selected publications
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academic article
- Thilakasiri PHuynh JPoh ARTan CWNero TLTran KParslow ACAfshar-Sterle SBaloyan DHannan NJBuchert MScott AMGriffin MDWHollande FParker MWPutoczki TLErnst MChand AL. Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth. EMBO Molecular Medicine. 11. 2019
- Huynh JChand AGough DErnst M. Therapeutically exploiting STAT3 activity in cancer — using tissue repair as a road map. Nature Reviews: Cancer. 19:82-96. 2019
- Schmidt SSchumacher NSchwarz JTangermann SKenner LSchlederer MSibilia MLinder MAltendorf-Hofmann AKnösel TGruber ESOberhuber GBolik JRehman ASinha ALokau JArnold PCabron ASZunke FBecker-Pauly CPreaudet ANguyen PHuynh JAfshar-Sterle SChand ALWestermann JDempsey PJGarbers CSchmidt-Arras DRosenstiel PPutoczki TErnst MRose-John S. ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling. Journal of Experimental Medicine. 215:1205-1225. 2018
- Aw JScholz GMHuq NLHuynh JO'Brien-Simpson NMReynolds EC. Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14. Cellular Microbiology. 20:1-13. 2018
- Huynh JScholz GMAw JReynolds EC. Interferon regulatory Factor 6 promotes Keratinocyte differentiation in response to Porphyromonas gingivalis. Infection and Immunity. 85:1-12. 2017
- Huynh JEtemadi NHollande FErnst MBuchert M. The JAK/STAT3 axis: A comprehensive drug target for solid malignancies. Seminars in Cancer Biology. 45:13-22. 2017
- Huynh JScholz GMAw JKwa MQAchuthan AHamilton JAReynolds EC. IRF6 regulates the expression of IL-36γ by human oral epithelial cells in response to Porphyromonas gingivalis. Journal of Immunology. 196:2230-2238. 2016
- Kwa MQHuynh JReynolds ECHamilton JAScholz GM. Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions. Cellular Signalling. 27:1509-1516. 2015
- Kwa MQNguyen THuynh JRamnath DDe Nardo DLam PYReynolds ECHamilton JASweet MJScholz GM. Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry. 289:19758-19768. 2014
- Kwa MQHuynh JAw JZhang LNguyen TReynolds ECSweet MJHamilton JAScholz GM. Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation. Journal of Biological Chemistry. 289:31077-31087. 2014
- Hamilton JALacey DCTurner Ade Kok BHuynh JScholz GM. Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF. PLoS ONE. 7:e45853-e45853. 2012
- Huynh JKwa MQCook ADHamilton JAScholz GM. CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages. Cellular Signalling. 24:1753-1761. 2012