selected publications
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academic article
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Luu LCiccotosto GDVella LJSim LCRoisman LCMulthaup GHill AMunter LMCappai R. Amyloid precursor protein dimerisation reduces neurite outgrowth.
Molecular Neurobiology.
56:13-28.
2019
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Clayton ABoilard EBuzas ECheng LManual Falcon-Perez JGardiner CGustafson DGualerzi AHendrix AHoffmann AJones JLasser CLawson CLenassi MNazarenko IO'Driscoll LPink RSiljander PR-MSoekmadji CWauben MWelsh JAWitwer KZheng LNieuwland R. Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles.
Journal of Extracellular Vesicles.
8.
2019
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Low HHoang APushkarsky TDubrovsky LDewar EDi Yacovo M-SMukhamedova NCheng LDowns CSimon GSaumoy MHill AFFitzgerald MLNestel PDart AHoy JBukrinsky MSviridov D. HIV disease, metabolic dysfunction and atherosclerosis: A three year prospective study.
PLoS ONE.
14.
2019
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Yap TSeers CKoo KCheng LVella LJHill AFReynolds ENastri ACirillo NMcCullough M. Non-invasive screening of a microRNA-based dysregulation signature in oral cancer and oral potentially malignant disorders.
Oral Oncology.
96:113-120.
2019
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Nasiri Kenari AKastaniegaard KGreening DWShambrook MStensballe ASim LCHill AF. Proteomic and Post‐Translational Modification Profiling of Exosome‐Mimetic Nanovesicles Compared to Exosomes.
Proteomics.
19:1800161-1800161.
2019
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Tiihonen JKoskuvi MStorvik MHyötyläinen IGao YPuttonen KAGiniatullina RPoguzhelskaya EOjansuu IVaurio OCannon TDLönnqvist JTherman SSuvisaari JKaprio JCheng LHill AFLähteenvuo MTohka JGiniatullin RLehtonen ŠKoistinaho J. Sex-specific transcriptional and proteomic signatures in schizophrenia.
Nature Communications.
10.
2019
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Foers ADChatfield SDagley LFScicluna BJWebb AISim LCHill AFWicks IPPang KC. Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.
Journal of Extracellular Vesicles.
7:1-13.
2018
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Sim LZhao WHill A. Exosomes and their role in the intercellular trafficking of normal and disease associated prion proteins.
Molecular Aspects of Medicine.
60:62-68.
2018
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Thery CWitwer KWAikawa EJose Alcaraz MAnderson JDAndriantsitohaina RAntoniou AArab TArcher FAtkin-Smith GKAyre DCBach J-MBachurski DBaharvand HBalaj LBaldacchino SBauer NNBaxter AABebawy MBeckham CZavec ABBenmoussa ABerardi ACBergese PBielska EBlenkiron CBobis-Wozowicz SBoilard EBoireau WBongiovanni ABorras FEBosch SBoulanger CMBreakefield XBreglio AMBrennan MABrigstock DRBrisson ABroekman MLDBromberg JFBryl-Gorecka PBuch SBuck AHBurger DBusatto SBuschmann DBussolati BBuzas EByrd JBCamussi GCarter DRFCaruso SChamley LWChang Y-TChen CChen SCheng LChin ARClayton AClerici SPCocks ACocucci ECoffey RJCordeiro-da-Silva ACouch YCoumans FAWCoyle BCrescitelli RCriado MFD'Souza-Schorey CDas SChaudhuri ADde Candia PDe Santana Junior EFDe Wever Odel Portillo HADemaret TDeville SDevitt ADhondt BDi Vizio DDieterich LCDolo VDominguez Rubio APDominici MDourado MRDriedonks TAPDuarte FDuncan HMEichenberger RMEkstrom KAndaloussi SELElie-Caille CErdbrugger UFalcon-Perez JMFatima FFish JEFlores-Bellver MForsonits AFrelet-Barrand AFricke FFuhrmann GGabrielsson SGamez-Valero AGardiner CGaertner KGaudin RGho YSGiebel BGilbert CGimona MGiusti IGoberdhan DCGoergens AGorski SMGreening DWGross JCGualerzi AGupta GNGustafson DHandberg AHaraszti RAHarrison PHegyesi HHendrix AHill AFHochberg FHHoffmann KFHolder BHolthofer HHosseinkhani BHu GHuang YHuber VHunt SIbrahim AG-EIkezu TInal JMIsin MIvanova AJackson HKJacobsen SJay SMJayachandran MJenster GJiang LJohnson SMJones JCJong AJovanovic-Talisman TJung SKalluri RKano S-IKaur SKawamura YKeller ETKhamari DKhomyakova EKhvorova AKierulf PKim KPKislinger TKlingeborn MKlinke DJKornek MKosanovic MMKovacs AFKraemer-Albers E-MKrasemann SKrause MKurochkin IKusuma GDKuypers SLaitinen SLangevin SMLanguino LRLannigan JLasser CLaurent LCLavieu GLazaro-Ibanez ELe Lay SLee M-SLee YXFLemos DSLenassi MLeszczynska ALi ITSLiao KLibregts SFLigeti ELim RLim SKLine ALinnemannstoens KLlorente ALombard CALorenowicz MJLorincz AMLotvall JLovett JLowry MCLoyer XLu QLukomska BLunavat TRMaas SLNMalhi HMarcilla AMariani JMariscal JMartens-Uzunova ESMartin-Jaular LMartinez MCMartins VRMathieu MMathivanan SMaugeri MMcGinnis LKMcVey MJMeckes DGMeehan KLMertens IMinciacchi VRMoller AJorgensen MMMorales-Kastresana AMorhayim JMullier FMuraca MMusante LMussack VMuth DCMyburgh KHNajrana TNawaz MNazarenko INejsum PNeri CNeri TNieuwland RNimrichter LNolan JPNolte-'t Hoen ENMHooten NNO'Driscoll LO'Grady TO'Loghlen AOchiya TOlivier MOrtiz AOrtiz LAOsteikoetxea XOstegaard OOstrowski MPark JPegtel DMPeinado HPerut FPfaffl MWPhinney DGPieters BCHPink RCPisetsky DSvon Strandmann EPPolakovicova IPoon IKHPowell BHPrada IPulliam LQuesenberry PRadeghieri ARaffai RLRaimondo SRak JRamirez MRaposo GRayyan MSRegev-Rudzki NRicklefs FLRobbins PDRoberts DDRodrigues SCRohde ERome SRouschop KMARughetti ARussell AESaa PSahoo SSalas-Huenuleo ESanchez CSaugstad JASaul MJSchiffelers RMSchneider RSchoyen THScott AShahaj ESharma SShatnyeva OShekari FShelke GVShetty AKShiba KSiljander PR-MSilva AMSkowronek ASnyder OLSoares RPSodar BWSoekmadji CSotillo JStahl PDStoorvogel WStott SLStrasser EFSwift STahara HTewari MTimms KTiwari STixeira RTkach MToh WSTomasini RTorrecilhas ACPablo Tosar JToxavidis VUrbanelli LVader Pvan Balkom BWMvan der Grein SGVan Deun Jvan Herwijnen MJCVan Keuren-Jensen Kvan Niel Gvan Royen MEvan Wijnen AJHelena Vasconcelos MVechetti IJVeit TDVella LJVelot EVerweij FJVestad BVinas JLVisnovitz TVukman KVWahlgren JWatson DCWauben MHMWeaver AWebber JPWeber VWehman AMWeiss DJWelsh JAWendt SWheelock AMWiener ZWitte LWolfram JXagorari AXander PXu JYan XYanez-Mo MYin HYuana YZappulli VZarubova JZekas VZhang J-YZhao ZZheng LZheutlin ARZickler AMZimmermann PZivkovic AMZocco DZuba-Surma EK. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
Journal of Extracellular Vesicles.
7:1-47.
2018
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McKenzie-Nickson SChan JPerez KHung LWSim LCSedjahtera AGunawan LAdlard PAHayne DJMcInnes LEDonnelly PSFinkelstein DIHill AFBarnham KJ. Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
ACS Chemical Neuroscience.
9:2731-2740.
2018
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Yap TKoo KCheng LVella LJHill AFReynolds ENastri ACirillo NSeers CMcCullough M. Predicting the presence of oral squamous cell carcinoma using commonly dysregulated MicroRNA in oral swirls.
Cancer Prevention Research.
11:491-502.
2018
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Paquet-Fifield SKoh SLSim LCLCBeyit LMShembrey CEMoelck CBehrenbruch CPapin MGironella MGuelfi SNasr RGrillet FPrudhomme MBourgaux J-FCastells APascussi J-MHeriot AGPuisieux ADavis MJPannequin JHill AFSloan EKHollande F. Tight junction protein claudin-2 promotes self-renewal of human colorectal cancer stem-like cells..
Cancer Research.
78:2925-2938.
2018
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Vella LJScicluna BJSim LBawden EGMasters CLAng C-SWillamson NMcLean CBarnham KJHill AF. A rigorous method to enrich for exosomes from brain tissue.
Journal of Extracellular Vesicles.
6:1-13.
2017
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Lunavat TRCheng LEinarsdottir BOOlofsson Bagge RVeppil Muralidharan SSharples RALässer CGho YSHill AFNilsson JALötvall J. BRAF V600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
Proceedings of the National Academy of Sciences of USA.
114:E5930-E5939.
2017
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Quek CBellingham SAJung CHScicluna BJShambrook MCSharples RACheng LHill AF. Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery.
RNA Biology.
14:245-258.
2017
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Van Deun JMestdagh PAgostinis PAkay ÖAnand SAnckaert JMartinez ZABaetens TBeghein EBertier LBerx GBoere JBoukouris SBremer MBuschmann DByrd JBCasert CCheng LCmoch ADaveloose DDe Smedt EDemirsoy SDepoorter VDhondt BDriedonks TAPDudek AElsharawy AFloris IFoers ADGärtner KGarg ADGeeurickx EGettemans JGhazavi FGiebel BKormelink TGHancock GHelsmoortel HHill AHyenne VKalra HKim DKowal JKraemer SLeidinger PLeonelli CLiang YLippens LLiu SLo Cicero AMartin SMathivanan SMathiyalagan PMatusek TMilani GMonguió-Tortajada MMus LMMuth DCNémeth ANolte-'t Hoen ENMO'Driscoll LPalmulli RPfaffl MWPrimdal-Bengtson BRomano ERousseau QSahoo SSampaio NSamuel MScicluna BSoen BSteels ASwinnen JVTakatalo MThaminy SThéry CTulkens JVan Audenhove Ivan der Grein SVan Goethem Avan Herwijnen MJVan Niel GVan Roy NVan Vliet ARVandamme NVanhauwaert SVergauwen GVerweij FWallaert AWauben MWitwer KWZonneveld MIDe Wever OVandesompele JHendrix A. EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.
Nature Methods.
14:228-232.
2017
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Foers ADSim LHill AFWicks IPPang KC. Extracellular vesicles in joint inflammation.
Arthritis and Rheumatology.
69:1350-1362.
2017
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Sisquella XOfir-Birin YPimentel MASim LAbou Karam PSampaio NGPenington JSConnolly DGiladi TScicluna BJSharples RAWaltmann AAvni DSchwartz ESchofield LPorat ZHansen DSPapenfuss ATEriksson EMGerlic MHill AFBowie AGRegev-Rudzki N. Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.
Nature Communications.
8:1-15.
2017
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Sampaio NGSim LEriksson EM. The role of extracellular vesicles in malaria biology and pathogenesis.
Malaria Journal.
16:1-11.
2017
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Vella LJHill AFCheng L. Focus on extracellular vesicles: exosomes and their role in protein trafficking and biomarker potential in Alzheimer's and Parkinson's disease.
International Journal of Molecular Sciences.
17.
2016
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Cheng LQuek CYJHung LWSharples RASherratt NABarnham KJHill AF. Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu-II(atsm).
Scientific Reports.
6.
2016
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Low HCheng LDi Yacovo MSChurchill MJMeikle PBukrinsky MHill AFSviridov D. Lipid metabolism in patients infected with Nef-deficient HIV-1 strain.
Atherosclerosis.
244:22-28.
2016
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Kim D-KLee JKim SRChoi D-SYoon YJKim JHGo GNhung DHong KJang SCKim S-HPark K-SKim OYPark HTSeo JHAikawa EBaj-Krzyworzeka Mvan Balkom BWMBelting MBlanc LBond VBongiovanni ABorras FEBuee LBuzas EICheng LClayton ACocucci EDela Cruz CSDesiderio DMDi Vizio DEkstrom KFalcon-Perez JMGardiner CGiebel BGreening DWGross JCGupta DHendrix AHill AFHill MMNolte-'t Hoen EHwang DWInal JJagannadham MVJayachandran MJee Y-KJorgensen MKim KPKim Y-KKislinger TLasser CLee DSLee Hvan Leeuwen JLener TLiu M-LLotvall JMarcilla AMathivanan SMoller AMorhayim JMullier FNazarenko INieuwland RNunes DNPang KPark JPatel TPocsfalvi Gdel Portillo HPutz URamirez MIRodrigues MLRoh T-YRoyo FSahoo SSchiffelers RSharma SSiljander PSimpson RJSoekmadji CStahl PStensballe ASt pie ETahara HTrummer AValadi HVella LJWai SNWitwer KYanez-Mo MYoun HZeidler RGho YS. EVpedia: a community web portal for extracellular vesicles research.
Bioinformatics.
31:933-939.
2015
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Cheng LDoecke JDSharples RAVillemagne VLFowler CJRembach AMartins RNRowe CCMacaulay SLMasters CLHill AF. Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment.
Molecular Psychiatry.
20:1188-1196.
2015
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Lunavat TRCheng LKim D-KBhadury JJang SCLasser CSharples RALopez MDNilsson JGho YSHill AFLotvall J. Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells - Evidence of unique microRNA cargos.
RNA Biology.
12:810-823.
2015
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Cheng LSun XScicluna BJColeman BMHill AF. Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine.
Kidney International.
86:433-444.
2014
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Cheng LSharples RAScicluna BJHill AF. Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood.
Journal of Extracellular Vesicles.
3:1-14.
2014
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Cheng LQuek CYJSun XBellingham SAHill AF. The detection of microRNA associated with alzheimer's disease in biological fluids using next-generation sequencing technologies.
Frontiers in Genetics.
4.
2013
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Hung LWVillemagne VLCheng LSherratt NAAyton SWhite ARCrouch PJLim SLeong SLWilkins SGeorge JRoberts BRPham CLLLiu XChiu FCKShackleford DMPowell AKMasters CLBush AIO'Keefe GCulvenor JGCappai RCherny RADonnelly PSHill AFFinkelstein DIBarnham KJ. The hypoxia imaging agent Cu II(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
Journal of Experimental Medicine.
209:837-854.
2012
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Cheng LSmith DJAnderson RLNagley P. Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72.
International Journal of Hyperthermia.
27:415-426.
2011
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Cheng LSmith DJAnderson RLNagley P. Modulation of Cellular Hsp72 Levels in Undifferentiated and Neuron-Like SH-SY5Y Cells Determines Resistance to Staurosporine-Induced Apoptosis.
PLoS ONE.
6:e24473-e24473.
2011
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Luu LCiccotosto GDVella LJSim LCRoisman LCMulthaup GHill AMunter LMCappai R. Amyloid precursor protein dimerisation reduces neurite outgrowth.
Molecular Neurobiology.
56:13-28.
2019
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chapter
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Sim LCLCHill AF. Small RNA library construction for exosomal RNA from biological samples for the ion torrent PGM™ and ion S5™ system.
Methods in Molecular Biology.
71-90.
2017
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Sim LCLCHill AF. Small RNA library construction for exosomal RNA from biological samples for the ion torrent PGM™ and ion S5™ system.
Methods in Molecular Biology.
71-90.
2017
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conference paper
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Zhao WUgalde CCollins SLawson VSim LBellingham SHill A. miR-146a regulates cellular and disease associated prion protein isoforms during prion propagation.
Prion.
36-37.
2019
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Foers AChatfield SDagley LScicluna BCheng LHill AWicks IPang K. EXTRACELLULAR VESICLES IN RHEUMATOID ARTHRITIS SYNOVIAL FLUID.
Internal Medicine Journal.
18-18.
2018
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Paquet-Fifield SKoh SLCheng LFailla LMHollande F. Claudin-2: a new regulator of cancer stem cell self-renewal in colorectal cancer.
Annals of Oncology.
2016
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Foers ASim LCLCChatfield SScicluna BHill AFPang KWicks I. Isolating small extracellular vesicles from synovial fluid.
European Journal of Immunology.
895-895.
2016
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Yap TKoo KSim LCLCVella LHill AFSeers CCirillo NNastri AMcCullough M. MicroRNA expression across clinical sample types in oral mucosal disorders.
Oral Diseases.
15-15.
2016
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Zhao WUgalde CCollins SLawson VSim LBellingham SHill A. miR-146a regulates cellular and disease associated prion protein isoforms during prion propagation.
Prion.
36-37.
2019
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other publication
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Clayton ABuschmann DByrd JBCarter DRFCheng LCompton CDaaboul GDevitt AFalcon-Perez JMGardiner CGustafson DHarrison PHelmbrecht CHendrix AHill AHoffman AJones JCKalluri RKang JYKirchner BLässer CLawson CLenassi MLevin CLlorente AMartens-Uzunova ESMöller AMusante LOchiya TPink RCTahara HWauben MHMWebber JPWelsh JAWitwer KWYin HNieuwland R. Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.
Journal of Extracellular Vesicles.
1473707-1473707.
2018
Full text if available
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Clayton ABuschmann DByrd JBCarter DRFCheng LCompton CDaaboul GDevitt AFalcon-Perez JMGardiner CGustafson DHarrison PHelmbrecht CHendrix AHill AHoffman AJones JCKalluri RKang JYKirchner BLässer CLawson CLenassi MLevin CLlorente AMartens-Uzunova ESMöller AMusante LOchiya TPink RCTahara HWauben MHMWebber JPWelsh JAWitwer KWYin HNieuwland R. Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.
Journal of Extracellular Vesicles.
1473707-1473707.
2018