2006 Full text if available YANG ZIKEMOTO NLAMB GSTEELE D. Corrigendum to: The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes [Cardiovascular Research 70 (2006) 475–485]. Cardiovascular Research. 71:606-606. 2006 Full text if available Trinh HHLamb GD. MATCHING OF SARCOPLASMIC RETICULUM AND CONTRACTILE PROPERTIES IN RAT FAST- AND SLOW-TWITCH MUSCLE FIBRES. Clinical and Experimental Pharmacology and Physiology. 33:591-600. 2006 Full text if available Lamb GDStephenson DG. The Last Word: Point:Counterpoint authors respond to commentaries on “Lactic acid accumulation is an advantage/disadvantage during muscle activity”. Journal of Applied Physiology. 101:369-369. 2006 Full text if available YANG ZIKEMOTO NLAMB GSTEELE D. The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes. Cardiovascular Research. 70:475-485. 2006 Full text if available Verburg EDutka TLLamb GD. Long-lasting muscle fatigue: partial disruption of excitation-contraction coupling by elevated cytosolic Ca2+ concentration during contractions. American Journal of Physiology: Cell Physiology. 290:C1199-C1208. 2006 Full text if available Lamb GDStephenson DG. Point:Counterpoint: Lactic acid accumulation is an advantage/disadvantage during muscle activity. Journal of Applied Physiology. 100:1410-1412. 2006 Full text if available Murphy RMSnow RJLamb GD. μ-Calpain and calpain-3 are not autolyzed with exhaustive exercise in humans. American Journal of Physiology: Cell Physiology. 290:C116-C122. 2006 Full text if available Dutka TLCole LLamb GD. Calcium phosphate precipitation in the sarcoplasmic reticulum reduces action potential-mediated Ca2+ release in mammalian skeletal muscle. American Journal of Physiology: Cell Physiology. 289:C1502-C1512. 2005 Full text if available Verburg EMurphy RMStephenson DGLamb GD. Disruption of excitation-contraction coupling and titin by endogenous Ca2+-activated proteases in toad muscle fibres. The Journal of Physiology. 564:775-790. 2005 Full text if available Lamb GD. Rippling muscle disease may be caused by ?silent? action potentials in the tubular system of skeletal muscle fibers. Muscle and Nerve. 31:652-658. 2005 Full text if available Dulhunty AFCengia LYoung JPace SMHarvey PJLamb GDChan Y-NWimmer NToth ICasarotto MG. Functional implications of modifying RyR-activating peptides for membrane permeability. British Journal of Pharmacology. 144:743-754. 2005 Full text if available Murphy RMStephenson DGLamb GD. Effect of creatine on contractile force and sensitivity in mechanically skinned single fibers from rat skeletal muscle. American Journal of Physiology: Cell Physiology. 287:C1589-C1595. 2004 Full text if available Laver DRO'Neill ERLamb GD. Luminal Ca2+–regulated Mg2+ Inhibition of Skeletal RyRs Reconstituted as Isolated Channels or Coupled Clusters. Journal of General Physiology. 124:741-758. 2004 Full text if available Dutka TLLamb GD. Effect of low cytoplasmic [ATP] on excitation-contraction coupling in fast-twitch muscle fibres of the rat. The Journal of Physiology. 560:451-468. 2004 Full text if available Stephenson DGLamb GDPedersen TH. Intracellular Acidosis Enhances the Excitability of Working Muscle. Science. 305:1144-1147. 2004 Full text if available Nielsen OBØrtenblad NLamb GDStephenson DG. Excitability of the T-tubular system in rat skeletal muscle: roles of K+and Na+gradients and Na+-K+pump activity. The Journal of Physiology. 557:133-146. 2004 Full text if available Dutka TLLamb GD. Effect of Carnosine on Excitation–Contraction Coupling in Mechanically-Skinned Rat Skeletal Muscle. Journal of Muscle Research and Cell Motility. 25:203-213. 2004 Full text if available Posterino GSLamb GD. Effect of sarcoplasmic reticulum Ca2+ content on action potential-induced Ca2+ release in rat skeletal muscle fibres. The Journal of Physiology. 551:219-237. 2003 Full text if available Posterino GSCellini MALamb GD. Effects of oxidation and cytosolic redox conditions on excitation-contraction coupling in rat skeletal muscle. The Journal of Physiology. 547:807-823. 2003 Full text if available GREEN DPACE SCURTIS SMSAKOWSKA MLAMB GDDULHUNTY AFCASAROTTO MG. The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment. Biochemical Journal. 370:517-527. 2003 Full text if available Lamb GDPosterino GS. Effects of oxidation and reduction on contractile function in skeletal muscle fibres of the rat. The Journal of Physiology. 546:149-163. 2003 Full text if available Lamb GD. Excitation-contraction coupling and fatigue mechanisms in skeletal muscle: Studies with mechanically skinned fibres. Journal of Muscle Research and Cell Motility. 23:81-91. 2002 Full text if available Lamb GD. Voltage-sensor control of Ca2+ release in skeletal muscle: insights from skinned fibers. Frontiers in Bioscience. 7:d834-d834. 2002 Full text if available Laver DRLenz GKELamb GD. Regulation of the calcium release channel from rabbit skeletal muscle by the nucleotides ATP, AMP, IMP and adenosine. The Journal of Physiology. 537:763-778. 2001 Full text if available Laver DRLenz GKELamb GD. Regulation of the calcium release channel from rabbit skeletal muscle by the nucleotides ATP, AMP, IMP and adenosine. The Journal of Physiology. 537:763-778. 2001 Full text if available Lamb GDPosterino GSYamamoto TIkemoto N. Effects of a domain peptide of the ryanodine receptor on Ca2+ release in skinned skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 281:C207-C214. 2001 Full text if available Lamb GDPosterino GSYamamoto TIkemoto N. Effects of a domain peptide of the ryanodine receptor on Ca2+ release in skinned skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 281:C207-C214. 2001 Posterino GDutka TLamb G. L (+)-lactate does not affect twitch and tetanic responses in mechanically skinned mammalian muscle fibres. Pfluegers Archiv: European journal of physiology. 442:197-203. 2001 Full text if available Lamb GDCellini MAStephenson DG. Different Ca 2+ releasing action of caffeine and depolarisation in skeletal muscle fibres of the rat. The Journal of Physiology. 531:715-728. 2001 Full text if available Blazev RHussain MBakker AJHead SILamb GD. Effects of the PKA inhibitor H-89 on excitation-contraction coupling in skinned and intact skeletal muscle fibres. Journal of Muscle Research and Cell Motility. 22:277-286. 2001 Full text if available Lamb GDLaver DRStephenson DG. Questions about Adaptation in Ryanodine Receptors. Journal of General Physiology. 116:883-890. 2000 Full text if available Lamb GDEl-Hayek RIkemoto NStephenson DG. Effects of dihydropyridine receptor II-III loop peptides on Ca2+ release in skinned skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 279:C891-C905. 2000 Full text if available Posterino GSLamb GDStephenson DG. Twitch and tetanic force responses and longitudinal propagation of action potentials in skinned skeletal muscle fibres of the rat. The Journal of Physiology. 527:131-137. 2000 Full text if available Laver DREager KRTaoube LLamb GD. Effects of Cytoplasmic and Luminal pH on Ca2+ Release Channels from Rabbit Skeletal Muscle. Biophysical Journal. 78:1835-1851. 2000 Full text if available Dutka TLLamb GD. Effect of lactate on depolarization-induced Ca2+ release in mechanically skinned skeletal muscle fibers. American Journal of Physiology: Cell Physiology. 278:C517-C525. 2000 Full text if available Blazev RLamb GD. Adenosine inhibits depolarization-induced Ca2+ release in mammalian skeletal muscle. Muscle and Nerve. 22:1674-1683. 1999 Full text if available Blazev RLamb GD. Low [ATP] and elevated [Mg2+] reduce depolarization-induced Ca2+release in rat skinned skeletal muscle fibres. The Journal of Physiology. 520:203-215. 1999 Full text if available Lamb GDCellini MA. High intracellular [Ca2+] alters sarcoplasmic reticulum function in skinned skeletal muscle fibres of the rat. The Journal of Physiology. 519:815-827. 1999 Full text if available Laver DREager KRTaoube LLamb GD. Regulation of the skeletal muscle calcium release channel (RyR1) by luminal and cytosolic pH.. Biophysical Journal. 76:A303-A303. 1999 Coonan JRLamb GD. Effect of transverse-tubular chloride conductance on excitability in skinned skeletal muscle fibres of rat and toad. The Journal of Physiology. 509:551-564. 1998 Full text if available Laver DRLamb GD. Inactivation of Ca2+ Release Channels (Ryanodine Receptors RyR1 and RyR2) with Rapid Steps in [Ca2+] and Voltage. Biophysical Journal. 74:2352-2364. 1998 Full text if available Coonan JRLamb GD. Effect of chloride on Ca 2+ release from the sarcoplasmic reticulum of mechanically skinned skeletal muscle fibres. Pfluegers Archiv: European journal of physiology. 435:720-730. 1998 Full text if available STEPHENSON DGLAMB GDSTEPHENSON GMM. Events of the excitation-contraction-relaxation (E-C-R) cycle in fast- and slow-twitch mammalian muscle fibres relevant to muscle fatigue. Acta Physiologica. 162:229-245. 1998 Full text if available Posterino GSLamb GD. Effect of nifedipine on depolarization-induced force responses in skinned skeletal muscle fibres of rat and toad. Journal of Muscle Research and Cell Motility. 19:53-65. 1998 Full text if available Posterino GSLamb GD. Investigation of the effect of inositol trisphosphate in skinned skeletal muscle fibres with functional excitation-contraction coupling. Journal of Muscle Research and Cell Motility. 19:67-74. 1998 Full text if available Laver DROwen VJJunankar PRTaske NLDulhunty AFLamb GD. Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia. Biophysical Journal. 73:1913-1924. 1997 Full text if available Lamb GDStephenson DG. Oxidation effects in fatigue: unphysiological responses to “depolarization” in skinned muscle fibers. Journal of Applied Physiology. 82:2054-2056. 1997 Full text if available Owen VJLamb GDStephenson DGFryer MW. Relationship between depolarization-induced force responses and Ca2+ content in skeletal muscle fibres of rat and toad.. The Journal of Physiology. 498:571-586. 1997 Full text if available Brotto MAPNosek TMLamb GDStephenson DG. Hydrogen peroxide disrupts Ca2+ release from the sarcoplasmic reticulum of rat skeletal muscle fibers (multiple letters). Journal of Applied Physiology. 82:2054-2056. 1997 Owen VJTaske NLLamb GD. Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia. American Journal of Physiology: Cell Physiology. 272:C203-C211. 1997 Full text if available Owen VJTaske NLLamb GD. Reduced Mg2+ inhibition of Ca2+ release in muscle fibers of pigs susceptible to malignant hyperthermia. American Journal of Physiology: Cell Physiology. 272:C203-C211. 1997 LAMB GD. Ryanodine receptor 'adaptation': A flash in the pan?. Journal of Muscle Research and Cell Motility. 18:611-616. 1997 Full text if available Posterino GSLamb GD. Effects of reducing agents and oxidants on excitation-contraction coupling in skeletal muscle fibres of rat and toad.. The Journal of Physiology. 496:809-825. 1996 Full text if available Lamb GDStephenson DG. Effects of FK506 and rapamycin on excitation-contraction coupling in skeletal muscle fibres of the rat.. The Journal of Physiology. 494:569-576. 1996 Full text if available Owen VJLamb GDStephenson DG. Effect of low [ATP] on depolarization-induced Ca2+ release in skeletal muscle fibres of the toad.. The Journal of Physiology. 493:309-315. 1996 Full text if available Owen VJLamb GDStephenson DG. Low [ATP] reduces depolarization-induced calcium release in skeletal muscle fibers. Biophysical Journal. 70:MPO80-MPO80. 1996 Bakker AJLamb GDStephenson DG. The effect of 2,5-di-(tert-butyl)-1,4-hydroquinone on force responses and the contractile apparatus in mechanically skinned muscle fibres of the rat and toad. Journal of Muscle Research and Cell Motility. 17:55-67. 1996 Full text if available Lamb GDJunankar PRStephenson DG. Raised intracellular [Ca2+] abolishes excitation-contraction coupling in skeletal muscle fibres of rat and toad.. The Journal of Physiology. 489:349-362. 1995 Full text if available STEPHENSON DGLAMB GDSTEPHENSON GMMFRYER MW. STORAGE OF CA2+ IN THE SARCOPLASMIC-RETICULUM AND ENDOGENOUS MODIFIERS OF E-C COUPLING IN SKELETAL-MUSCLE FIBERS FROM CANE TOAD AND RAT. The Journal of Physiology. 487P:S8-S8. 1995 Lamb GDStephenson DG. Activation of ryanodine receptors by flash photolysis of caged Ca2+. Biophysical Journal. 68:946-948. 1995 Full text if available Fryer MWOwen VJLamb GDStephenson DG. Effects of creatine phosphate and P(i) on Ca2+ movements and tension development in rat skinned skeletal muscle fibres.. The Journal of Physiology. 482:123-140. 1995 Full text if available Stephenson DGLamb GDStephenson GMMFryer MW. Mechanisms of Excitation-Contraction Coupling Relevant to Skeletal Muscle Fatigue. Advances in Experimental Medicine and Biology. 384:45-56. 1995 Full text if available Lamb GDStephenson DG. Effects of intracellular pH and [Mg2+] on excitation-contraction coupling in skeletal muscle fibres of the rat.. The Journal of Physiology. 478:331-339. 1994 Full text if available Lamb GFryer MStephenson D. Ca(2+)-induced Ca2+ release in response to flash photolysis. Science. 263:986-988. 1994 Full text if available BAKKER AJLAMB GDSTEPHENSON DG. THE EFFECT OF 2,5-DI-(TERT-BUTYL)-1,4-BENZOHYDROQUINONE ON THE CONTRACTILE APPARATUS AND FORCE RESPONSES IN SKINNED MUSCLE-FIBERS OF THE RAT. Biophysical Journal. 66:A90-A90. 1994 Lamb GDPosterino GSStephenson DG. Effects of heparin on excitation-contraction coupling in skeletal muscle toad and rat.. The Journal of Physiology. 474:319-329. 1994 Full text if available Lamb GD. Ca2+ inactivation, Mg2+ inhibition and malignant hyperthermia. Journal of Muscle Research and Cell Motility. 14:554-556. 1993 Full text if available Lamb GDStephenson DGStienen GJ. Effects of osmolality and ionic strength on the mechanism of Ca2+ release in skinned skeletal muscle fibres of the toad.. The Journal of Physiology. 464:629-648. 1993 Full text if available STEPHENSON DGLAMB GD. VISUALIZATION OF THE TRANSVERSE TUBULAR SYSTEM IN ISOLATED INTACT AND IN MECHANICALLY SKINNED MUSCLE-FIBERS OF THE CANE TOAD BY CONFOCAL LASER SCANNING MICROSCOPY. The Journal of Physiology. 459:P15-P15. 1993 LAMB GDSTEPHENSON DG. IMPORTANCE OF MG-2+ IN EXCITATION-CONTRACTION COUPLING IN SKELETAL-MUSCLE. Physiology. 7:270-274. 1992 Lamb GD. DHP receptors and excitation-contraction coupling. Journal of Muscle Research and Cell Motility. 13:394-405. 1992 Full text if available Lamb GDRecupero EStephenson DG. Effect of myoplasmic pH on excitation-contraction coupling in skeletal muscle fibres of the toad.. The Journal of Physiology. 448:211-224. 1992 Full text if available Lamb GDStephenson DG. Control of Calcium Release from the Sarcoplasmic Reticulum. Advances in human genetics. 311:289-303. 1992 Full text if available Lamb GDStephenson DG. Excitation-contraction coupling in skeletal muscle fibres of rat and toad in the presence of GTP gamma S.. The Journal of Physiology. 444:65-84. 1991 Full text if available Lamb GD. Effect of Bay K8644 on Ca2+ channel gating charge. Biophysical Journal. 60:979-979. 1991 Full text if available LAMB GD. Ca2+ channels or voltage sensors?. Nature. 352:113-113. 1991 Full text if available Lamb GDStephenson DG. Effect of Mg2+ on the control of Ca2+ release in skeletal muscle fibres of the toad.. The Journal of Physiology. 434:507-528. 1991 Full text if available Lamb GDStephenson DG. Calcium release in skinned muscle fibres of the toad by transverse tubule depolarization or by direct stimulation.. The Journal of Physiology. 423:495-517. 1990 Full text if available Lamb GDStephenson DG. Control of calcium release and the effect of ryanodine in skinned muscle fibres of the toad.. The Journal of Physiology. 423:519-542. 1990 Full text if available LAMB GDSTEPHENSON DG. ACTIVATION AND REDUCTION OF CALCIUM RELEASE IN SKINNED MUSCLE-FIBERS FROM THE CANE TOAD. The Journal of Physiology. 418:P70-P70. 1989 Gage PWLamb GDWakefield BT. Transient and persistent sodium currents in normal and denervated mammalian skeletal muscle.. The Journal of Physiology. 418:427-439. 1989 Full text if available Fryer MWLamb GDNeering IR. The action of ryanodine on rat fast and slow intact skeletal muscles.. The Journal of Physiology. 414:399-413. 1989 Full text if available Lamb GDHopkinson KCDenborough MA. Calcium currents and asymmetric charge movement in malignant hyperpyrexia. Muscle and Nerve. 12:135-140. 1989 Full text if available Gage PWDulhunty AFLamb GDWakefield BT. Effects of denervation on excitation - contraction coupling in mammalian muscle. Fernstrom Foundation Series. 13:405-412. 1989 Field ACHill CLamb GD. Asymmetric charge movement and calcium currents in ventricular myocytes of neonatal rat.. The Journal of Physiology. 406:277-297. 1988 Full text if available Lamb GDWalsh T. Calcium currents, charge movement and dihydropyridine binding in fast- and slow-twitch muscles of rat and rabbit.. The Journal of Physiology. 393:595-617. 1987 Full text if available Dulhunty AFGage PWLamb GD. Potassium contractures and asymmetric charge movement in extensor digitorum longus and soleus muscles from thyrotoxic rats. Journal of Muscle Research and Cell Motility. 8:289-296. 1987 Full text if available Lamb GD. Asymmetric charge movement in polarized and depolarized muscle fibres of the rabbit.. The Journal of Physiology. 383:349-367. 1987 Full text if available Lamb GD. Asymmetric charge movement in contracting muscle fibres in the rabbit.. The Journal of Physiology. 376:63-83. 1986 Full text if available Lamb GD. Components of charge movement in rabbit skeletal muscle: the effect of tetracaine and nifedipine.. The Journal of Physiology. 376:85-100. 1986 Full text if available Dulhunty AFGage PWLamb GD. Differential effects of thyroid hormone on T-tubules and terminal cisternae in rat muscles: An electrophysiological and morphometric analysis. Journal of Muscle Research and Cell Motility. 7:225-236. 1986 Full text if available Lamb GD. Generalization of the three-microelectrode voltage clamp technique to allow unequal electrode spacings. Journal of Electrophysiological Techniques. 13:255-264. 1986 Lamb GD. Tactile discrimination of textured surfaces: peripheral neural coding in the monkey.. The Journal of Physiology. 338:567-587. 1983 Full text if available Lamb GD. Tactile discrimination of textured surfaces: psychophysical performance measurements in humans.. The Journal of Physiology. 338:551-565. 1983 Full text if available Johnson KOLamb GD. Neural mechanisms of spatial tactile discrimination: neural patterns evoked by braille-like dot patterns in the monkey.. The Journal of Physiology. 310:117-144. 1981 Full text if available conference paper Kennedy PMcLean CLamb GMurphy R. Calpain-3 stability following delays in freezing skeletal muscle biopsy samples-stablishing an optimal time frame for accurate interpretation. Neuromuscular Disorders. S144-S144. 2017 Lamb G. Muscle fatigue. 1-1. 2006 Pedersen THNielsen OBLamb GDStephenson DG. Intracellular acidosis enhances T-system excitability in depolarized skeletal muscles. The FASEB Journal. A1115-A1115. 2005 Honen BNLamb GDLaver DRIkemoto N. Aberrant calcium release underlying sudden cardiac death probed with RyR domain peptides. Biophysical Journal. 92A-92A. 2005 Lamb G. Muscle fatigue and H+ : firend or foe?. Exercise, Muscle and Metabolism Meeting. 1-1. 2005 Laver DRLamb GD. Regulation of single and coupled RyRs in bilayers by luminal Ca2+. Biophysical Journal. 383A-383A. 2005 Lamb G. EC coupling in skeletal muscle : implications for fatigue. 2nd Australian Health & Medical Research Congress. 1-1. 2004 Murphy RStephenson DLamb G. Effect of creatine on contractile force and sensitivity in mechanically-skinned single fibers from rat skeletal muscle.. Proceedings of the Australian Physiological Society, 34. 12-12. 2004 O'Neill ELamb GLaver D. Magnesium inhibition of skeletal RyRs modified by DIDS, ryanodine and ATP. Biophysical Journal. 108A-108A. 2003 Kobayashi SYamamoto TLaver DRLamb GDIkemoto N. RyR1 and RyR2 seem to share a common mechanism of cytoplasmic domain-mediated channel regulation: peptide probe studies. Biophysical Journal. 427A-427A. 2003 Lamb G. AP-induced Ca2+ release at different SR Ca2+ content. Gordon Research Conference on Excitation Contraction Coupling in Muscle. 1-1. 2003 Lamb G. All you ever wanted to know about skinned fibres. Curtin Conference on Muscle. 1-1. 2003 Nielsen OBOrtenblad NLamb GDStephenson DG. Role of the Na+-K+ pump in maintaining T-tubular excitability in rat skeletal muscle. The Journal of Physiology. 80P-81P. 2002 Lamb G. EC coupling, oxidation and muscle fatigue : Insights from skinned fibres. European Muscle Society Conference. 1-1. 2002 Lamb G. Voltage-sensor control of Ca2+ release in skeletal muscle : Insights from MH and RyR DP4. International Union of Physiological Societies Satellite Conference on Excitation-contraction coupling in skeletal and cardiac muscle. 1-1. 2001 Lamb G. Excitation-Contraction Coupling In Skeletal Muscle: Comparisons With Cardiac Muscle. Clinical and Experimental Pharmacology and Physiology. 216-224. 2000 Full text if available Lamb GD. Excitation-contraction coupling and fatigue in skeletal muscle. BIOCHEMISTRY OF EXERCISE X. 99-114. 1999 Lamb GDRecupero EStephenson DG. Effect of pH on excitation-contraction coupling in isolated skeletal muscle of toad. The Journal of Physiology. P263-P263. 1992 editorial article Lamb GD. Calpains in muscle: selective and protective?. The Journal of Physiology. 582:897-897. 2007 Full text if available Lamb GD. Store-operated Ca2+release in skeletal muscle: tailored for a specialized system. The Journal of Physiology. 583:1-1. 2007 Full text if available letter Wette SGSmith HKLamb GDMurphy RM. Reply to “Letter to the editor: Comments on Wette et al. (2017): ‘Characterization of muscle ankyrin repeat proteins in human skeletal muscle’”. American Journal of Physiology: Cell Physiology. C471-C472. 2017 Full text if available Dutka TLMollica JPPosterino GSLamb GD. Potential problems and pitfalls with the use of S-nitrosoglutathione and other S-nitrosothiols in physiology-oriented basic science Reply. Journal of Physiology: Paris. 6249-6250. 2012 Full text if available Lamb GDMurphy RMStephenson DG. On the localization of ClC-1 in skeletal muscle fibers. Journal of General Physiology. 327-329. 2011 Full text if available Murphy RMLamb GD. Calpain-3 is activated following eccentric exercise. Journal of Applied Physiology. 2068-2068. 2009 Full text if available
principal investigator on Calcium cycling and heat generation in skeletal muscle fibres awarded by Australian Research Council (ARC) - Discovery Projects 2018 - 2021 Molecular Basis of Ca2+-Dependent Disruption of EC-coupling and Weakness in Skeletal Muscle awarded by National Health and Medical Research Council (NHMRC) - Project Grants 2015 - 2018 Physiological and Pathological Effects of Oxidation on Contractile Function in Skeletal Muscle awarded by National Health and Medical Research Council (NHMRC) - Project Grants 2013 - 2016 Uncoupled Research Fellowship awarded by National Health and Medical Research Council (NHMRC) - Research Fellowships 2009 - 2015 Calpain regulation in skeletal muscle awarded by National Health and Medical Research Council (NHMRC) - Project Grants 2010 - 2012 Mechanisms involved in skeletal muscle contraction in health, exercise and disease awarded by National Health and Medical Research Council (NHMRC) - Project Grants 2009 - 2011 Understanding how chloride channels function and their role in muscle fatigue and disease awarded by National Health and Medical Research Council (NHMRC) 2009 - 2011 Calcium-dependent proteases in muscle damage and disease awarded by National Health and Medical Research Council (NHMRC) - Project Grants 2007 - 2010
investigator on 2009 NHMRC Equipment Grant awarded by National Health and Medical Research Council (NHMRC) - Equipment Grants 2009 - 2010 2008 NHMRC Equipment Grant awarded by National Health and Medical Research Council (NHMRC) - Equipment Grants 2009