Lee-Ann's research interests include the histories of mental health and disability, gender history and the history of work. These interests intersect in her book Attending Madness: At Work in the Australian Colonial Asylum. A history of asylum work and workers in colonial Australia, it considers not only who attendants were and why they worked in the asylum, but how they and others understood what it was to be a 'good' attendant.
Lee-Ann was an Australian Research Council (ARC) Post-doctoral Fellow (Industry) on an ARC-Linkage Project at La Trobe which researched the history of Kew Cottages, Australia's first purpose-built institution for people with intellectual disability. She has published on aspects of the Cottages' history and collaborated with other researchers on the project to create a website that allows visitors to explore the institution's history. Lee-Ann also worked as an expert researcher on an ARC-Linkage Project at the University of Melbourne, researching the large collection of objects from Victoria's now-closed mental hospitals held by Museum Victoria.
Lee-Ann is currently a researcher on Professor Diane Kirkby's ARC-Linkage Project, which explores the contribution of Australian maritime unionists to the development of international standards for the world's seafarers, while continuing her research on the histories of mental health and disability.