selected publications
-
academic article
-
Thilakasiri PHuynh JPoh ARTan CWNero TLTran KParslow ACAfshar-Sterle SBaloyan DHannan NJBuchert MScott AMGriffin MDWHollande FParker MWPutoczki TLErnst MChand AL. Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
EMBO Molecular Medicine.
11.
2019
Full text if available -
Huynh JChand AGough DErnst M. Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map.
Nature Reviews: Cancer.
19:82-96.
2019
Full text if available -
Schmidt SSchumacher NSchwarz JTangermann SKenner LSchlederer MSibilia MLinder MAltendorf-Hofmann AKnösel TGruber ESOberhuber GBolik JRehman ASinha ALokau JArnold PCabron ASZunke FBecker-Pauly CPreaudet ANguyen PHuynh JAfshar-Sterle SChand ALWestermann JDempsey PJGarbers CSchmidt-Arras DRosenstiel PPutoczki TErnst MRose-John S. ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
Journal of Experimental Medicine.
215:1205-1225.
2018
Full text if available -
Aw JScholz GMHuq NLHuynh JO'Brien-Simpson NMReynolds EC. Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14.
Cellular Microbiology.
20:1-13.
2018
Full text if available -
Huynh JScholz GMAw JReynolds EC. Interferon regulatory Factor 6 promotes Keratinocyte differentiation in response to Porphyromonas gingivalis.
Infection and Immunity.
85.
2017
Full text if available -
Huynh JEtemadi NHollande FErnst MBuchert M. The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.
Seminars in Cancer Biology.
45:13-22.
2017
Full text if available -
Huynh JScholz GMAw JKwa MQAchuthan AHamilton JAReynolds EC. IRF6 regulates the expression of IL-36γ by human oral epithelial cells in response to Porphyromonas gingivalis.
Journal of Immunology.
196:2230-2238.
2016
Full text if available -
Kwa MQHuynh JReynolds ECHamilton JAScholz GM. Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions.
Cellular Signalling.
27:1509-1516.
2015
Full text if available -
Kwa MQNguyen THuynh JRamnath DDe Nardo DLam PYReynolds ECHamilton JASweet MJScholz GM. Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells.
Journal of Biological Chemistry.
289:19758-19768.
2014
Full text if available -
Kwa MQHuynh JAw JZhang LNguyen TReynolds ECSweet MJHamilton JAScholz GM. Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.
Journal of Biological Chemistry.
289:31077-31087.
2014
Full text if available -
Hamilton JALacey DCTurner Ade Kok BHuynh JScholz GM. Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF.
PLoS ONE.
7:e45853-e45853.
2012
Full text if available -
Huynh JKwa MQCook ADHamilton JAScholz GM. CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages.
Cellular Signalling.
24:1753-1761.
2012
Full text if available
-
Thilakasiri PHuynh JPoh ARTan CWNero TLTran KParslow ACAfshar-Sterle SBaloyan DHannan NJBuchert MScott AMGriffin MDWHollande FParker MWPutoczki TLErnst MChand AL. Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
EMBO Molecular Medicine.
11.
2019
-
conference paper
-
Huynh JChand AErnst M. IL-11 as a therapeutic target to treat colorectal cancer.
Cancer Research.
2018
Full text if available
-
Huynh JChand AErnst M. IL-11 as a therapeutic target to treat colorectal cancer.
Cancer Research.
2018