Circulation

publication venue for

High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy. 142:1448-1463. 2020
Transcatheter aortic valve implantation represents an anti-inflammatory therapy via reduction of shear stress-induced, piezo-1-mediated monocyte activation. 142:1092-1105. 2020
Deficiency of prebiotic fibre and insufficient signalling through gut metabolite sensing receptors leads to cardiovascular disease. 141:1393-1403. 2020
Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction. 141:1080-1094. 2020
Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation. 140:1170-1184. 2019
Novel Role for the AnxA1-Fpr2/ALX signaling axis as a key regulator of platelet function to promote resolution of inflammation. 140:319-335. 2019
Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration. 140:1834-1850. 2019
Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes). 136:907-916. 2017
Screening for Atrial Fibrillation A Report of the AF-SCREEN International Collaboration. 135:1851-1867. 2017
Impact of Nurse-Led, Multidisciplinary Home-Based Intervention on Event-Free Survival Across the Spectrum of Chronic Heart Disease. 133:1867-1877. 2016
Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice. 129:2414-2425. 2014
Dissociation of pentameric to monomeric C-Reactive protein localizes and aggravates inflammation. 130:35-50. 2014
Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging. 130:676-687. 2014
NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis. 127:1888-1902. 2013
Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis. 125:3117-3126. 2012
Isolated Low Levels of High-Density Lipoprotein Cholesterol Are Associated With an Increased Risk of Coronary Heart Disease. 124:2056-2064. 2011
Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension. 122:2529-2537. 2010
Response to Letters Regarding Article, “Television Viewing Time and Mortality: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab)”. 122:E473-E473. 2010
Continuous Glycoprotein-130–Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction. 122:145-155. 2010
Television Viewing Time and Mortality. 121:384-391. 2010
Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis. 118:258-267. 2008
Risk of Cardiovascular and All-Cause Mortality in Individuals With Diabetes Mellitus, Impaired Fasting Glucose, and Impaired Glucose Tolerance. 116:151-157. 2007
Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice. 115:2178-2187. 2007
CD40 Ligand Mediates Inflammation Independently of CD40 by Interaction With Mac-1. 115:1571-1580. 2007
Role of T Lymphocytes and Interferon-γ in Ischemic Stroke. 113:2105-2112. 2006
CD40/CD40 Ligand Signaling in Mouse Cerebral Microvasculature After Focal Ischemia/Reperfusion. 111:1690-1696. 2005
Reconstituted High-Density Lipoproteins Inhibit the Acute Pro-Oxidant and Proinflammatory Vascular Changes Induced by a Periarterial Collar in Normocholesterolemic Rabbits. 111:1543-1550. 2005
Activating Effects of GPIIb/IIIa Blockers: An Intrinsic Consequence of Ligand- Mimetic Properties. 105:E180-E180. 2002
Relationship Between Lipid Levels and Clinical Outcomes in the Long-Term Intervention With Pravastatin in Ischemic Disease (LIPID) Trial. 105:1162-1169. 2002
Heparin also interacts with selectins and modulates the cell adhesion process - Response. 102:E169-E169. 2000
Flow Cytometric Monitoring of Glycoprotein IIb/IIIa Blockade and Platelet Function in Patients With Acute Myocardial Infarction Receiving Reteplase, Abciximab, and Ticlopidine. 102:1490-1496. 2000
Evidence of Improving Prognosis in Heart Failure. 102:1126-1131. 2000
Construction and Functional Evaluation of a Single-Chain Antibody Fusion Protein With Fibrin Targeting and Thrombin Inhibition After Activation by Factor Xa. 101:1158-1164. 2000
Platelet Function During and After Thrombolytic Therapy for Acute Myocardial Infarction With Reteplase, Alteplase, or Streptokinase. 100:1858-1864. 1999
Heparin Inhibits Ligand Binding to the Leukocyte Integrin Mac-1 (CD11b/CD18). 100:1533-1539. 1999
Evidence That Macrophages in Atherosclerotic Lesions Contain Angiotensin II. 98:800-807. 1998
Androgen Receptors Mediate Hypertrophy in Cardiac Myocytes. 98:256-261. 1998
Inhaled Nitric Oxide Inhibits Human Platelet Aggregation, P-Selectin Expression, and Fibrinogen Binding In Vitro and In Vivo. 97:1481-1487. 1998
Attenuation by Gemfibrozil of Expression of Plasminogen Activator Inhibitor Type 1 Induced by Insulin and its Precursors. 95:677-683. 1997
Electronic cigarettes are effective for smoking cessation: evidence from a systematic review and meta-analysis 2014
Eicosanoid Variation is Strongly Related to Blood Pressure in the General Population 2018
Nlrp3 Inflammasome-Primed Neutrophils Amplify Granulopoiesis Following Myocardial Injury 2018
Performance of ACC/AHA Cardiovascular Disease Risk Equations in Indigenous Australians With and Without Diabetes: The CRISP Study Collaboration 2018
Therapeutic Inhibition of the Activated Leukocyte Integrin alphaMbeta2: A Novel Therapeutic Strategy in Treating Myocarditis in Mice 2018
A Novel Class of Anti-inflammatory Binding Proteins Targeting alpha(M)ss(2): in vivo Inhibition of Activated Monocytes in Intravital Microscopy 2017
Restoring Cardiac Function After Ischemia-Reperfusion Injury by Targeting Peripheral Blood Mononuclear Cells to Activated Platelets 2017
The CD40L/Mac-1 Dyad Recruits Leukocytes During Cardiovascular Inflammation 2017
Myeloperoxidase is a Potential Molecular Imaging and Therapeutic Target for the Identification and Stabilization of Unstable Atherosclerotic Plaque 2017
Impact of a Multidisciplinary Management Program on Recurrent Hospitalization and Mortality in Older Individuals With Chronic Atrial Fibrillation: A Multicentre Randomized Trial 2014
Global Changes in Cardiovascular Endurance of Children and Youth Since 1964: Systematic Analysis of 25 Million Fitness Test Results from 28 Countries 2013
Increased Incidence of Cerebrovascular Events and Decreased Incidence of Coronary Events in Down Syndrome Individuals 2013
Increased Risk of Ischemic Coronary and Cerebrovascular Events in Patients With Chronic Granulomatous Disease 2013
M2 Macrophage Polarization is a Cause of Vascular Fibrosis and Stiffening in Hypertension 2013
Relative Associations of Exercise Capacity With Ankle-Brachial Index vs Left Ventricular Function in Patients at Risk of Heart Failure: Preliminary Findings From the NIL-CHF Study 2013
Relaxin Deficiency Impairs Endothelial Function and Volume Compliance in Mesenteric Arteries of Males 2013
Abstract 10322: Molecular magnetic resonance imaging allows in vivo evaluation of ischemia-reperfusion injury by simultaneous targeting of activated platelets and myocardial necrosis in mice. 2013
Molecular MRI of activated platelets using anti-libs-magnetoliposomes as a new strategy for timely detection of unstable plaques 2013
A Chemokine C-C motif receptor 2 Antagonist, INCB3344, Reverses Hypertension and Macrophage Accumulation in the Artery Wall in Angiotensin II-Treated Mice 2012
CD40 is Associated with Obesity in Humans and Stimulation of CD40 Signaling Limits Progression of Pre-Established Metabolic Disease in Mice 2012
Dual Microbubble Targeting Improves in vitro Capture Efficiency of Ultrasound Micro-Bubbles Targeted to Selectins and Activated Platelets Although not Providing Additional Signal Effect for in vivo Imaging of Arterial Thrombosis 2012
Genetic Absence of the Leukocyte Integrin Mac-1 Potentiates Adipose Tissue Inflammation by Enhancing Immune Cell Infiltration 2012
Home-Based Management for Chronic Heart Failure Reduces Recurrent Hospital Stay and Total Healthcare Costs Compared to a Clinic-Based Program: Results from the WHICH? Trial 2012
Impaired Intrinsic Exercise Capacity Predisposes to Progressive Left Ventricular Remodeling: Role of Mierovascular Endothelial Dysfunction and Impaired Glucose Utilization 2012
Interruption of Classic CD4oL-CD4o Signaling But Not of the Novel CC4oL-Mac-1 Interaction Limits Arterial Neointima Formation in Mice 2012
Nitric Oxide-Independent Stimulators of Soluble Guanylyl Cyclase Circumvent Platelet Nitric Oxide Resistance in Hypercholesterolemic Mice 2012
Overcoming Persistent Hypertension in Primary Care: Potential Impact of a Proven Strategy of Intensive Blood Pressure Management Within a National Patient Cohort 2012
Phage Display of Designed Ankyrin Repeat Proteins (DARPins) against the I Domain Of Mac-1 Results in Novel Diagnostic and Therapeutic Agents Specifically Acting on Activated Monocytes 2012
Platelet-Targeted Microbubbles Allow Monitoring and Efficacy Testing of Thrombolytic Drugs in Molecular Ultrasound Imaging 2012
Reversal of Vascular Macrophage Accumulation and Hypertension by a Chemokine C-C motif Receptor 2 Antagonist in Deoxycorticosteron/Salt-Treated Mice 2012
The Soluble Guanylyl Cyclase (sGC) Activator BAY 58-2667 Selectively Limits Cardiomyocyte Hypertrophy - A Potential Therapeutic Advantage for Managing Left Ventricular Hypertrophy (LVH) 2012
The Vasoprotective Actions of Nitroxyl, but not Nitric Oxide, are Maintained in Atherosclerotic Mice 2012
Urine Proteome Analysis Allows Establishment of Polypeptide Patterns non-Invasively Reflecting Drug-Mediated Regression of Atherosclerosis in ApoE-/--Mice 2012
Hypertensive heart failure in Nigerian Africans: insights from the Abeokuta heart failure registry 2012
A Novel Antibody-Targeted Recombinant Plasminogen Activator Directed to Activated Platelets Allows Efficient Antithrombotic Prophylaxis 2011
CD40 Deficiency Aggravates Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance in Mice 2011
Clot-targeting Of CD39 Through Genetic Fusion To An Activated-platelet Specific Single-chain Antibody Provides Efficient Inhibition Of ADP Receptor-mediated Platelet Activation Without Systemic Platelet Inhibition 2011
Genetic Deficiency of CD40L Attenuates Diet-Induced Adipose Tissue Inflammation - but Does Not Protect From Insulin Resistance and Hepatic Steatosis in Mice 2011
Gradients in High-Density Lipoprotein Levels in Urban Africans Presenting with Communicable Versus Non-Communicable Forms of Heart Disease: The Heart of Soweto Study 2011
Optimizing the Management of High Risk Patients with Atrial Fibrillation: Promising Signs From the Standard versus Atrial Fibrillation Specific ManagemenT Study (SAFETY) 2011
The Pro-Atherogenic DNA-Binding Cytokine HMGB1 Binds to Activated Platelets via the Receptor for Advanced Glycation End Products (RAGE) and Toll-Like Receptor 2 (TLR 2) 2011
A Platelet-specific Magnetic Resonance Imaging Contrast Agent Allows Detection of Thrombosis in a New Mouse Model of Coronary Artery Thrombosis 2010
Bispecific Anti-GPIIb/IIIa Single Chain Antibodies for Stem Cell Homing 2010
Calpain-10 Genetic Variants Interact with Plasma Saturated Fatty Acid Levels to Influence Insulin Resistance in Patients with Metabolic Syndrome 2010
Coenzyme Q(10) Rescues Diastolic Dysfunction, Cardiomyocyte Hypertrophy and Cardiac Fibrosis in Female db/db Type 2 Diabetic Mice 2010
Phosphoinositide 3-Kinase p110alpha (PI3Kalpha) Protects Against Diabetes-Induced Cardiac Superoxide Upregulation and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy 2010
Radiographic Imaging of Specific Glycoprotein IIb/IIIa Receptor Binding Sites Allows the Detection of Activated Platelets in Arterial Thrombosis in Mice 2010
A Proatherogenic Role for HMGB1 in Atherosclerosis 2009
Absence of Female Protection in the Development of Progressive Cardiac Remodeling in db/db Type 2 Diabetic Mice 2009
Cardiac-Specific IGF-1 Receptor (IGF-1R) Transgenic Mice Are Protected Against Cardiac Fibrosis and Diastolic Dysfunction in Type 1 Diabetic Cardiomyopathy 2009
Dual Effects of Nox2-NADPH Oxidase During Atherosclerotic Plaque Development in Apolipoprotein E-Null Mice 2009
Excessive Superoxide Production and Endothelial Dysfunction in Cerebral Arteries of Atherosclerotic Mice Are Due to Enhanced Activity of Nox2-containing NADPH-oxidase 2009
Staphylococcal Superantigen-like 5 Induces Platelet Activation and Thrombosis via Binding to GPIb alpha and GPVI 2009
A Magnetic Resonance Imaging Contrast Agent Targeted Towards Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis 2008
Mechanisms of Cold-Induced Platelet Dysfunction: P2Y12 Receptor Blockade Protects Platelets during Hypothermia as Employed in Clinical Settings 2008
Is being an immigrant a risk factor for CVD in Australia? 2008
Design of activation-specific GPIlb/Illa inhibiting peptides 2007
NADPH oxidase-dependent signaling involved in endothelial cell survival and proliferation: Role of Nox2 and Nox4 2007
Simultaneous clot-largeted factor Xa inhibition and selective blockade of activated GPIlb/IIIa on platelets results in delayed but potent antithrombotic effects without bleeding time prolongation 2007
Gender influences NADPH oxidase activity in the cerebral circulation 2006
Generation of activation-specific human anti mac-1 (alpha M beta 2, CD 11b/CD18) single-chain antibodies as potential diagnostic tools and therapeutic agents 2006
Ligand-binding induced epitopes on GPIIb/IIIa allow highly efficient clot-targeted anticoagulation without bleeding time prolongation: A biotechnological approach based on the single-chain antibody technology 2006
A unique fusion protein combines clot targeting, platelet blockade and direct factor Xa inhibition in one molecule 2005
Chronic treatment with the hexapeptide angiotensin IV improves endothelial dysfunction in apolipoprotein E-deficient mice 2005
The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant Glut4-deficient mouse in vivo 2005
Four-year follow-up of the multicenter Rct of coaching patients on achieving cardiovascular health (The COACH study) shows that the COACH program keeps patients out of hospital 2004
Generation and affinity maturation of synthetic, conformation-specific single-chain antibodies against GPIIb/IIIa for a new therapeutic anti-platelet strategy 2003
Sodium nitroprusside protects cardiomyocytes from simulated ischemia/reperfusion injury independently of cyclic GMP 2003
The crucial role of the alpha-cytoplasmic tail for integrin alphaVbeta(3) dependent adhesion, cytoskeleton organisation and spreading under shear stress 2003
Comparative cost-effectiveness of interventions for the primary prevention of coronary heart disease 2002
Gene transfer of a fusion protein confers a specific functional blockade of vascular cell adhesion molecule-1 (VCAM-1; CD106) and results in a decreased recruitment of monocytes 2002
Generation of human, activation-specific single chain antibodies directed against platelet integrin receptor GPIIb/IIIa 2002
Inhibition of plasminogen activator inhibitor type-1 expression in human adipose tissue - A new pleiotropic effect of selected glitazones 2002
Construction and functional evaluation of a new fibrin-targeted fibrinolytic: A recombinant fusion protein with an anti-fibrin single-chain antibody and a low molecular weight form single-chain urokinase 2001
Effects of different thrombolytic treatment regimen with abciximab and tirofiban on platelet aggregation and platelet-leukocyte interaction 2001
The GP IIb/IIIa blocker induced conformational change of GP IIb/IIIa demonstrates rapid reversibility that is inhibited in the presence of fibrinogen 2001
Attenuation of PAI-1 synthesis by troglitazone in human arterial smooth muscle cells is affected by the 4g/5g polymorphism in the promoter of the PAI-1 gene 2000
Abciximab binds to the leukocyte integrin Mac-1 (CD11b/CD18,alpha(M)beta(2)) and thereby results in a functional blockade in vitro and in vivo 1999
Immobilized heparin mediates cell adhesion by its binding to the leukocyte integrin Mac-1 1999
Direct monitoring of c7E3 and fibrinogen binding to platelets allows differentiation of GP IIb/IIIa blockade and ticlopidine effects on platelet function. 1998
Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18) in vitro and in patients 1998
Lipocortin-1 prevents depression of myocardial contractility in rat papillary muscle 1998
Mechanical restitution predicts response to tachycardia in humans 1998
Attenuation by gemfibrozil of PAI 1 expression induced by TGF-beta in human aortic smooth muscle cells 1997
Differential regulation of insulin-induced expression of 2.2 kb and 3.2 kb PAI-1 mRNA by gemfibrozil 1997
Distinct roles of ligand affinity and cytoskeletal anchorage in GP IIb/IIIa (alpha IIb beta 3)-mediated cell aggregation and adhesion 1997
Induction of fibrinogen binding and platelet aggregation as an intrinsic property of various GP IIb/IIIa (allbb3) inhibitors 1997
Platelet function during and after thrombolytic therapy for acute myocardial infarction with reteplase, alteplase, or streptokinase 1997
The construction of a fusion protein for the inhibition of integrin mediated cell adhesion 1996
A DELETION IN THE ALPHA-SUBUNIT LOCKS INTEGRIN ALPHA(IIB) BETA-3 IN A HIGH-AFFINITY STATE 1994
A RECOMBINANT MOLECULE WITH HIGH-AFFINITY FOR FIBRIN EXHIBITS ANTITHROMBIN ACTIVITY AFTER CLEAVAGE BY FACTOR-XA 1994
THROMBIN ACTIVITY DURING AND AFTER THROMBOLYSIS WITH RETEPLASE OR ALTEPLASE IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION 1994

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Cardiovascular System & Hematology (Science Metrix)

La Trobe University Scholars

Circulation Journal

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