Journal of Biological Chemistry
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Overview
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"Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution.
295:3080-3098.
2020
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Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency.
294:794-804.
2019
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The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance.
294:15876-15888.
2019
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The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal Vitamin A homeostasis, but is required for exogenous atRA clearance.
294.
2019
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The role of lipids in α-synuclein misfolding and neurotoxicity.
294:9016-9028.
2019
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Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins.
293:6593-6602.
2018
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Defining the distinct, intrinsic properties of the novel type I
interferon, IFNϵ.
293:3168-3179.
2018
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Drosophila melanogaster Guk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.
293:4519-4531.
2018
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Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
293:5464-5477.
2018
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Multi-tiered pairing selectivity between E2 ubiquitin–conjugating enzymes and E3 ligases.
293:16324-16336.
2018
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Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order and molecular chaperone activity.
293:89-99.
2018
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Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.
293:69-88.
2018
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Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
293:16559-16571.
2018
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A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors.
292:21149-21158.
2017
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PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome.
292:826-836.
2017
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Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor β-PIX.
292:20425-20436.
2017
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Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
292:9010-9021.
2017
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Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase.
292:20461-20471.
2017
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Structure–function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins.
292:15143-15158.
2017
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Dimerization of Bacterial Diaminopimelate Decarboxylase Is Essential for Catalysis.
291:9785-9795.
2016
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Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
291:25375-25386.
2016
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Exosomes in the pathology of neurodegenerative diseases.
291:26589-26597.
2016
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Extending Halogen-based Medicinal Chemistry to Proteins IODO-INSULIN AS A CASE STUDY.
291:27023-27041+.
2016
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Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner.
291:12445-12466.
2016
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Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor.
291:15473-15481.
2016
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Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions.
291:5128-5137.
2016
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Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism.
291:1866-1876.
2016
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The N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation.
291:14600-14608.
2016
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i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.
291:12641-12657+.
2016
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Cytosolic PTEN-induced putative kinase 1 is stabilized by the NF-κB pathway and promotes non-selective mitophagy.
290:16882-16893.
2015
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Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion Syndrome.
290:23240-23253.
2015
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Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.
290:7141-7150.
2015
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The Structure of the Atypical Killer Cell Immunoglobulin-like Receptor, KIR2DL4.
290:10460-10471.
2015
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The interferon-induced transmembrane proteins, IFITM1, IFITM2, and IFITM3 inhibit hepatitis C virus entry.
290:25946-25959.
2015
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The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes.
290:3455-3467.
2015
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The Intestinal Epithelial Cell Differentiation Marker Intestinal Alkaline Phosphatase (ALPi) Is Selectively Induced by Histone Deacetylase Inhibitors (HDACi) in Colon Cancer Cells in a Kruppel-like Factor 5 (KLF5)-dependent Manner.
289:25306-25316.
2014
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Structure of theAcinetobacter baumanniiDithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction Site.
289:19869-19880.
2014
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Aromatic Anchor at an Invariant Hormone-Receptor Interface FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN.
289:34709-34727.
2014
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Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells.
289:19758-19768.
2014
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Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell.
289:6669-6680.
2014
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Prion infection impairs cholesterol metabolism in neuronal cells.
289:789-802.
2014
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Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.
289:31077-31087.
2014
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The Merozoite Surface Protein 1 Complex Is a Platform for Binding to Human Erythrocytes by Plasmodium falciparum.
289:25655-25669.
2014
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The functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains.
289:36001-36017.
2014
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Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor.
288:36141-36148.
2013
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Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein.
288:31115-31126.
2013
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Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission.
288:27584-27593.
2013
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High-affinity Cyclic Peptide Matriptase Inhibitors.
288:13885-13896.
2013
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Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis.
288:9238-9248.
2013
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Comparison of orientation and rotational motion of skeletal muscle cross-bridges containing phosphorylated and dephosphorylated myosin regulatory light chain.
288:7012-7023.
2013
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Intracellular Trafficking of the KV1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease.
288:6451-6464.
2013
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Cyclin-dependent Kinase E1 (CDKE1) Provides a Cellular Switch in Plants between Growth and Stress Responses.
288:3449-3459.
2013
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A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4.
288:15821-15829.
2013
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A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity.
288:9696-9709.
2013
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Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15.
288:37267-37276.
2013
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Enhanced asynchronous Ca2⁺ oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion.
288:13831-13841.
2013
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Molecular Determinants of the Substrate Specificity of the Complement-initiating Protease, C1r.
288:15571-15580.
2013
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Structural basis of subtilase cytotoxin SubAB assembly..
288:27505-27516.
2013
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Subcomplexes of ancestral respiratory complex i subunits rapidly turn over in vivo as productive assembly intermediates in arabidopsis.
288:5707-5717.
2013
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The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome.
288:22399-22407.
2013
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Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion.
288:1907-1917.
2013
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LETM Proteins Play a Role in the Accumulation of Mitochondrially Encoded Proteins inArabidopsis thalianaandAtLETM2Displays Parent of Origin Effects.
287:41757-41773.
2012
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A 22-mer Segment in the Structurally Pliable Regulatory Domain of Metazoan CTP: Phosphocholine Cytidylyltransferase Facilitates Both Silencing and Activating Functions.
287:38980-38991.
2012
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The Retinoblastoma Protein Selectively Represses E2F1 Targets via a TAAC DNA Element during Cellular Senescence.
287:37540-37551.
2012
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Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 fromPlasmodium falciparum.
287:32922-32939.
2012
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Insights into Processing and Cyclization Events Associated with Biosynthesis of the Cyclic Peptide Kalata B1.
287:28037-28046.
2012
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Accumulation of Newly Synthesized F1in VivoinArabidopsisMitochondria Provides Evidence for Modular Assembly of the Plant F1FoATP Synthase.
287:25749-25757.
2012
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TGD1, -2, and -3 Proteins Involved in Lipid Trafficking Form ATP-binding Cassette (ABC) Transporter with Multiple Substrate-binding Proteins.
287:21406-21415.
2012
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Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity.
287:19961-19972.
2012
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A Helical Conotoxin fromConus imperialisHas a Novel Cysteine Framework and Defines a New Superfamily.
287:14973-14983.
2012
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Transcription Factor GATA4 Is Activated but Not Required for Insulin-like Growth Factor 1 (IGF1)-induced Cardiac Hypertrophy.
287:9827-9834.
2012
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Selective inhibition of Biotin Protein Ligase from Staphylococcus aureus.
287:17823-17832.
2012
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The prion protein preference of sporadic Creutzfeldt-Jakob disease subtypes.
287:36465-36472.
2012
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Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure.
286:30837-30846.
2011
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Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription.
286:26406-26417.
2011
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Separation of Fast from Slow Anabolism by Site-specific PEGylation of Insulin-like Growth Factor I (IGF-I).
286:19501-19510.
2011
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Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization.
286:17015-17028.
2011
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TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4.
286:13805-13814.
2011
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In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8.
286:13282-13291.
2011
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Opposing Actions of Extracellular Signal-regulated Kinase (ERK) and Signal Transducer and Activator of Transcription 3 (STAT3) in Regulating Microtubule Stabilization during Cardiac Hypertrophy.
286:1576-1587.
2011
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Insights into structure and function of the active site of SoxAX cytochromes.
286:24872-24881.
2011
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Mutation to bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis.
286:7123-7131.
2011
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S1 Pocket of a Bacterially Derived Subtilisin-like Protease Underpins Effective Tissue Destruction.
286:42180-42187.
2011
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The phytosulfokine (PSK) receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants.
286:22580-22588.
2011
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Permeabilization of Fungal Hyphae by the Plant Defensin NaD1 Occurs through a Cell Wall-dependent Process.
285:37513-37520.
2010
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Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor.
285:36876-36883.
2010
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Conserved and Novel Functions forArabidopsis thalianaMIA40 in Assembly of Proteins in Mitochondria and Peroxisomes.
285:36138-36148.
2010
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Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain.
285:32282-32292.
2010
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Tetrahydrolipstatin Inhibition, Functional Analyses, and Three-dimensional Structure of a Lipase Essential for Mycobacterial Viability.
285:30050-30060.
2010
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Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool.
285:21807-21816.
2010
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Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity.
285:20213-20223.
2010
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Structural and Functional Characterization of Three DsbA Paralogues fromSalmonella entericaSerovar Typhimurium.
285:18423-18432.
2010
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Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding.
285:17525-17536.
2010
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Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites.
285:14815-14822.
2010
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Potassium-activated GTPase Reaction in the G Protein-coupled Ferrous Iron Transporter B.
285:14594-14602.
2010
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Nerve Growth Factor Inhibits Metalloproteinase-Disintegrins and Blocks Ectodomain Shedding of Platelet Glycoprotein VI.
285:11793-11799.
2010
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Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
285:5188-5195.
2010
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Vaccinia Virus F1L Interacts with Bak Using Highly Divergent Bcl-2 Homology Domains and Replaces the Function of Mcl-1.
285:4695-4708.
2010
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Role of Plasmodium berghei cGMP-dependent Protein Kinase in Late Liver Stage Development.
285:3282-3288.
2010
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TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis.
284:35906-35915.
2009
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Characterization of a Serine Protease Homologous to House Dust Mite Group 3 Allergens from the Scabies MiteSarcoptes scabiei.
284:34413-34422.
2009
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Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis.
284:33224-33232.
2009
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Biochemical Characterization of Two Wheat PhosphoethanolamineN-Methyltransferase Isoforms with Different Sensitivities to Inhibition by Phosphatidic Acid.
284:31962-31971.
2009
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Novel Bcl-2 Homology-3 Domain-like Sequences Identified from Screening Randomized Peptide Libraries for Inhibitors of the Pro-survival Bcl-2 Proteins.
284:31315-31326.
2009
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Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands.
284:30508-30517.
2009
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EKLF/KLF1 Controls Cell Cycle Entry via Direct Regulation of E2f2.
284:20966-20974.
2009
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The Homocysteine-inducible Endoplasmic Reticulum Stress Protein Counteracts Calcium Store Depletion and Induction of CCAAT Enhancer-binding Protein Homologous Protein in a Neurotoxin Model of Parkinson Disease.
284:18323-18333.
2009
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The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes.
284:17835-17845.
2009
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Properties of the Thioredoxin Fold Superfamily Are Modulated by a Single Amino Acid Residue.
284:10150-10159.
2009
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Rapid Optimization of a Peptide Inhibitor of Malaria Parasite Invasion by ComprehensiveN-Methyl Scanning.
284:9361-9371.
2009
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Endogenous Calpain-3 Activation Is Primarily Governed by Small Increases in Resting Cytoplasmic [Ca2+] and Is Not Dependent on Stretch.
284:7811-7819.
2009
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Regulation of Prion Gene Expression by Transcription Factors SP1 and Metal Transcription Factor-1.
284:1291-1301.
2009
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Nedd4 Family-interacting Protein 1 (Ndfip1) Is Required for the Exosomal Secretion of Nedd4 Family Proteins.
283:32621-32627.
2008
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Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 fromNeisseria meningitidis.
283:32452-32461.
2008
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Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment.
283:31633-31640.
2008
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Crystal Structure of a UDP-glucose-specific Glycosyltransferase from a Mycobacterium Species.
283:27881-27890.
2008
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Structure and Evolution of a Novel Dimeric Enzyme from a Clinically Important Bacterial Pathogen.
283:27598-27603.
2008
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Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function.
283:19499-19510.
2008
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The Plant Defensin, NaD1, Enters the Cytoplasm of Fusarium Oxysporum Hyphae.
283:14445-14452.
2008
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Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase fromLegionella pneumophila.
283:12909-12918.
2008
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Molecular Dissection of gp130-dependent Pathways in Hepatocytes during Liver Regeneration.
283:9886-9895.
2008
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Selective Intracellular Release of Copper and Zinc Ions from Bis(thiosemicarbazonato) Complexes Reduces Levels of Alzheimer Disease Amyloid-β Peptide.
283:4568-4577.
2008
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Cell Surface-expressed Cation-independent Mannose 6-Phosphate Receptor (CD222) Binds Enzymatically Active Heparanase Independently of Mannose 6-Phosphate to Promote Extracellular Matrix Degradation.
283:4165-4176.
2008
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Staphylococcus aureus DsbA Does Not Have a Destabilizing Disulfide.
283:4261-4271.
2008
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The D-Diastereomer of ShK Toxin Selectively Blocks Voltage-gated K+Channels and Inhibits T Lymphocyte Proliferation.
283:988-997.
2008
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Distinguishing Aggrecan Loss from Aggrecan Proteolysis in ADAMTS-4 and ADAMTS-5 Single and Double Deficient Mice.
282:37420-37428.
2007
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The Cytotoxic Lipid Peroxidation Product 4-Hydroxy-2-nonenal Covalently Modifies a Selective Range of Proteins Linked to Respiratory Function in Plant Mitochondria.
282:37436-37447.
2007
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DNA Accelerates the Inhibition of Human Cathepsin V by Serpins.
282:36980-36986.
2007
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Structural Basis for the Recognition and Cross-linking of Amyloid Fibrils by Human Apolipoprotein E.
282:35831-35841.
2007
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Structure/Function Characterization of μ-Conotoxin KIIIA, an Analgesic, Nearly Irreversible Blocker of Mammalian Neuronal Sodium Channels.
282:30699-30706.
2007
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An Asparaginyl Endopeptidase Mediatesin VivoProtein Backbone Cyclization.
282:29721-29728.
2007
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Differential Gene Expression and Subcellular Targeting of Arabidopsis GlutathioneS-Transferase F8 Is Achieved through Alternative Transcription Start Sites.
282:28915-28928.
2007
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A Novel Plant Protein-disulfide Isomerase Involved in the Oxidative Folding of Cystine Knot Defense Proteins.
282:20435-20446.
2007
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Oxygen Initiation of Respiration and Mitochondrial Biogenesis in Rice.
282:15619-15631.
2007
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Novel Mechanism of Activation of NADPH Oxidase 5.
282:6494-6507.
2007
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Ankyrin Repeat and Suppressors of Cytokine Signaling Box Protein Asb-9 Targets Creatine Kinase B for Degradation.
282:4728-4737.
2007
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Role of ABCG1 and ABCA1 in Regulation of Neuronal Cholesterol Efflux to Apolipoprotein E Discs and Suppression of Amyloid-β Peptide Generation.
282:2851-2861.
2007
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The Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor AG1478 Increases the Formation of Inactive Untethered EGFR Dimers.
282:2840-2850.
2007
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Induction of the Unfolded Protein Response in Familial Amyotrophic Lateral Sclerosis and Association of Protein-disulfide Isomerase with Superoxide Dismutase 1.
281:30152-30165.
2006
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Molecular Analysis of the Interaction between the Hematopoietic Master Transcription Factors GATA-1 and PU.1.
281:28296-28306.
2006
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Tracking the Unfolding Pathway of a Multirepeat Protein via Tryptophan Scanning.
281:24345-24350.
2006
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The Wnt Co-receptor LRP5 Is Essential for Skeletal Mechanotransduction but Not for the Anabolic Bone Response to Parathyroid Hormone Treatment.
281:23698-23711.
2006
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Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-dependent Up-regulation of Metalloprotease Activity.
281:17670-17680.
2006
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Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer.
281:13548-13558.
2006
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The Comparative Roles of Suppressor of Cytokine Signaling-1 and -3 in the Inhibition and Desensitization of Cytokine Signaling.
281:11135-11143.
2006
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Differences in eNOS Activity Because of Subcellular Localization Are Dictated by Phosphorylation State Rather than the Local Calcium Environment.
281:1477-1488.
2006
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The Murine Orthologue of Human Antichymotrypsin.
280:43168-43178.
2005
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Elucidation of the Substrate Specificity of the C1s Protease of the Classical Complement Pathway.
280:39510-39514.
2005
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Src Kinase Activates Endothelial Nitric-oxide Synthase by Phosphorylating Tyr-83.
280:35943-35952.
2005
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Early Growth Response Gene 1 (EGR1) Regulates Heparanase Gene Transcription in Tumor Cells.
280:35136-35147.
2005
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Histidine-rich Glycoprotein Specifically Binds to Necrotic Cells via Its Amino-terminal Domain and Facilitates Necrotic Cell Phagocytosis.
280:35733-35741.
2005
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High Resolution Structures of Highly Bulged Viral Epitopes Bound to Major Histocompatibility Complex Class I.
280:23900-23909.
2005
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The High Resolution Crystal Structure of the Human Tumor Suppressor Maspin Reveals a Novel Conformational Switch in the G-helix.
280:22356-22364.
2005
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The X-ray Structure of a Hemipteran Ecdysone Receptor Ligand-binding Domain.
280:22258-22269.
2005
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The C-terminal Region of TIM17 Links the Outer and Inner Mitochondrial Membranes inArabidopsisand Is Essential for Protein Import.
280:16476-16483.
2005
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Dissection of the Mitochondrial Import and Assembly Pathway for Human Tom40.
280:11535-11543.
2005
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Calcium-dependent Open/Closed Conformations and Interfacial Energy Maps of Reconstituted Hemichannels.
280:10646-10654.
2005
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Hsp72 Inhibits Fas-mediated Apoptosis Upstream of the Mitochondria in Type II Cells.
280:9005-9012.
2005
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The Carboxyl-terminal Third of the Dicarboxylate Carrier Is Crucial for Productive Association with the Inner Membrane Twin-pore Translocase.
280:6215-6221.
2005
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Hsp72 Inhibits Apoptosis Upstream of the Mitochondria and Not through Interactions with Apaf-1.
279:51490-51499.
2004
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A Biophysical Analysis of the Tetratricopeptide Repeat-rich Mitochondrial Import Receptor, Tom70, Reveals an Elongated Monomer That Is Inherently Flexible, Unstable, and Unfolds via a Multistate Pathway.
279:46448-46454.
2004
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Conserved Structural and Sequence Elements Implicated in the Processing of Gene-encoded Circular Proteins.
279:46858-46867.
2004
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Post-translational Modifications of Arabinogalactan-peptides ofArabidopsis thaliana.
279:45503-45511.
2004
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Mammary Gland Remodeling Depends on gp130 Signaling through Stat3 and MAPK.
279:44093-44100.
2004
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Detection and Mapping of Widespread Intermolecular Protein Disulfide Formation during Cardiac Oxidative Stress Using Proteomics with Diagonal Electrophoresis.
279:41352-41360.
2004
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Erratum: Stereochemistry of β-, γ-, and ε-ring formation in bacterial C50 carotenoids (Journal of Biological Chemistry (1981) 256 (11607-11611).
279:39186.
2004
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Plasminogen Is Tethered with High Affinity to the Cell Surface by the Plasma Protein, Histidine-rich Glycoprotein.
279:38267-38276.
2004
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Histidine-rich Glycoprotein Binds to Cell-surface Heparan Sulfate via Its N-terminal Domain following Zn2+ Chelation.
279:30114-30122.
2004
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Highly Flexible Ligand Binding Pocket of Ecdysone Receptor.
279:27211-27218.
2004
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Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes.
279:26581-26587.
2004
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Functional and Structural Characteristics of NY-ESO-1-related HLA A2-restricted Epitopes and the Design of a Novel Immunogenic Analogue.
279:23438-23446.
2004
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Non-fibrillar Components of Amyloid Deposits Mediate the Self-association and Tangling of Amyloid Fibrils.
279:21038-21045.
2004
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A Common Cross-species Function for the Double Epidermal Growth Factor-like Modules of the Highly DivergentPlasmodiumSurface Proteins MSP-1 and MSP-8.
279:20147-20153.
2004
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A Molecular Understanding of Mitoxantrone-DNA Adduct Formation.
279:18814-18823.
2004
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Biogenesis of the Protein Import Channel Tom40 of the Mitochondrial Outer Membrane.
279:18188-18194.
2004
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Properties of GDP-mannose Pyrophosphorylase, a Critical Enzyme and Drug Target inLeishmania mexicana.
279:12462-12468.
2004
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A Role for Apical Membrane Antigen 1 during Invasion of Hepatocytes byPlasmodium falciparumSporozoites.
279:9490-9496.
2004
-
The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition.
279:9298-9305.
2004
-
The Insulin-like Growth Factor 1 Receptor Induces Physiological Heart Growth via the Phosphoinositide 3-Kinase(p110α) Pathway.
279:4782-4793.
2004
-
Three-dimensional Structure of the Barley β-d-Glucan Glucohydrolase in Complex with a Transition State Mimic.
279:4970-4980.
2004
-
Unlike Diablo/smac, Grim Promotes Global Ubiquitination and Specific Degradation of X Chromosome-linked Inhibitor of Apoptosis (XIAP) and Neither Cause Apoptosis.
279:4313-4321.
2004
-
The Elusive Role of the Potential Factor X Cation-binding Exosite-1 in Substrate and Inhibitor Interactions.
279:3671-3679.
2004
-
Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling.
279:2125-2134.
2004
-
Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1.
278:50377-50385.
2003
-
Enzymic, Phylogenetic, and Structural Characterization of the Unusual Papain-like Protease Domain ofPlasmodium falciparumSERA5.
278:48169-48177.
2003
-
Molecular Definition of the Ascorbate-Glutathione Cycle inArabidopsisMitochondria Reveals Dual Targeting of Antioxidant Defenses in Plants.
278:46869-46877.
2003
-
Oncogenic Ki-Ras Inhibits the Expression of Interferon-responsive Genes through Inhibition of STAT1 and STAT2 Expression.
278:46278-46287.
2003
-
Structural Basis for Tetrodotoxin-resistant Sodium Channel Binding by μ-Conotoxin SmIIIA.
278:46805-46813.
2003
-
The 2.0-Å Crystal Structure of eqFP611, a Far Red Fluorescent Protein from the Sea Anemone Entacmaea quadricolor.
278:44626-44631.
2003
-
Superoxide Stimulates a Proton Leak in Potato Mitochondria That Is Related to the Activity of Uncoupling Protein.
278:22298-22302.
2003
-
The Signal Sequence of Exported Protein-1 Directs the Green Fluorescent Protein to the Parasitophorous Vacuole of Transfected Malaria Parasites.
278:6532-6542.
2003
-
Phage-displayed Peptides Bind to the Malarial Protein Apical Membrane Antigen-1 and Inhibit the Merozoite Invasion of Host Erythrocytes.
277:50303-50310.
2002
-
Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry.
277:46487-46492.
2002
-
Environmental Stress Causes Oxidative Damage to Plant Mitochondria Leading to Inhibition of Glycine Decarboxylase.
277:42663-42668.
2002
-
Insertion and Assembly of Human Tom7 into the Preprotein Translocase Complex of the Outer Mitochondrial Membrane.
277:42197-42204.
2002
-
Mixed Lineage Kinase 2 Interacts with Clathrin and Influences Clathrin-coated Vesicle Trafficking.
277:36280-36287.
2002
-
Analysis of the Regulation of the A33 Antigen Gene Reveals Intestine-specific Mechanisms of Gene Expression.
277:34531-34539.
2002
-
Use of Biomolecular Interaction Analysis to Elucidate the Regulatory Mechanism of the Cysteine Synthase Complex fromArabidopsis thaliana.
277:30629-30634.
2002
-
Recombinant CLIC1 (NCC27) Assembles in Lipid Bilayers via a pH-dependent Two-state Process to Form Chloride Ion Channels with Identical Characteristics to Those Observed in Chinese Hamster Ovary Cells Expressing CLIC1.
277:26003-26011.
2002
-
A Metal-binding Member of the Late Embryogenesis Abundant Protein Family Transports Iron in the Phloem of
Ricinus communis
L..
277:25062-25069.
2002
-
Molecular Determinants of the Mechanism Underlying Acceleration of the Interaction between Antithrombin and Factor Xa by Heparin Pentasaccharide.
277:15971-15978.
2002
-
Isolation and Characterization of a Novel Eosinophil-specific Galectin Released into the Lungs in Response to Allergen Challenge.
277:14916-14924.
2002
-
Inhibitory Activity of a Heterochromatin-associated Serpin (MENT) against Papain-like Cysteine Proteinases Affects Chromatin Structure and Blocks Cell Proliferation.
277:13192-13201.
2002
-
GmZIP1 Encodes a Symbiosis-specific Zinc Transporter in Soybean.
277:4738-4746.
2002
-
Human Relaxin Gene 3 (H3) and the Equivalent Mouse Relaxin (M3) Gene.
277:1148-1157.
2002
-
HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins.
277:445-454.
2002
-
Evidence That the Angiotensin IV (AT4) Receptor Is the Enzyme Insulin-regulated Aminopeptidase.
276:48623-48626.
2001
-
Crystal Structure of a Soluble Form of the Intracellular Chloride Ion Channel CLIC1 (NCC27) at 1.4-Å Resolution.
276:44993-45000.
2001
-
Characterization of theDrosophilaCaspase, DAMM.
276:25342-25350.
2001
-
Syntaxin 7 Complexes with Mouse Vps10p Tail Interactor 1b, Syntaxin 6, Vesicle-associated Membrane Protein (VAMP)8, and VAMP7 in B16 Melanoma Cells.
276:19820-19827.
2001
-
The Propeptide of the Transforming Growth Factor-β Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion.
276:16911-16918.
2001
-
Cytosine Methylation Enhances Mitoxantrone-DNA Adduct Formation at CpG Dinucleotides.
276:15953-15960.
2001
-
Determination of the Disulfide Structure andN-Glycosylation Sites of the Extracellular Domain of the Human Signal Transducer gp130.
276:8244-8253.
2001
-
An Essential Role for the Caspase Dronc in Developmentally Programmed Cell Death inDrosophila.
275:40416-40424.
2000
-
Self-association of Human Apolipoprotein E3 and E4 in the Presence and Absence of Phospholipid.
275:36758-36765.
2000
-
The Non-competitive Antagonists 2-Methyl-6-(phenylethynyl)pyridine and 7-Hydroxyiminocyclopropan[b]chromen-1a-carboxylic Acid Ethyl Ester Interact with Overlapping Binding Pockets in the Transmembrane Region of Group I Metabotropic Glutamate Receptors.
275:33750-33758.
2000
-
Isolation and Characterization of a Novel Inducible Mammalian Galectin.
275:32106-32113.
2000
-
The Drosophila caspase DRONC is a glutamate/aspartate protease whose activity is regulated by DIAP1, HID and GRIM.
275:27084-27093.
2000
-
Differential Protein Phosphorylation in 3T3-L1 Adipocytes in Response to InsulinVersusPlatelet-derived Growth Factor.
275:24313-24320.
2000
-
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7 (vol 274, pg 30778, 1999).
275:15600-15600.
2000
-
Erratum: DECAY, a novel Drosophila caspase related to mammalian caspase- 3 and caspase-7 (Journal of Biological Chemistry (1999) 274 (30778-30783)).
275:15600.
2000
-
Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two.
275:9664-9672.
2000
-
Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers.
274:32127-32136.
1999
-
DECAY, a NovelDrosophilaCaspase Related to Mammalian Caspase-3 and Caspase-7.
274:30778-30783.
1999
-
A Novel and Highly Divergent Homolog of Human Eosinophil Granule Major Basic Protein.
274:14464-14473.
1999
-
Fine Structure Analysis of Interaction of FcεRI with IgE.
274:13345-13352.
1999
-
The Carboxyl-terminal Domains of gp130-related Cytokine Receptors Are Necessary for Suppressing Embryonic Stem Cell Differentiation.
274:9729-9737.
1999
-
Disulfide Bond Structure andN-Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor.
274:7207-7215.
1999
-
Characterization of a Novel GDP-mannose:Serine-protein Mannose-1-phosphotransferase fromLeishmania mexicana.
274:6678-6688.
1999
-
Signals Required for the Import and Processing of the Alternative Oxidase into Mitochondria.
274:1286-1293.
1999
-
Erratum: Functional analysis of human mitochondrial receptor Tom20 for protein import into mitochondria (Journal of Biological Chemistry (1998) 273 (26844-26851)).
273:34662.
1998
-
Functional Analysis of Human Mitochondrial Receptor Tom20 for Protein Import into Mitochondria.
273:26844-26851.
1998
-
Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide.
273:22528-22536.
1998
-
The Immunoglobulin-like Module of gp130 Is Required for Signaling by Interleukin-6, but Not by Leukemia Inhibitory Factor.
273:22701-22707.
1998
-
Evidence for the Existence of Distinct Mammalian Cytosolic, Microsomal, and Two Mitochondrial GrpE-like Proteins, the Co-chaperones of Specific Hsp70 Members.
273:21169-21177.
1998
-
Characterization of Aggrecan Retained and Lost from the Extracellular Matrix of Articular Cartilage.
273:17451-17458.
1998
-
Heat Shock Protein 72 Modulates Pathways of Stress-induced Apoptosis.
273:17147-17153.
1998
-
Stage-specific Proteophosphoglycan fromLeishmania mexicanaAmastigotes.
273:13509-13523.
1998
-
Identification and Characterization of Two Distinct Truncated Forms of gp130 and a Soluble Form of Leukemia Inhibitory Factor Receptor α-Chain in Normal Human Urine and Plasma.
273:10798-10805.
1998
-
Analysis of Grb7 Recruitment by Heregulin-activated erbB Receptors Reveals a Novel Target Selectivity for erbB3.
273:7717-7724.
1998
-
Isolation from Phage Display Libraries of Single Chain Variable Fragment Antibodies That Recognize Conformational Epitopes in the Malaria Vaccine Candidate, Apical Membrane Antigen-1.
272:25678-25684.
1997
-
Distinct Roles for Leukemia Inhibitory Factor Receptor α-Chain and gp130 in Cell Type-specific Signal Transduction.
272:19982-19986.
1997
-
Identification, Purification, and Characterization of a Soluble Interleukin (IL)-13-binding Protein.
272:9474-9480.
1997
-
Structural Determinants of the Interaction between the erbB2 Receptor and the Src Homology 2 Domain of Grb7.
272:8490-8497.
1997
-
Visualization of Mitochondrial Protein Import in Cultured Mammalian Cells with Green Fluorescent Protein and Effects of Overexpression of the Human Import Receptor Tom20.
272:8459-8465.
1997
-
Molecular Cloning and Characterization ofPorphyromonas gingivalisLysine-specific Gingipain.
272:1595-1600.
1997
-
gp130-mediated Signal Transduction in Embryonic Stem Cells Involves Activation of Jak and Ras/Mitogen-activated Protein Kinase Pathways.
271:30136-30143.
1996
-
The Disulfide Bond Structure ofPlasmodiumApical Membrane Antigen-1.
271:29446-29452.
1996
-
Glycosylation Defect in Lec1 Chinese Hamster Ovary Mutant Is Due to a Point Mutation inN-Acetylglucosaminyltransferase I Gene.
271:27818-27822.
1996
-
Purification and Characterization of a Novel Endopeptidase in Ragweed (Ambrosia artemisiifolia) Pollen.
271:26227-26232.
1996
-
Purification and Characterization of a Novel Restricted Antigen Expressed by Normal and Transformed Human Colonic Epithelium.
271:25664-25670.
1996
-
Purification and Characterization of a 43-kDa Rotenone-insensitive NADH Dehydrogenase from Plant Mitochondria.
271:23117-23120.
1996
-
Purification and Structural Characterization of a Filamentous, Mucin-like Proteophosphoglycan Secreted byLeishmaniaParasites.
271:21583-21596.
1996
-
Redirected Cytotoxic Effector Function.
271:21214-21220.
1996
-
Influence of Interleukin-6 (IL-6) Dimerization on Formation of the High Affinity Hexameric IL-6·Receptor Complex.
271:20138-20144.
1996
-
Rabbit Polymorphonuclear Neutrophils Form35S-LabeledS-Sulfo-calgranulin C When Incubated with Inorganic [35S]Sulfate.
271:19802-19809.
1996
-
Cloning and Characterization ofGRB14, a Novel Member of theGRB7Gene Family.
271:12502-12510.
1996
-
Adriamycin-induced DNA Adducts Inhibit the DNA Interactions of Transcription Factors and RNA Polymerase.
271:5422-5429.
1996
-
The Interleukin-6 (IL-6) Partial Antagonist (Q159E,T162P)IL-6 Interacts with the IL-6 Receptor and gp130 but Fails to Induce a Stable Hexameric Receptor Complex.
271:5464-5473.
1996
-
Affinity Purification, Overexpression, and Characterization of Chaperonin 10 Homologues Synthesized with and without N-terminal Acetylation.
270:22037-22043.
1995
-
Human Mineralocorticoid Receptor Genomic Structure and Identification of Expressed Isoforms.
270:21016-21020.
1995
-
Multiple Regions of Human FcγRII (CD32) Contribute to the Binding of IgG.
270:21188-21194.
1995
-
Molecular Cloning and Expression of cDNA Encoding the Rat UDP-N-Acetylglucosamine:α-6-D-Mannoside β-1,2-N-Acetylglucosaminyltransferase II.
270:15211-15221.
1995
-
C-terminal Extension of Truncated Recombinant Proteins inEscherichia coliwith a 10Sa RNA Decapeptide.
270:9322-9326.
1995
-
Molecular Cloning and Structural Characterization of the Arg-gingipain Proteinase ofPorphyromonas gingivalis.
270:1007-1010.
1995
-
Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10.
270:1323-1331.
1995
-
High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130.
269:23286-23289.
1994
-
Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum.
269:6955-6961.
1994
-
Identification of the IgG binding site of the human low affinity receptor for IgG FcγRII. Enhancement and ablation of binding by site-directed mutagenesis.
269:15287-15293.
1994
-
Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins.
269:406-411.
1994
-
The cyclophilin component of the unactivated estrogen receptor contains a tetratricopeptide repeat domain and shares identity with p59 (FKBP59).
268:13187-13192.
1993
-
Epidermal growth factor induces serine phosphorylation of stathmin in a human colon carcinoma cell line (LIM 1215).
268:13396-13405.
1993
-
The structure of Leishmania major amastigote lipophosphoglycan.
268:18457-18466.
1993
-
Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line.
267:3262-3267.
1992
-
Purification and structural analysis of a murine chemotactic cytokine (CP- 10) with sequence homology to S100 proteins.
267:7499-7504.
1992
-
Selective suppression of growth factor-induced cell cycle gene expression by Na+/H+ antiport inhibitors.
267:19043-19046.
1992
-
Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents.
267:12307-12310.
1992
-
The purification of a Rap1 GTPase-activating protein from bovine brain cytosol.
267:1546-1553.
1992
-
Upstream sequence elements required for NarL-mediated activation of transcription from the narGHJI promoter of Escherichia coli.
267:14122-14128.
1992
-
Identification of a functional domain of human granulocyte colony-stimulating factor using neutralizing monoclonal antibodies.
266:23815-23823.
1991
-
The major colonic cell mitogen extractable from colonic mucosa is an N terminally extended form of basic fibroblast growth factor.
266:14425-14430.
1991
-
Variants of a Leishmania surface antigen derived from a multigenic family.
266:24477-24484.
1991
-
The β-glucan synthase from Lolium multiflorum. Detergent solubilization, purification using monoclonal antibodies, and photoaffinity labeling with a novel photoreactive pyrimidine analogue of uridine 5'-diphosphoglucose.
266:22569-22581.
1991
-
Structures of the glycoinositolphospholipids from Leishmania major. A family of novel galactofuranose-containing glycolipids.
265:7385-7394.
1990
-
Stimulation of glycine catabolism in isolated perfused rat liver by calcium mobilizing hormones and in isolated rat liver mitochondria by submicromolar concentrations of calcium.
265:1246-1248.
1990
-
THE INTERACTION SITE FOR TAMOXIFEN AZIRIDINE WITH THE BOVINE ESTROGEN-RECEPTOR.
264:13453-13459.
1989
-
A family of glycoinositol phospholipids from Leishmania major. Isolation, characterization, and antigenicity.
264:757-766.
1989
-
Cloning of developmentally regulated genes from Leishmania major and expression following heat induction.
264:4244-4250.
1989
-
Regulation of hepatic glycine catabolism by glucagon.
264:3347-3351.
1989
-
The developmentally regulated P100/11E gene of Leishmania major shows homology to a superfamily of reductase genes.
264:4251-4254.
1989
-
Location of sequences in the nar promoter of Escherichia coli required for regulation by Fnr and NarL.
263:13700-13705.
1988
-
Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists..
262:3440-3443.
1987
-
DNA hypermethylation in sodium butyrate-treated WI-38 fibroblasts.
261:2786-2790.
1986
-
Purification of two forms of colony-stimulating factor from mouse L-cell-conditioned medium.
260:16004-16011.
1985
-
PURIFICATION OF 2 FORMS OF COLONY-STIMULATING FACTOR FROM MOUSE L-CELL-CONDITIONED MEDIUM.
260:6004-6011.
1985
-
Disaggregation of Dictyostelium discoideum cells incubated on immobilized sugars involves negative chemotaxis.
258:13898-13899.
1983
-
DISAGGREGATION OF DICTYOSTELIUM-DISCOIDEUM CELLS INCUBATED ON IMMOBILIZED SUGARS INVOLVES NEGATIVE CHEMOTAXIS.
258:3898-3899.
1983
-
Stereochemistry of beta-, gamma-, and epsilon-ring formation in bacterial C50..
256:11607-11611.
1981
-
Complete amino acid analysis of proteins from a single hydrolysate.
251:1936-1940.
1976
-
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
249:2763-2768.
1974
-
Inhibition by N (phosphonacetyl) L aspartate of aspartate transcarbamylase activity and drug induced cell proliferation in mice.
249:6951-6955.
1974
-
Biosynthesis of pyrimidine nucleotides in mouse salivary glands stimulated with isoproterenol..
248:1196-1202.
1973
-
Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
2017
-
Retraction: Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1 (The Journal of biological chemistry (2006) 281 40 (30152-30165))
2017
-
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.
2016
-
Correction: The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner (Journal of Biological Chemistry)
2015
-
The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.
2013
-
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kB and activation of caspase-8 (vol 286, pg 13282, 2011)
2016
-
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kB and activation of caspase-8 (vol 286, pg 13282, 2011)
2016
-
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappa B and activation of caspase-8 (vol 286, pg 13282, 2011)
2016
has subject area
Identity
International Standard Serial Number (ISSN)
-
0021-9258
-
1067-8816
-
1083-351X
Electronic International Standard Serial Number (EISSN)