Cancer Research
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Overview
publication venue for
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Frizzled-7 is required for Wnt signaling in gastric tumors with and without APC mutations.
79:970-981.
2019
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Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism.
78:1293-1307.
2018
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Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cells..
78:2925-2938.
2018
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An Accessible Proteogenomics Informatics Resource for Cancer Researchers.
77:e43-e46.
2017
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HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2 + Tumors.
77:2594-2606.
2017
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Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
76:2277-2287.
2016
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The Biodistribution and Immune Suppressive Effects of Breast Cancer-Derived Exosomes.
76:6816-6827.
2016
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The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.
76:4236-4248.
2016
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Correction: HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial–Mesenchymal Transition.
75:2401-2401.
2015
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BMP4 Inhibits Breast Cancer Metastasis by Blocking Myeloid-Derived Suppressor Cell Activity.
74:5091-5102.
2014
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Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
74:3238-3247.
2014
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Metabolic Vulnerabilities in Endometrial Cancer.
74:5832-5845.
2014
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Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling.
74:5019-5031.
2014
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Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment.
74:4470-4481.
2014
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The Emerging Role of Immunosurveillance in Dictating Metastatic Spread in Breast Cancer.
73:5852-5857.
2013
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SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.
73:725-735.
2013
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The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells.
73:1180-1189.
2013
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Abstract P3-10-09: Peptide-based molecular targeting of inflammatory breast cancer..
72:P3-10-09-P3-10-09.
2012
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Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche.
72:3906-3911.
2012
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Abstract LB-308: Combination of CTx-0294945 a highly selective inhibitor of focal adhesion kinase with bevacizumab in pre-clinical models of breast cancer.
72:LB-308-LB-308.
2012
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Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy.
72:1694-1704.
2012
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Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer.
72:1199-1209.
2012
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Ovarian Cancer Risk Associated with Inherited Inflammation-Related Variants.
72:1064-1069.
2012
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Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy.
72:2924-2930.
2012
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MYB is essential for mammary tumorigenesis.
71:7029-7037.
2011
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Abstract 1469: Mechanisms of oncostatin M (OSM)-mediated breast cancer metastasis to bone: Evidence for a role in osteoclastogenesis.
71:1469-1469.
2011
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PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.
71:3709-3719.
2011
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Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer.
70:5901-5911.
2010
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Altered Dynamics of Intestinal Cell Maturation in Apc1638N/+ Mice.
70:5348-5357.
2010
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Correction: An A13 Repeat within the 3'-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression.
70:1275-1275.
2010
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Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction.
70:609-620.
2010
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PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab (vol 68, pg 1953, 2008).
69:9156-9156.
2009
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Correction: Parathyroid Hormone-Related Protein Protects against Mammary Tumor Emergence and Is Associated with Monocyte Infiltration in Ductal Carcinoma In situ.
69:8832-8832.
2009
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An A13 Repeat within the 3'-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression.
69:7811-7818.
2009
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Parathyroid Hormone-Related Protein Protects against Mammary Tumor Emergence and Is Associated with Monocyte Infiltration in Ductal Carcinoma In situ.
69:7473-7479.
2009
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The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis.
69:7430-7438.
2009
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Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines.
69:6033-6041.
2009
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Breast Cancer Lung Metastasis Requires Expression of Chemokine Receptor CCR4 and Regulatory T Cells.
69:5996-6004.
2009
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Correction: Article on Vaccination Reveals a Long Dominant CTL Epitope.
69:4553-4553.
2009
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ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adduct forming treatments in HL-60 cells.
69.
2009
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Bmp4 controls breast cancer metastasis by modulating CD11b(+)Gr1(+) cells in vivo.
69.
2009
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The Steroid Receptor Coactivator-1 Regulates Twist Expression and Promotes Breast Cancer Metastasis.
69:3819-3827.
2009
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The role of c-Myb in tumorigenesis and mammary gland development.
69.
2009
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A Long, Naturally Presented Immunodominant Epitope from NY-ESO-1 Tumor Antigen: Implications for Cancer Vaccine Design.
69:1046-1054.
2009
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Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth.
68:9157-9166.
2008
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Correction: Prediction of Response to Cetuximab.
68:6859-6859.
2008
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Defective Claudin-7 Regulation by Tcf-4 and Sox-9 Disrupts the Polarity and Increases the Tumorigenicity of Colorectal Cancer Cells.
68:4258-4268.
2008
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The Nuclear Receptor Coactivator Amplified in Breast Cancer-1 Is Required for Neu (ErbB2/HER2) Activation, Signaling, and Mammary Tumorigenesis in Mice.
68:3697-3706.
2008
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The Regulatory T Cell-Associated Transcription Factor FoxP3 Is Expressed by Tumor Cells.
68:3001-3009.
2008
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PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab.
68:1953-1961.
2008
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Genetic Screening Reveals an Essential Role of p27kip1 in Restriction of Breast Cancer Progression.
67:8032-8042.
2007
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Genetic Ablation of the Amplified-in-Breast Cancer 1 Inhibits Spontaneous Prostate Cancer Progression in Mice.
67:5965-5975.
2007
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TRAIL Induces Receptor-Interacting Protein 1–Dependent and Caspase-Dependent Necrosis-Like Cell Death under Acidic Extracellular Conditions.
67:218-226.
2007
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HOXB7, a Homeodomain Protein, Is Overexpressed in Breast Cancer and Confers Epithelial-Mesenchymal Transition.
66:9527-9534.
2006
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EPHB4 and Survival of Colorectal Cancer Patients.
66:8943-8948.
2006
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Transduction of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand into Hematopoietic Cells Leads to Inhibition of Syngeneic Tumor Growth In vivo.
66:6304-6311.
2006
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Doxorubicin-DNA Adducts Induce a Non-Topoisomerase II–Mediated Form of Cell Death.
66:4863-4871.
2006
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Papillomavirus E2 Protein Induces Expression of the Matrix Metalloproteinase-9 via the Extracellular Signal-Regulated Kinase/Activator Protein-1 Signaling Pathway.
65:11613-11621.
2005
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Mechanisms of Inactivation of the Receptor Tyrosine Kinase EPHB2 in Colorectal Tumors.
65:10170-10173.
2005
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Mice Lacking the Amplified in Breast Cancer 1/Steroid Receptor Coactivator-3 Are Resistant to Chemical Carcinogen–Induced Mammary Tumorigenesis.
65:7993-8002.
2005
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Apoptin Nuclear Accumulation Is Modulated by a CRM1-Recognized Nuclear Export Signal that Is Active in Normal but not in Tumor Cells.
65:7059-7064.
2005
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Concurrent Binding of Anti-EphA3 Antibody and Ephrin-A5 Amplifies EphA3 Signaling and Downstream Responses: Potential as EphA3-Specific Tumor-Targeting Reagents.
65:6745-6754.
2005
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Oncogenic K-RAS Is Required to Maintain Changes in Cytoskeletal Organization, Adhesion, and Motility in Colon Cancer Cells.
65:1244-1250.
2005
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Correction.
64:8794-8794.
2004
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Alterations in Vascular Gene Expression in Invasive Breast Carcinoma.
64:7857-7866.
2004
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Haploid Inactivation of the Amplified-in-Breast Cancer 3 Coactivator Reduces the Inhibitory Effect of Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor on Cell Proliferation and Accelerates Polyoma Middle-T Antigen-Induced Mammary Tumorigenesis in Mice.
64:7169-7177.
2004
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The Phosphoprotein StarD10 Is Overexpressed in Breast Cancer and Cooperates with ErbB Receptors in Cellular Transformation.
64:3538-3544.
2004
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AIB1/SRC-3 Deficiency Affects Insulin-Like Growth Factor I Signaling Pathway and Suppresses -Ha- -induced Breast Cancer Initiation and Progression in Mice.
64:1875-1885.
2004
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Gene Expression Profiling-Based Prediction of Response of Colon Carcinoma Cells to 5-Fluorouracil and Camptothecin.
63:8791-8812.
2003
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TR3/Nur77 in colon cancer cell apoptosis.
63:5401-5407.
2003
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The direct mapping of the uptake of platinum anticancer agents in individual human ovarian adenocarcinoma cells using a hard x-ray microprobe.
63:1776-1779.
2003
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AACR special meeting in cancer research: colon cancer--genetics to prevention.
62:6779-6783.
2002
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A gene expression profile that defines colon cell maturation in vitro.
62:4791-4804.
2002
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Molecular basis for the synergistic interaction of Adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9).
61:8194-8202.
2001
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p21WAF1/cip1 is an important determinant of intestinal cell response to sulindac in vitro and in vivo.
61:6297-6302.
2001
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Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.
61:5349-5354.
2001
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Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.
61:5355-5361.
2001
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Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-GD3 ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts.
61:4474-4482.
2001
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Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation.
61:3465-3471.
2001
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Nitric oxide synthase II gene disruption: Implications for tumor growth and vascular endothelial growth factor production.
61:3182-3187.
2001
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Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function.
60:6818-6821.
2000
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Dissociation of staurosporine-induced apoptosis from G2-M arrest in SW620 human colonic carcinoma cells: Initiation of the apoptotic cascade is associated with elevation of the mitochondrial membrane potential (Δψ(m)).
60:6704-6713.
2000
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In vivo biodistribution of a humanized anti-Lewis Y monoclonal antibody (hu3s193) in MCF-7 xenografted BALB/c nude mice.
60:4804-4811.
2000
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Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.
60:4561-4572.
2000
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Construction, production, and characterization of humanized anti-Lewis Y monoclonal antibody 3S193 for targeted immunotherapy of solid tumors.
60:3254-3261.
2000
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Insights from Bcl-2 and Myc: Malignancy Involves Abrogation of Apoptosis as well as Sustained Proliferation.
59:1685S-1692S.
1999
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Methylation of the BRCA1 gene in sporadic breast cancer.
57:3347-3350.
1997
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Transformation of Astrocytes in Transgenic Mice Expressing SV40 T Antigen under the Transcriptional Control of the Glial Fibrillary Acidic Protein Promoter.
55:4302-4310.
1995
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Bioactivation of Aromatic Amines by Recombinant Human Cytochrome P4501A2 Expressed in Ames Tester Strain Bacteria: A Substitute for Activation by Mammalian Tissue Preparations.
55:799-802.
1995
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Inhibition of Angiogenesis by the Matrix Metalloprotease Inhibitor N-[2R-2-(Hydroxamidocarbonymethyl)-4-methylpentanoyl)-L-tryptophan Methylamide.
54:4715-4718.
1994
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Immunobead-PCR: A Technique for the Detection of Circulating Tumor Cells Using Immunomagnetic Beads and the Polymerase Chain Reaction.
53:3455-3458.
1993
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THERMOTOLERANCE IN THE ABSENCE OF INDUCED HEAT-SHOCK PROTEINS IN A MURINE LYMPHOMA.
52:2854-2861.
1992
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LOSS OF THE INTRINSIC HEAT-RESISTANCE OF HUMAN-CELLS AND CHANGES IN MR 70,000 HEAT-SHOCK PROTEIN EXPRESSION IN HUMAN X HAMSTER HYBRIDS.
51:2636-2641.
1991
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erba-related sequence coding for dna-binding hormone receptor localized to chromosome 3p21-3p25 and deleted in small cell lung carcinoma.
48:682-685.
1988
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Measurements of drinking patterns in the general population and possible applications in studies of the role of alcohol in cancer.
39:2830-2833.
1979
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MEASUREMENTS OF DRINKING PATTERNS IN THE GENERAL-POPULATION AND POSSIBLE APPLICATIONS IN STUDIES OF THE ROLE OF ALCOHOL IN CANCER.
39:2830-2833.
1979
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Abstract 2962: LRH-1 expression in breast cancer tissue and its association with phenotype and DNA methylation [Abstract]
2015
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Abstract 76: Liver receptor homologue-1 increases incidence of DMBA-induced mammary tumors
2014
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The HDAC inhibitory prodrug AN-7 reduces the toxicity of doxorubicin, anti-Her2 and radiation while augmenting their anticancer efficacy [Abstrat]
2011
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Cellular responses to doxorubicin-DNA adducts. Is cytotoxicity independent of p53 status?
2009
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BMP4 suppresses the progression of breast cancer through altered expression of metastasis regulating genes
2018
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Development of small-molecule mTORC1 radiotracers for evaluation of targeted therapy resistance using PET
2018
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Abstract 3932: Dual role of p120ctn in cancer: epithelial vs mesenchymal
2017
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Abstract 4266: Double somatic mutations as a cause of tumor mismatch repair-deficiency in population-based colorectal and endometrial cancer with Lynch-like syndrome
2017
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Abstract 5880: Acquired chemotherapeutic drug resistance in colorectal cancer is regulated by epithelial-to-mesenchymal transition and altered cellular pathways
2017
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Abstract 554: Checkpoint blockade therapy is improved by altering the immune suppressive microenvironment with IPI-549, a potent and selective inhibitor of PI3K-gamma, in preclinical models
2016
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The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
2016
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Abstract CT305: Phase I studies of a selective cMet inhibitor AZD6094 (HMPL504/volitinib) in patients with advanced solid tumors
2015
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Phase I safety and biodistribution study of 124I-PEG-AVP0458 diabody in patients with TAG-72 positive ovarian and prostate cancer
2015
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Excessive activation of the Src-kinase HCK in the tumor stroma promotes progression of solid tumors
2015
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Estrogen receptor alpha drives proliferation of prostate cancer through PI3K and MAPK signaling
2014
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Mobilization of tumor cells into the circulation during radiation therapy for lung cancer
2014
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Abstract P2-09-01: Targeting BCL-2 with the BH3 mimetic ABT-199 in ER-positive breast cancer
2013
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Excessive Wnt activity is insufficient for intestinal tumor growth or regeneration without gp130/Jak2/Stat3 signaling.
2013
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Defining the role of the cellular polarity regulator Scrib in epithelial tumorigenesis
2012
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Abstract 3108: Functional delineation of structural domains in Yorkie/Yes-associated protein
2010
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The Role of microRNA Genes in Breast Cancer Progression and Metastasis.
2009
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Contribution of specific Inhibitor of Apoptosis Proteins in distinct apoptotic pathways
2009
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The synergistic interaction of mitoxantrone and herceptin
2006
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AACR special meeting in cancer research: Colon cancer-genetics to prevention
2002
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Insights from bcl-2 and myc: Malignancy involves abrogation of apoptosis as well as sustained proliferation
1999
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The safety and pathological impact of neoadjuvant radiotherapy for local advanced breast cancer undergoing mastectomy and autologous reconstruction
2018
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