Circulation
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Overview
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High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy.
142:1448-1463.
2020
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Transcatheter aortic valve implantation represents an anti-inflammatory therapy via reduction of shear stress-induced, piezo-1-mediated monocyte activation.
142:1092-1105.
2020
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Deficiency of prebiotic fibre and insufficient signalling through gut metabolite sensing receptors leads to cardiovascular disease.
141:1393-1403.
2020
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Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction.
141:1080-1094.
2020
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Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation.
140:1170-1184.
2019
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Novel Role for the AnxA1-Fpr2/ALX signaling axis as a key regulator of platelet function to promote resolution of inflammation.
140:319-335.
2019
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Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration.
140:1834-1850.
2019
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Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes).
136:907-916.
2017
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Screening for Atrial Fibrillation A Report of the AF-SCREEN International Collaboration.
135:1851-1867.
2017
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Impact of Nurse-Led, Multidisciplinary Home-Based Intervention on Event-Free Survival Across the Spectrum of Chronic Heart Disease.
133:1867-1877.
2016
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Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.
129:2414-2425.
2014
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Dissociation of pentameric to monomeric C-Reactive protein localizes and aggravates inflammation.
130:35-50.
2014
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Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.
130:676-687.
2014
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NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis.
127:1888-1902.
2013
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Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis.
125:3117-3126.
2012
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Isolated Low Levels of High-Density Lipoprotein Cholesterol Are Associated With an Increased Risk of Coronary Heart Disease.
124:2056-2064.
2011
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Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension.
122:2529-2537.
2010
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Response to Letters Regarding Article, “Television Viewing Time and Mortality: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab)”.
122:E473-E473.
2010
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Continuous Glycoprotein-130–Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction.
122:145-155.
2010
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Television Viewing Time and Mortality.
121:384-391.
2010
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Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis.
118:258-267.
2008
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Risk of Cardiovascular and All-Cause Mortality in Individuals With Diabetes Mellitus, Impaired Fasting Glucose, and Impaired Glucose Tolerance.
116:151-157.
2007
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Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice.
115:2178-2187.
2007
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CD40 Ligand Mediates Inflammation Independently of CD40 by Interaction With Mac-1.
115:1571-1580.
2007
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Role of T Lymphocytes and Interferon-γ in Ischemic Stroke.
113:2105-2112.
2006
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CD40/CD40 Ligand Signaling in Mouse Cerebral Microvasculature After Focal Ischemia/Reperfusion.
111:1690-1696.
2005
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Reconstituted High-Density Lipoproteins Inhibit the Acute Pro-Oxidant and Proinflammatory Vascular Changes Induced by a Periarterial Collar in Normocholesterolemic Rabbits.
111:1543-1550.
2005
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Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand- Mimetic Properties.
105:E180-E180.
2002
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Relationship Between Lipid Levels and Clinical Outcomes in the Long-Term Intervention With Pravastatin in Ischemic Disease (LIPID) Trial.
105:1162-1169.
2002
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Heparin also interacts with selectins and modulates the cell adhesion process - Response.
102:E169-E169.
2000
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Flow Cytometric Monitoring of Glycoprotein IIb/IIIa Blockade and Platelet Function in Patients With Acute Myocardial Infarction Receiving Reteplase, Abciximab, and Ticlopidine.
102:1490-1496.
2000
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Evidence of Improving Prognosis in Heart Failure.
102:1126-1131.
2000
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Construction and Functional Evaluation of a Single-Chain Antibody Fusion Protein With Fibrin Targeting and Thrombin Inhibition After Activation by Factor Xa.
101:1158-1164.
2000
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Platelet Function During and After Thrombolytic Therapy for Acute Myocardial Infarction With Reteplase, Alteplase, or Streptokinase.
100:1858-1864.
1999
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Heparin Inhibits Ligand Binding to the Leukocyte Integrin Mac-1 (CD11b/CD18).
100:1533-1539.
1999
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Evidence That Macrophages in Atherosclerotic Lesions Contain Angiotensin II.
98:800-807.
1998
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Androgen Receptors Mediate Hypertrophy in Cardiac Myocytes.
98:256-261.
1998
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Inhaled Nitric Oxide Inhibits Human Platelet Aggregation, P-Selectin Expression, and Fibrinogen Binding In Vitro and In Vivo.
97:1481-1487.
1998
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Attenuation by Gemfibrozil of Expression of Plasminogen Activator Inhibitor Type 1 Induced by Insulin and its Precursors.
95:677-683.
1997
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Electronic cigarettes are effective for smoking cessation: evidence from a systematic review and meta-analysis
2014
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Eicosanoid Variation is Strongly Related to Blood Pressure in the General Population
2018
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Nlrp3 Inflammasome-Primed Neutrophils Amplify Granulopoiesis Following Myocardial Injury
2018
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Performance of ACC/AHA Cardiovascular Disease Risk Equations in Indigenous Australians With and Without Diabetes: The CRISP Study Collaboration
2018
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Therapeutic Inhibition of the Activated Leukocyte Integrin alphaMbeta2: A Novel Therapeutic Strategy in Treating Myocarditis in Mice
2018
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A Novel Class of Anti-inflammatory Binding Proteins Targeting alpha(M)ss(2): in vivo Inhibition of Activated Monocytes in Intravital Microscopy
2017
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Restoring Cardiac Function After Ischemia-Reperfusion Injury by Targeting Peripheral Blood Mononuclear Cells to Activated Platelets
2017
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The CD40L/Mac-1 Dyad Recruits Leukocytes During Cardiovascular Inflammation
2017
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Myeloperoxidase is a Potential Molecular Imaging and Therapeutic Target for the Identification and Stabilization of Unstable Atherosclerotic Plaque
2017
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Impact of a Multidisciplinary Management Program on Recurrent Hospitalization and Mortality in Older Individuals With Chronic Atrial Fibrillation: A Multicentre Randomized Trial
2014
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Global Changes in Cardiovascular Endurance of Children and Youth Since 1964: Systematic Analysis of 25 Million Fitness Test Results from 28 Countries
2013
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Increased Incidence of Cerebrovascular Events and Decreased Incidence of Coronary Events in Down Syndrome Individuals
2013
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Increased Risk of Ischemic Coronary and Cerebrovascular Events in Patients With Chronic Granulomatous Disease
2013
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M2 Macrophage Polarization is a Cause of Vascular Fibrosis and Stiffening in Hypertension
2013
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Relative Associations of Exercise Capacity With Ankle-Brachial Index vs Left Ventricular Function in Patients at Risk of Heart Failure: Preliminary Findings From the NIL-CHF Study
2013
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Relaxin Deficiency Impairs Endothelial Function and Volume Compliance in Mesenteric Arteries of Males
2013
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Abstract 10322: Molecular magnetic resonance imaging allows in vivo evaluation of ischemia-reperfusion injury by simultaneous targeting of activated platelets and myocardial necrosis in mice.
2013
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Molecular MRI of activated platelets using anti-libs-magnetoliposomes as a new strategy for timely detection of unstable plaques
2013
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A Chemokine C-C motif receptor 2 Antagonist, INCB3344, Reverses Hypertension and Macrophage Accumulation in the Artery Wall in Angiotensin II-Treated Mice
2012
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CD40 is Associated with Obesity in Humans and Stimulation of CD40 Signaling Limits Progression of Pre-Established Metabolic Disease in Mice
2012
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Dual Microbubble Targeting Improves in vitro Capture Efficiency of Ultrasound Micro-Bubbles Targeted to Selectins and Activated Platelets Although not Providing Additional Signal Effect for in vivo Imaging of Arterial Thrombosis
2012
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Genetic Absence of the Leukocyte Integrin Mac-1 Potentiates Adipose Tissue Inflammation by Enhancing Immune Cell Infiltration
2012
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Home-Based Management for Chronic Heart Failure Reduces Recurrent Hospital Stay and Total Healthcare Costs Compared to a Clinic-Based Program: Results from the WHICH? Trial
2012
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Impaired Intrinsic Exercise Capacity Predisposes to Progressive Left Ventricular Remodeling: Role of Mierovascular Endothelial Dysfunction and Impaired Glucose Utilization
2012
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Interruption of Classic CD4oL-CD4o Signaling But Not of the Novel CC4oL-Mac-1 Interaction Limits Arterial Neointima Formation in Mice
2012
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Nitric Oxide-Independent Stimulators of Soluble Guanylyl Cyclase Circumvent Platelet Nitric Oxide Resistance in Hypercholesterolemic Mice
2012
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Overcoming Persistent Hypertension in Primary Care: Potential Impact of a Proven Strategy of Intensive Blood Pressure Management Within a National Patient Cohort
2012
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Phage Display of Designed Ankyrin Repeat Proteins (DARPins) against the I Domain Of Mac-1 Results in Novel Diagnostic and Therapeutic Agents Specifically Acting on Activated Monocytes
2012
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Platelet-Targeted Microbubbles Allow Monitoring and Efficacy Testing of Thrombolytic Drugs in Molecular Ultrasound Imaging
2012
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Reversal of Vascular Macrophage Accumulation and Hypertension by a Chemokine C-C motif Receptor 2 Antagonist in Deoxycorticosteron/Salt-Treated Mice
2012
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The Soluble Guanylyl Cyclase (sGC) Activator BAY 58-2667 Selectively Limits Cardiomyocyte Hypertrophy - A Potential Therapeutic Advantage for Managing Left Ventricular Hypertrophy (LVH)
2012
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The Vasoprotective Actions of Nitroxyl, but not Nitric Oxide, are Maintained in Atherosclerotic Mice
2012
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Urine Proteome Analysis Allows Establishment of Polypeptide Patterns non-Invasively Reflecting Drug-Mediated Regression of Atherosclerosis in ApoE-/--Mice
2012
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Hypertensive heart failure in Nigerian Africans: insights from the Abeokuta heart failure registry
2012
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A Novel Antibody-Targeted Recombinant Plasminogen Activator Directed to Activated Platelets Allows Efficient Antithrombotic Prophylaxis
2011
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CD40 Deficiency Aggravates Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance in Mice
2011
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Clot-targeting Of CD39 Through Genetic Fusion To An Activated-platelet Specific Single-chain Antibody Provides Efficient Inhibition Of ADP Receptor-mediated Platelet Activation Without Systemic Platelet Inhibition
2011
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Genetic Deficiency of CD40L Attenuates Diet-Induced Adipose Tissue Inflammation - but Does Not Protect From Insulin Resistance and Hepatic Steatosis in Mice
2011
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Gradients in High-Density Lipoprotein Levels in Urban Africans Presenting with Communicable Versus Non-Communicable Forms of Heart Disease: The Heart of Soweto Study
2011
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Optimizing the Management of High Risk Patients with Atrial Fibrillation: Promising Signs From the Standard versus Atrial Fibrillation Specific ManagemenT Study (SAFETY)
2011
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The Pro-Atherogenic DNA-Binding Cytokine HMGB1 Binds to Activated Platelets via the Receptor for Advanced Glycation End Products (RAGE) and Toll-Like Receptor 2 (TLR 2)
2011
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A Platelet-specific Magnetic Resonance Imaging Contrast Agent Allows Detection of Thrombosis in a New Mouse Model of Coronary Artery Thrombosis
2010
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Bispecific Anti-GPIIb/IIIa Single Chain Antibodies for Stem Cell Homing
2010
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Calpain-10 Genetic Variants Interact with Plasma Saturated Fatty Acid Levels to Influence Insulin Resistance in Patients with Metabolic Syndrome
2010
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Coenzyme Q(10) Rescues Diastolic Dysfunction, Cardiomyocyte Hypertrophy and Cardiac Fibrosis in Female db/db Type 2 Diabetic Mice
2010
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Phosphoinositide 3-Kinase p110alpha (PI3Kalpha) Protects Against Diabetes-Induced Cardiac Superoxide Upregulation and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy
2010
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Radiographic Imaging of Specific Glycoprotein IIb/IIIa Receptor Binding Sites Allows the Detection of Activated Platelets in Arterial Thrombosis in Mice
2010
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A Proatherogenic Role for HMGB1 in Atherosclerosis
2009
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Absence of Female Protection in the Development of Progressive Cardiac Remodeling in db/db Type 2 Diabetic Mice
2009
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Cardiac-Specific IGF-1 Receptor (IGF-1R) Transgenic Mice Are Protected Against Cardiac Fibrosis and Diastolic Dysfunction in Type 1 Diabetic Cardiomyopathy
2009
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Dual Effects of Nox2-NADPH Oxidase During Atherosclerotic Plaque Development in Apolipoprotein E-Null Mice
2009
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Excessive Superoxide Production and Endothelial Dysfunction in Cerebral Arteries of Atherosclerotic Mice Are Due to Enhanced Activity of Nox2-containing NADPH-oxidase
2009
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Staphylococcal Superantigen-like 5 Induces Platelet Activation and Thrombosis via Binding to GPIb alpha and GPVI
2009
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A Magnetic Resonance Imaging Contrast Agent Targeted Towards Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis
2008
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Mechanisms of Cold-Induced Platelet Dysfunction: P2Y12 Receptor Blockade Protects Platelets during Hypothermia as Employed in Clinical Settings
2008
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Is being an immigrant a risk factor for CVD in Australia?
2008
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Design of activation-specific GPIlb/Illa inhibiting peptides
2007
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NADPH oxidase-dependent signaling involved in endothelial cell survival and proliferation: Role of Nox2 and Nox4
2007
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Simultaneous clot-largeted factor Xa inhibition and selective blockade of activated GPIlb/IIIa on platelets results in delayed but potent antithrombotic effects without bleeding time prolongation
2007
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Gender influences NADPH oxidase activity in the cerebral circulation
2006
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Generation of activation-specific human anti mac-1 (alpha M beta 2, CD 11b/CD18) single-chain antibodies as potential diagnostic tools and therapeutic agents
2006
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Ligand-binding induced epitopes on GPIIb/IIIa allow highly efficient clot-targeted anticoagulation without bleeding time prolongation: A biotechnological approach based on the single-chain antibody technology
2006
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A unique fusion protein combines clot targeting, platelet blockade and direct factor Xa inhibition in one molecule
2005
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Chronic treatment with the hexapeptide angiotensin IV improves endothelial dysfunction in apolipoprotein E-deficient mice
2005
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The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant Glut4-deficient mouse in vivo
2005
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Four-year follow-up of the multicenter Rct of coaching patients on achieving cardiovascular health (The COACH study) shows that the COACH program keeps patients out of hospital
2004
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Generation and affinity maturation of synthetic, conformation-specific single-chain antibodies against GPIIb/IIIa for a new therapeutic anti-platelet strategy
2003
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Sodium nitroprusside protects cardiomyocytes from simulated ischemia/reperfusion injury independently of cyclic GMP
2003
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The crucial role of the alpha-cytoplasmic tail for integrin alphaVbeta(3) dependent adhesion, cytoskeleton organisation and spreading under shear stress
2003
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Comparative cost-effectiveness of interventions for the primary prevention of coronary heart disease
2002
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Gene transfer of a fusion protein confers a specific functional blockade of vascular cell adhesion molecule-1 (VCAM-1; CD106) and results in a decreased recruitment of monocytes
2002
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Generation of human, activation-specific single chain antibodies directed against platelet integrin receptor GPIIb/IIIa
2002
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Inhibition of plasminogen activator inhibitor type-1 expression in human adipose tissue - A new pleiotropic effect of selected glitazones
2002
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Construction and functional evaluation of a new fibrin-targeted fibrinolytic: A recombinant fusion protein with an anti-fibrin single-chain antibody and a low molecular weight form single-chain urokinase
2001
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Effects of different thrombolytic treatment regimen with abciximab and tirofiban on platelet aggregation and platelet-leukocyte interaction
2001
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The GP IIb/IIIa blocker induced conformational change of GP IIb/IIIa demonstrates rapid reversibility that is inhibited in the presence of fibrinogen
2001
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Attenuation of PAI-1 synthesis by troglitazone in human arterial smooth muscle cells is affected by the 4g/5g polymorphism in the promoter of the PAI-1 gene
2000
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Abciximab binds to the leukocyte integrin Mac-1 (CD11b/CD18,alpha(M)beta(2)) and thereby results in a functional blockade in vitro and in vivo
1999
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Immobilized heparin mediates cell adhesion by its binding to the leukocyte integrin Mac-1
1999
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Direct monitoring of c7E3 and fibrinogen binding to platelets allows differentiation of GP IIb/IIIa blockade and ticlopidine effects on platelet function.
1998
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Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18) in vitro and in patients
1998
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Lipocortin-1 prevents depression of myocardial contractility in rat papillary muscle
1998
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Mechanical restitution predicts response to tachycardia in humans
1998
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Attenuation by gemfibrozil of PAI 1 expression induced by TGF-beta in human aortic smooth muscle cells
1997
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Differential regulation of insulin-induced expression of 2.2 kb and 3.2 kb PAI-1 mRNA by gemfibrozil
1997
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Distinct roles of ligand affinity and cytoskeletal anchorage in GP IIb/IIIa (alpha IIb beta 3)-mediated cell aggregation and adhesion
1997
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Induction of fibrinogen binding and platelet aggregation as an intrinsic property of various GP IIb/IIIa (allbb3) inhibitors
1997
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Platelet function during and after thrombolytic therapy for acute myocardial infarction with reteplase, alteplase, or streptokinase
1997
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The construction of a fusion protein for the inhibition of integrin mediated cell adhesion
1996
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A DELETION IN THE ALPHA-SUBUNIT LOCKS INTEGRIN ALPHA(IIB) BETA-3 IN A HIGH-AFFINITY STATE
1994
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A RECOMBINANT MOLECULE WITH HIGH-AFFINITY FOR FIBRIN EXHIBITS ANTITHROMBIN ACTIVITY AFTER CLEAVAGE BY FACTOR-XA
1994
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THROMBIN ACTIVITY DURING AND AFTER THROMBOLYSIS WITH RETEPLASE OR ALTEPLASE IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION
1994
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