selected publications
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academic article
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Buskes MJHarvey KLRichards BJKalhor RChristoff RMGardhi CKLittler DRCope EDPrinz BWeiss GEO'Brien NJCrabb BSDeady LWGilson PRAbbott BM. Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation.
Organic and Biomolecular Chemistry.
14:4617-4639.
2016
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O’Brien NJBrzozowski MBuskes MJDeady LWAbbott BM. Synthesis and biological evaluation of 2-anilino-4-substituted-7H-pyrrolopyrimidines as PDK1 inhibitors.
Bioorganic and Medicinal Chemistry.
22:3879-3886.
2014
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O'Brien NJBrzozowski MWilson DJDDeady LWAbbott BM. Synthesis and biological evaluation of substituted 2-anilino-7H-pyrrolopyrimidines as PDK1 inhibitors.
Tetrahedron.
70:4947-4956.
2014
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O’Brien NJBrzozowski MWilson DJDDeady LWAbbott BM. Synthesis and biological evaluation of substituted 3-anilino-quinolin-2(1H)-ones as PDK1 inhibitors.
Bioorganic and Medicinal Chemistry.
22:3781-3790.
2014
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O'Brien NJAmran SMedan JCleary BDeady LWJennings IGThompson PEAbbott BM. Potent Inhibitors of Phosphatidylinositol 3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms.
ChemMedChem: chemistry enabling drug discovery.
8:914-918.
2013
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Deady LWDevine SM. Novel annulated products from aminonaphthyridinones.
Tetrahedron.
62:2313-2320.
2006
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Deady LWRogers ML. Novel derivatives of the benzo[b][1,6]naphthyridine system.
Journal of Heterocyclic Chemistry: international journal.
43:405-416.
2006
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Bray PGDeed SFox EKalkanidis MMungthin MDeady LWTilley L. Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum.
Biochemical Pharmacology.
70:1158-1166.
2005
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Bu XChen JDeady LWSmith CLBaguley BCGreenhalgh DYang SDenny WA. Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]carboxamide derivatives of 7-oxo-7H-benz[de]anthracene, 7-oxo-7H-naphtho[1,2,3-de]quinoline, and 7-oxo-7H-benzo[e]perimidine.
Bioorganic and Medicinal Chemistry.
13:3657-3665.
2005
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Deady LWRogers MLZhuang LBaguley BCDenny WA. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridin-(5H)ones.
Bioorganic and Medicinal Chemistry.
13:1341-1355.
2005
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Deady LWDevine SM. Synthesis and reactivity of some imidazo-, triazolo- and tetrazolo-isoquinoline derivatives.
Journal of Heterocyclic Chemistry: international journal.
41:549-555.
2004
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Kalkanidis MKlonis NTschan SDeady LWTilley L. Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites.
Biochemical Pharmacology.
67:1347-1353.
2004
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Deady LWHughes ABKlonis NQuazi NHTilley LM. Synthesis of a Far Red Absorbing Thiobarbituric Acid Oxonol Derivative as a Fluorescent Probe for Biological Applications.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
33:4269-4277.
2003
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Deady LWDevine SMRogers ML. A CONVENIENT PROCEDURE FOR INDIRECT OXIDATION OF AROMATIC METHYL GROUPS TO ALDEHYDES AND CARBOXYLIC ACIDS.
Organic Preparations and Procedures International.
35:627-630.
2003
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Klonis NQuazi NHDeady LWHughes ABTilley L. Characterization of a series of far-red-absorbing thiobarbituric acid oxonol derivatives as fluorescent probes for biological applications.
Analytical Biochemistry.
317:47-58.
2003
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May BCHFafarman ATHong SBRogers MDeady LWPrusiner SBCohen FE. Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.
Proceedings of the National Academy of Sciences of USA.
100:3416-3421.
2003
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Deady LWRodemann TZhuang LBaguley BCDenny WA. Synthesis and Cytotoxic Activity of Carboxamide Derivatives of Benzo[b][1,6]naphthyridines.
Journal of Medicinal Chemistry.
46:1049-1054.
2003
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Deady LWSmith CL. Tetracycle Formation from the Reaction of Acetophenones with 1-Aminoanthraquinone, and Further Annulation of Pyridine and Diazepine Rings.
Australian Journal of Chemistry: an international journal for chemical science.
56:1219-1219.
2003
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Chen JDeady LWKaye AJFinlay GJBaguley BCDenny WA. Synthesis and cytotoxic activity of N -(2-Diethylamino)ethylcarboxamide and other derivatives of 10 H -Quindoline.
Bioorganic and Medicinal Chemistry.
10:2381-2386.
2002
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Kalkanidis MKlonis NTilley LDeady LW. Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of β-haematin.
Biochemical Pharmacology.
63:833-842.
2002
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Deady LWGaname DQuazi NHZanatta SD. On The Synthesis of Pyridinylthiobarbituric Acids.
Australian Journal of Chemistry: an international journal for chemical science.
55:287-287.
2002
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Bu XChen JDeady LWDenny WA. Synthesis and cytotoxicity of potential anticancer derivatives of pyrazolo[3,4,5-kl]acridine and indolo[2,3-a]acridine.
Tetrahedron.
58:175-181.
2002
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Deady LWRodemann T. The reaction of homophthalic acid and some aza analogues with vilsmeier reagent: a reinvestigation.
Journal of Heterocyclic Chemistry: international journal.
38:1185-1190.
2001
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Ayad FTilley LDeady LW. Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines.
Bioorganic and Medicinal Chemistry Letters.
11:2075-2077.
2001
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Bu XDeady LWFinlay GJBaguley BCDenny WA. Synthesis and Cytotoxic Activity of 7-Oxo-7H-dibenz[f,ij]isoquinoline and 7-Oxo-7H-benzo[e]perimidine Derivatives.
Journal of Medicinal Chemistry.
44:2004-2014.
2001
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Deady LWDesneves JJ. Kaye AJ. Finlay GC. Baguley BA. Denny W. Positioning of the Carboxamide Side Chain in 11-Oxo-11 H -indeno[1,2- b ]quinolinecarboxamide Anticancer Agents: Effects on Cytotoxicity.
Bioorganic and Medicinal Chemistry.
9:445-452.
2001
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Klonis NWang HQuazi NHCasey JLNeumann GMHewish DRHughes ABDeady LWTilley L. Characterization of a Series of Far Red Absorbing Perylene Diones: A New Class of Fluorescent Probes for Biological Applications.
Journal of Fluorescence.
11:1-11.
2001
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Deady LWSette RMD. Lithiation of pivaloylamino derivatives of dibenzofuran and 9-methylcarbazole.
Australian Journal of Chemistry: an international journal for chemical science.
54:177-177.
2001
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Deady LWRodemann T. Reduced Benzimidazo[2,1-a]isoquinolines. Synthesis and Cytotoxicity Studies.
Australian Journal of Chemistry: an international journal for chemical science.
54:529-529.
2001
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Deady LWSmith CL. The preparation of substituted isochromans and 1,2,3,4-tetrahydroisoquinolines by reduction of unsaturated precursors.
Australian Journal of Chemistry: an international journal for chemical science.
54:135-135.
2001
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Deady LWRodemann TFinlay GJBaguley BCDenny WA. Synthesis and cytotoxic activity of carboxamide derivatives of benzimidazo[2,1-a]isoquinoline and pyrido [3′, 2′: 4,5] imidazo [2,1 -a] isoquinoline.
Oncology Research.
15:339-346.
2000
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Chen JDeady LWDesneves JKaye AJFinlay GJBaguley BCDenny WA. Synthesis of Substituted Indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of Structure–Activity Relationships for Cytotoxicity.
Bioorganic and Medicinal Chemistry.
8:2461-2466.
2000
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Deady LWDesneves JTilley LM. A cinchonidine derivative for photoaffinity labelling of proteins.
Journal of Labelled Compounds and Radiopharmaceuticals.
43:977-981.
2000
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Deady LWBaker SJYoung DW. Synthesis of [1-2H]- and [3-2H]-guanosine.
Journal of Labelled Compounds and Radiopharmaceuticals.
43:1023-1032.
2000
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Deady LWDesneves JKaye AJFinlay GJBaguley BCDenny WA. Synthesis and antitumor activity of some indeno[1,2- b ]quinoline-based bis carboxamides.
Bioorganic and Medicinal Chemistry.
8:977-984.
2000
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Daoud RDesneves JDeady LWTilley LScheper RJGros PGeorges E. The Multidrug Resistance Protein Is Photoaffinity Labeled by a Quinoline-Based Drug at Multiple Sites†.
Biochemistry.
39:6094-6102.
2000
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Deady LWHughes ABMahadevan IBQuazi NHTilley LM. Far-Red Dibenzo[a,j]Perylene-8,16-Dione Dyes as Fluorescent Enzyme Substrates and Tags for Biomolecules.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
30:803-820.
2000
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Bu XDeady LWDenny WA. Synthesis and cytotoxic activity of N-[2-(dimethylamino)ethyl] carboxamide derivatives of benzofuro[2,3-b]quinoline, 6H-quinindoline, indeno[2,1-b]quinoline and [1]benzothieno[2,3-b]quinoline.
Australian Journal of Chemistry: an international journal for chemical science.
53:143-143.
2000
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Bu XDeady LW. A Preparation Of Methyl 2-amino-3-formylbenzoate and its use in Friedlander Synthesis.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
29:4223-4233.
1999
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Deady LWDesneves JKaye AJThompson MFinlay GJBaguley BCDenny WA. Ring-substituted 11-oxo-11 H -indeno[1,2- b ]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA.
Bioorganic and Medicinal Chemistry.
7:2801-2809.
1999
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Ciarrocchi GMacPhee DGDeady LWTilley L. Specific Inhibition of the Eubacterial DNA Ligase by Arylamino Compounds.
Antimicrobial Agents and Chemotherapy.
43:2766-2772.
1999
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Deady LWRodemann T. Synthesis of perimidine and fused perimidine derivatives from reaction of 1,8-naphthalenediamine with an iminoisocoumarin.
Journal of Heterocyclic Chemistry: international journal.
35:1417-1419.
1998
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Chen JDeady LW. Synthesis of some quinolizine derivatives.
Tetrahedron.
54:2785-2794.
1998
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Deady LWLoria PMRodemann T. Studies on the Synthesis of Benzimidazo[2,1-a]isoquinolines.
Australian Journal of Chemistry: an international journal for chemical science.
51:941-941.
1998
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Vezmar MDeady LWTilley LGeorges E. The Quinoline-Based Drug,N-{4-[1-hydroxy-2-(dibutylamino)ethyl] quinolin-8-yl}-4-azidosalicylamide, Photoaffinity Labels the Multidrug Resistance Protein (MRP) at a Biologically Relevant Site.
Biochemical and Biophysical Research Communications.
241:104-111.
1997
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Chen J-JDeady LWMackay MF. Synthesis of some acridone alkaloids and related compounds.
Tetrahedron.
53:12717-12728.
1997
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Simpson RMenting JGTTilley LDeady LWNg KRichard J SimpsonCowman AFFoley M. The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum.
Molecular and Biochemical Parasitology.
88:215-224.
1997
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Deady LWKaye AJFinlay GJBaguley BCDenny WA. Synthesis and Antitumor Properties ofN-[2-(Dimethylamino)ethyl]carboxamide Derivatives of Fused Tetracyclic Quinolines and Quinoxalines: A New Class of Putative Topoisomerase Inhibitors.
Journal of Medicinal Chemistry.
40:2040-2046.
1997
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Chen JDeady LW. A Versatile Synthesis of Acridine-1,9-Diones.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
27:95-106.
1997
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Deady LWKaye AJ. Fused Tetracyclic Quinoxalines from Reactions of o-Phenylenediamines in Polyphosphoric Acid.
Australian Journal of Chemistry: an international journal for chemical science.
50:473-473.
1997
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Deady LWCowman, AFDeady, LWDeharo, EDesneves JTilley L. Synthesis and Activity of Some Antimalarial Bisquinolinemethanols.
Australian Journal of Chemistry: an international journal for chemical science.
50:1091-1091.
1997
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Deady LWFoley MDesneves J. Photoaffinity labeling of mefloquine-binding proteins in human serum, uninfected erythrocytes and Plasmodium falciparum-infected erythrocytes.
Molecular and Biochemical Parasitology.
82:181-194.
1996
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Raynes KFoley MTilley LDeady LW. Novel bisquinoline antimalarials.
Biochemical Pharmacology.
52:551-559.
1996
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Deady LWLoria PMQuazi NH. Fused Isoquinoline Systems From Reactions of an Iminoisocoumarin With Nitrogen Nucleophiles.
Australian Journal of Chemistry: an international journal for chemical science.
49:485-485.
1996
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Madden JECardwell TJCattrall RWDeady LW. Nafion-based optode for the detection of metal ions in flow analysis.
Analytica Chimica Acta.
319:129-134.
1996
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Deady LWZhe Xiong LNurul Huda QLeslie W. DGideon M. P. Selective Inhibition of Cyclic AMP-Dependent Protein Kinase by Isoquinoline Derivatives.
Biological Chemistry Hoppe-Seyler.
377:373-384.
1996
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Coppel RLDeady LWLoria PMOlden DCTurnidge JD. Synthesis and Antibacterial Activity of Some 'Bisquinolones'.
Australian Journal of Chemistry: an international journal for chemical science.
49:255-255.
1996
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Deady LWQuazi NH. 13C NMR in the Structural Assignment of Fused Furoxans.
Spectroscopy Letters: an international journal for rapid communication.
28:1033-1040.
1995
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Deady LWCattrall RCardwell TBates M. A polymer membrane potentiometric sensor for silver.
Talanta.
42:999-1004.
1995
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Deady LWDesneves J. AN IMPROVED PROCEDURE FOR THE PREPARATION OF ARYLOXIRANES.
Organic Preparations and Procedures International.
27:219-221.
1995
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Deady LWQuazi NH. Acetylation of α-Cyano-o-tolunitrile: A Reinvestigation and Convenient Synthesis of Isoquinolines.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
25:309-320.
1995
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Raynes KGalatis DCowman AFTilley LDeady LW. Synthesis and Activity of Some Antimalarial Bisquinolines.
Journal of Medicinal Chemistry.
38:204-206.
1995
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Chen QDeady LW. 1H NMR Studies on the Methylation, Protonation, and Hydration Sites in Some Benzo[b]Naphthyridines (Azaacridines).
Spectroscopy Letters: an international journal for rapid communication.
27:1461-1479.
1994
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Chen QDeady LWPolya GM. Inhibition of wheat embryo calcium-dependent protein kinase by acridines and azaacridines.
Phytochemistry.
36:1153-1159.
1994
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Deady LWQuazi NH. Annulation reactions of 3-aminoisoquinolin-l(2H)-one. Synthesis of pyrimido[1,2-b]isoquinolines, pyrido-[2,3-c]isoquinolines and pyrrolo[2,3-c]isoquinolines.
Journal of Heterocyclic Chemistry: international journal.
31:793-796.
1994
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Foley MDeady LWNg KCowman AFTilley L. Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum.
Journal of Biological Chemistry.
269:6955-6961.
1994
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Chen QDeady LWBaguley BCDenny WA. Electron-Deficient DNA Intercalating Agents as Antitumor Drugs: Aza Analogs of the Experimental Clinical Agent N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide.
Journal of Medicinal Chemistry.
37:593-597.
1994
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Chen QDeady LWPolya GM. Differential Inhibition of Cyclic AMP-Dependent Protein Kinase, Myosin Light Chain Kinase and Protein Kinase C by Azaacridine and Acridine Derivatives.
Biological Chemistry Hoppe-Seyler.
375:223-236.
1994
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Cherubim PDeady LWDorkos MQuazi NHBaguley BCDenny WA. Synthesis and biological evaluation of phenanthrene-derived carboxamides as cytotoxic agents.
Oncology Research.
8:429-438.
1993
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Cardwell TJCattrall RWDeady LWDorkos MO'Connell GR. A fast response membrane-based pH indicator optode.
Talanta.
40:765-768.
1993
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Chen QPDeady LWMackay MF. A Comparison of Chemical Reactivity in Some Benzo[b]Naphthyridines (Azaacridines).
Australian Journal of Chemistry: an international journal for chemical science.
46:1909-1909.
1993
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Deady LWQuazi NH. Chemistry of Some [1,2,5]Oxadiazolo[3,4-c]isoquinolines and N-Oxides.
Australian Journal of Chemistry: an international journal for chemical science.
46:411-411.
1993
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Chen QPDeady LW. Synthesis of Some Benzo[b][1,6]naphthyridines and Benzo[b][1,7]naphthyridines.
Australian Journal of Chemistry: an international journal for chemical science.
46:987-987.
1993
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Deady LWDesneves JRoss AC. Synthesis of some 11H-indeno[1,2-b]quinoxalin-11-ones.
Tetrahedron.
49:9823-9828.
1993
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Chen QDeady LW. Synthesis of some benzo[b][1,8] and [1,5]naphthyridines.
Journal of Heterocyclic Chemistry: international journal.
29:1197-1201.
1992
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Argiropoulos GBates MRMCherubim PDeady LWGanakas AMBaguley BCDenny WA. Cytotoxic and DNA binding properties of aminoalkyl derivatives of di- and triazaphenanthrenes.
Oncology Research.
7:285-296.
1992
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Cardwell TJCattrall RWDeady LWMurphy KA. Investigation of the Range of a Plastic pH Sensor Based on a Dibasic Ionophore.
Australian Journal of Chemistry: an international journal for chemical science.
45:435-435.
1992
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Cardwell TJCattrall RWDeady LWMurphy KATan SS. Potentiometric Sensors Based on Macrocyclic Ligands: 1,8-Naphthyridine and 1,10-Phenanthroline Derivatives.
Australian Journal of Chemistry: an international journal for chemical science.
45:983-983.
1992
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Deady LWQuazi NH. Synthesis of Pyrazino[2,3-c]isoquinolinecarboxylic Acids and Related Compounds.
Australian Journal of Chemistry: an international journal for chemical science.
45:2083-2083.
1992
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Bates MRMCardwell TJCattrall RWDeady LWMurphy K. Studies on Cation Selectivities of Some Pyridine-Based Ionophores for Use in Polymer Membrane Chemical Sensors.
Australian Journal of Chemistry: an international journal for chemical science.
44:1603-1603.
1991
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Argiropoulos GDeady LWDorkos M. Synthesis and Further Ring-Forming Reactions of a New 3-Amino-isoquinoline-4-carbaldehyde.
Australian Journal of Chemistry: an international journal for chemical science.
44:481-481.
1991
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Bates MRMDeady LWMackay MF. A New Synthesis of Pyrazino[2,3-c]isoquinolines.
Australian Journal of Chemistry: an international journal for chemical science.
43:179-179.
1990
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Cherubim PDeady LW. Nucleophilic Substitution Reactions in Benzo[C][1,8]naphthyridines. II..
Australian Journal of Chemistry: an international journal for chemical science.
43:1469-1469.
1990
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Deady LWGanakas AMOng BH. Ethoxycarbonylation of α-Cyano-o-toluonitrile and Cyclization to Isoquinolines and Pyrimido[4,5-c]isoquinolines.
Australian Journal of Chemistry: an international journal for chemical science.
42:1029-1029.
1989
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Deady LWMackay MFWerden DM. Reactions of some quinazoline compounds with ethoxymethylenemalonic acid derivatives.
Journal of Heterocyclic Chemistry: international journal.
26:161-168.
1989
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Cattrall RWDeady LWTan SSHamilton IC. A cheap alternative to valinomycin for certain analyses with the potassium ion-selective electrode.
Analytica Chimica Acta.
208:283-286.
1988
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Chandler CJDeady LWReiss JA. Cation-Binding Properties of Macrocyclic Polyether and Polythioether Diesters and Dithioesters From 1,10-Phenanthrolines and 1,8-Naphthyridines.
Australian Journal of Chemistry: an international journal for chemical science.
41:1051-1051.
1988
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Butt GLDeady LWMackay MF. Preparation and stereochemistry of methyl 3-(and 4)-p-chlorothiophenoxy-1-methylpiperidine-4-(and 3)-carboxylates, and cyclization to benzothiopyranopyridinones.
Journal of Heterocyclic Chemistry: international journal.
25:321-326.
1988
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Deady LWWerden DM. New syntheses of acridin-9-ones, benzo[c]quinolizin-6-ones, pyrrolo[1,2-a]quinoline-1,5-diones, and some related tetracyclic compounds.
Journal of Organic Chemistry.
52:3930-3932.
1987
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Deady LWWerden DM. A Convenient Synthesis of Pyrrolo[1,2-a]quinoline-1,5-diones and Acridine-1,9-diones.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
17:319-328.
1987
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Chandler CJDeady LWReiss JA. Macrocyclic polyether- and polythioether-diesters and dithioesters from 1,10-phenanthroline-2,9-dicarboxylic acid.
Journal of Heterocyclic Chemistry: international journal.
23:1327-1330.
1986
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Deady LWKachab EH. A Synthesis of 1-Methoxyisoquinoline-3,4-Diamine and Some Derived Imidazo[4,5-C]Isoquinolines.
Australian Journal of Chemistry: an international journal for chemical science.
39:2089-2089.
1986
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Deady LWWerden DM. Nucleophilic-Substitution Reactions in Benzo[C][1,8]Naphthyridines.
Australian Journal of Chemistry: an international journal for chemical science.
39:667-667.
1986
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Deady LWBuckley PDBennett AFBlackwell LF. Kinetics of inhibition and hysteresis of sheep liver cytoplasmic aldehyde dehydrogenase with glyoxylic acid: Further evidence relating to the two-site model for aldehyde oxidation.
Archives of Biochemistry and Biophysics.
243:586-597.
1985
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Butt GLDeady LW. Addition reactions of thiophenols with dihydro- and tetrahydropyridinecarbonitriles. A comparison with reactions of phenols.
Journal of Heterocyclic Chemistry: international journal.
21:981-984.
1984
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Deady LW. A synthesis of Benzo[c][1,8]naphthyridinones: an exception to the Knorr reaction.
Australian Journal of Chemistry: an international journal for chemical science.
37:1135-1135.
1984
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Deady LWFinlayson WL. Reaction with acetic anhydride as a method for estimating the basicity of exocyclic amino groups in nitrogen heterocycles.
Australian Journal of Chemistry: an international journal for chemical science.
37:1625-1625.
1984
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Deady LWPayne M. A synthesis of 6- and 4-hydroxymethyl derivatives of pyridin-3-ols.
Australian Journal of Chemistry: an international journal for chemical science.
36:2565-2565.
1983
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Blackwell LFBennett AFCrow KEBuckley PDDeady LW. A two-site model for the esterase and dehydrogenase activities of sheep liver aldehyde dehydrogenase.
Pharmacology, Biochemistry and Behavior.
18:83-87.
1983
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Deady LWFinlayson WL. Catalysis by α-substituted pyridines in the hydrolysis of aryl acetates and acetic anhydride.
Australian Journal of Chemistry: an international journal for chemical science.
36:1951-1951.
1983
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Deady LWKorytsky OL. The effect of acid concentration on the pyridine nitramine rearrangement: an N.M.R. study.
Australian Journal of Chemistry: an international journal for chemical science.
36:1159-1159.
1983
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Chandler CJDeady LWReiss JATzimos V. The synthesis of macrocyclic polyether-diesters incorporating 1,10-phenanthrolino and 1,8-naphthyridino subunits.
Journal of Heterocyclic Chemistry: international journal.
19:1017-1019.
1982
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Deady LWKorytsky OL. Kinetic studies on the mechanism of the nitraminopyridine rearrangement.
Australian Journal of Chemistry: an international journal for chemical science.
35:2035-2035.
1982
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Deady LWStanborough MS. Kinetics and mechanism of the reaction of pyridinamine 1-oxides with acetylating agents in water and aprotic solvents.
Australian Journal of Chemistry: an international journal for chemical science.
35:1841-1841.
1982
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Butt GLDeady LWMackay MFSadek M. Novel products from attempted michael addition to 1-methyl-1,2,5,6-tetrahydropyridine-4-carbonitrile.
Tetrahedron Letters.
23:4485-4488.
1982
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Deady LWKorytsky OLRowe JE. Substituent effects on the isomer ratios in the rearrangement of some 2- and 4-nitraminopyridines.
Australian Journal of Chemistry: an international journal for chemical science.
35:2025-2025.
1982
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Chandler CJDeady LWReiss JA. Synthesis of some 2,9-disubstituted-1,10-phenanthrolines.
Journal of Heterocyclic Chemistry: international journal.
18:599-601.
1981
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Deady LW. A search for lone-pair interactions in forward and reverse Menschutkin reactions of some diaza heterocycles.
Australian Journal of Chemistry: an international journal for chemical science.
34:163-163.
1981
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Deady LW. Lone-pair cooperativity in the N-alkylation of some derivatives of 2,2'-biimidazole.
Australian Journal of Chemistry: an international journal for chemical science.
34:2569-2569.
1981
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Clark GJDeady LW. Synthetic uses of the sequential ring positional reactivity in Pyridin-3-ol and derivatives.
Australian Journal of Chemistry: an international journal for chemical science.
34:927-927.
1981
Full text if available -
Broxton TJDeady LWLim RHK. The partitioning of the tetrahedral intermediate from the basic methanolysis of ethyl N-aryl-N-methylcarbamates.
Australian Journal of Chemistry: an international journal for chemical science.
34:1993-1993.
1981
Full text if available -
Deady LWStanborough MS. The synthesis of 2-heteroarylimidazo[1,2-a]pyridin-3-ols and related compounds.
Australian Journal of Chemistry: an international journal for chemical science.
34:1295-1295.
1981
Full text if available -
Broxton TJDeady LWRowe JE. Basic methanolysis of N-aryl-N-phenylbenzamides.
Journal of Organic Chemistry.
45:2404-2408.
1980
Full text if available -
Deady LWFinlayson WL. Studies on a General Method for the Demethylation of Quaternized Nitrogen Heterocycles.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
10:947-950.
1980
Full text if available -
Deady LWFinlayson WL. The aminolysis of p-nitrophenyl acetate by aminopyridines. Mechanisms in aqueous and aprotic solvents.
Australian Journal of Chemistry: an international journal for chemical science.
33:2441-2441.
1980
Full text if available -
Deady LWSlanborough MS. A Synthesis of 2-Arylimidazo[1,2-a]pyridin-3-ols.
Journal of Heterocyclic Chemistry: international journal.
16:187-188.
1979
Full text if available -
Deady LWKorytsky OL. A re-evaluation of the role of triphenylphosphine in demethylation of quaternary heterocyclic salts.
Tetrahedron Letters.
20:451-452.
1979
Full text if available -
Deady LWStillman DC. Mechanisms for the Benzoylation of 2-Aminopyridine.
Australian Journal of Chemistry: an international journal for chemical science.
32:381-381.
1979
Full text if available -
Deady LWGrimmett MRPotts CH. Studies on the mechanism of the nitraminopyridine rearrangement.
Tetrahedron.
35:2895-2900.
1979
Full text if available -
Davis MDeady LWPaproth TGDoyle RR. Tested demonstrations: The nitration of alkylbenzenes: A lecture demonstration.
Journal of Chemical Education.
55:34.
1978
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Broxton TJDeady LWPang Y-T. Basic methanolysis of benzoylmethylaminopyridines and their N-oxide and methyl quaternary derivatives.
Journal of Organic Chemistry.
43:2023-2026.
1978
Full text if available -
Broxton TJDeady LWRowe JE. Basic methanolysis of N-Aryl-N-methylthiobenzamides.
Australian Journal of Chemistry: an international journal for chemical science.
31:1731-1731.
1978
Full text if available -
Deady LWStillman DC. Mechanisms for the acetylation of aminopyridines.
Australian Journal of Chemistry: an international journal for chemical science.
31:1725-1725.
1978
Full text if available -
Broxton TJDeady LWDuddy NW. Micellar catalysis of anilide hydrolysis.
Australian Journal of Chemistry: an international journal for chemical science.
31:1525-1525.
1978
Full text if available -
Zoltewicz JADeady LW. Quaternization of Heteroaromatic Compounds: Quantitative Aspects.
Advances in Heterocyclic Chemistry.
22:71-121.
1978
Full text if available -
Broxton TJDeady LWPang Y-T. Intramolecular catalysis in the basic methanolysis of N-2-pyridinylbenzamide and related compounds.
Journal of the American Chemical Society.
99:2268-2271.
1977
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Deady LWFinlayson WLPotts CH. Alkylation of salts of pyridinols, quinolinols and isoquinolinols.
Australian Journal of Chemistry: an international journal for chemical science.
30:1349-1349.
1977
Full text if available -
Deady LW. Ring Nitrogen Oxidation of Amino Substituted Nitrogen Heterocycles with m-Chloroperbenzoic Acid.
Synthetic Communications: an international journal for rapid communication of synthetic organic chemistry.
7:509-514.
1977
Full text if available -
Deady LWYusoff NI. The methylation of 8-Aminoquinoline.
Journal of Heterocyclic Chemistry: international journal.
13:125-126.
1976
Full text if available -
Deady LWStillman DC. Steric effects in quaternizations. Alkylation of pyridine, thiazole, isothiazole and some benzologues with methyl, ethyl and isopropyl iodides.
Australian Journal of Chemistry: an international journal for chemical science.
29:1745-1745.
1976
Full text if available -
Deady LWHarrison PMTopsom RD. Frequency and intensity measurements of the carbonyl stretching vibration in substituted methyl benzoates and pyridine carboxylates.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.
31:1671-1676.
1975
Full text if available -
Deady LWHarrison PMTopsom RD. Infrared spectroscopy as a measure of proximity effects—ortho-substituted benzonitriles and alpha-substituted ortho toluonitriles.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.
31:1665-1670.
1975
Full text if available -
Broxton TJDeady LW. Basic methanolysis of anilides. Evidence for the mechanism applying to the special case of N-methyl-4'-nitroanilides.
Journal of Organic Chemistry.
40:2906-2910.
1975
Full text if available -
Huffadine ASPeake BMDeady LW. Electron spin resonance studies of aromatic hydrocarbon radical ions. Part IV. t-Butylacenaphthene anions.
Journal of the Chemical Society, Perkin Transactions 2.
1263-1263.
1975
Full text if available -
Deady LWHarrison PMTopsom RD. Proximity effects in pyridines. Proton chemical shifts in substituted methyl pyridinecarboxylates.
Magnetic Resonance in Chemistry.
7:41-45.
1975
Full text if available -
Deady LWMcLoughlin RGGrimmett MR. Rates of N-methylation of N-arylpyrazoles.
Australian Journal of Chemistry: an international journal for chemical science.
28:1861-1861.
1975
Full text if available -
Deady LW. Reactions of the isomeric pyridinecarboxylic acid 1-oxides with dimethyl sulphate.
Tetrahedron.
31:1217-1218.
1975
Full text if available -
Broxton TJCarolane CJDeady LW. The basic methanolysis of some substituted 4'-nitrobenzanilides.
Australian Journal of Chemistry: an international journal for chemical science.
28:451-451.
1975
Full text if available -
Davis MDeady LWHomfeld EPogany S. The chemistry of 2,1-benzisothiazoles. VIII. Tautomerism of 2,1-Benzisothiazolin-3-one and the preparation of N- and O-alkylated derivatives.
Australian Journal of Chemistry: an international journal for chemical science.
28:129-129.
1975
Full text if available -
Broxton TJDeady LWPang YT. The effect of DMSO on the basic methanolysis of benzanilides.
Tetrahedron Letters.
16:2799-2800.
1975
Full text if available -
Davis MDeady LWHomfeld E. N-methyl chemical shifts in quaternized azoles, isazoles, diazoles, and their benzologs.
Journal of Heterocyclic Chemistry: international journal.
11:1011-1012.
1974
Full text if available -
Deady LWGray PMTopsom RD. Infrared Spectra of Mono- and Disubstituted Acenaphthenes.
Applied Spectroscopy.
28:552-554.
1974
Full text if available -
Broxton TJDeady LW. Mechanism of the basic methanolysis of benzanilides.
Journal of Organic Chemistry.
39:2767-2769.
1974
Full text if available -
Deady LWWillett GD. N-Methyl chemical shifts in some 2-, 3- and 4-substitutedN-methylpyridinium salts.
Magnetic Resonance in Chemistry.
6:53-54.
1974
Full text if available -
Davis MDeady LWHomfeld E. Rates of N-methylation of N-methylpyrazole, isothiazole and isoxazole and their 2,1- and 1,2-benzologues.
Australian Journal of Chemistry: an international journal for chemical science.
27:1221-1221.
1974
Full text if available -
Broxton TJDeady LWMcCormack JDKam LCToh SH. Ring bromination of aryl methyl ketones with hypobromous acid.
Organic and Biomolecular Chemistry.
1769-1769.
1974
Full text if available -
Broxton TJDeady LWWilliamson PRA. The rates of basic methanolysis of some N-Alkyl-p-nitroacetanilides and 4-(N'-Alkylacetamido)pyridines.
Australian Journal of Chemistry: an international journal for chemical science.
27:1053-1053.
1974
Full text if available -
Davis MDeady LWHomfeld E. rates of N-methylation of 2-Methybenzotriazole, 2,1,3-Benzoxadiazole, 2,1,3-Benzothia(or Selena)diazole, 1,2,5-Oxadiazole and 1,2,5-Thiadiazole.
Australian Journal of Chemistry: an international journal for chemical science.
27:1917-1917.
1974
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Deady LWKendall MTopsom RDJones RAY. The dipole moments of substituted adamantanes and the correlation of the dipole moments of aliphatic compounds with substituent constants.
Journal of the Chemical Society, Perkin Transactions 2.
416-420.
1973
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Deady LWPirzada NHTopsom RDBobbitt JM. A new synthesis of 1-Benzyl-1,2,3,4-tetrahydroisoquinoline.
Australian Journal of Chemistry: an international journal for chemical science.
26:2063-2063.
1973
Full text if available -
Deady LKatritzky ARShanks RATopsom RD. Infrared intensities as a quantitative measure of intramolecular interactions—XXI.11Part XX, see N.C. Cutress, T.B. Grindley, A.R. Katritzky, M.V. Sinnott and B.D. Topsom, submitted to J. C. S. Perkin II. Substituted benzonitriles.
Spectrochimica Acta - Part A: Molecular Spectroscopy.
29:115-121.
1973
Full text if available -
Deady LW. Rates of N-methylation of azoles with methyl iodide and dimethyl sulphate.
Australian Journal of Chemistry: an international journal for chemical science.
26:1949-1949.
1973
Full text if available -
Aumann DDeady LW. Simple method for demethylation of quaternised nitrogen heterocyclic compounds.
Journal of the Chemical Society - Series Chemical Communications.
32-32.
1973
Full text if available -
Davis MDeady LWFinch AJSmith JF. Some reactions of grignard reagents with chloroform and carbon tetrachloride in the presence of cyclohexene.
Tetrahedron.
29:349-352.
1973
Full text if available -
Deady LWPirzada NHTopsom RD. Synthesis of some tetrahydro-2- and 3-benzazepines, and of hexahydro-3-benzazocine.
Organic and Biomolecular Chemistry.
782-782.
1973
Full text if available -
Broxton TJDeady LW. The effect of DMSO on the basic methanolysis of anilides.
Tetrahedron Letters.
14:3915-3918.
1973
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Deady LWShanks RATops RD. The resonance effect of the heteroatom in pyrrole, furan, and thiophen.
Tetrahedron Letters.
14:1881-1884.
1973
Full text if available -
Broxton TJCapper GDeady LWLenko ATopsom RD. Electronic effects of bridgehead alkyl substituents: Adamantan-1-yl and bicyclo[2,2,2]octan-1-yl.
Journal of the Chemical Society, Perkin Transactions 2.
1237-1240.
1972
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DEADY LSHANKS R. A Convenient Preparation of 3-Furoic Acid.
Synthesis: journal of synthetic organic chemistry.
1972:571-571.
1972
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Deady LWGray PMTopsom RD. Electrophilic substitution in acenaphthene and related compounds. III. Acetylation of some monosubstituted acenaphthenes.
Journal of Organic Chemistry.
37:3335-3338.
1972
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Zoltewicz JADeady LW. Search for the .alpha. effect among heteroaromatic nitrogen nucleophiles.
Journal of the American Chemical Society.
94:2765-2769.
1972
Full text if available -
Zoltewicz JADeady LW. Comparison of the electronic effects of substituents bonded to annular nitrogen and carbon atoms.
Journal of Organic Chemistry.
37:501-502.
1972
Full text if available -
Zoltewicz JADeady LW. Relative rates of N-methylation of o-substituted pyridines. Steric and electronic effects.
Journal of Organic Chemistry.
37:603-607.
1972
Full text if available -
Deady LWShanks RA. A determination of the sigma zero constant for the pyridine aza group.
Australian Journal of Chemistry: an international journal for chemical science.
25:431-431.
1972
Full text if available -
Zoltewicz JADeady LW. A method of predicting the site of alkylation of heterocyclic polyazines from kinetic data on model compounds.
Tetrahedron.
28:1983-1993.
1972
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Deady LWShanks RA. Solvent dependence of pyridine aza sigma values determined from alkaline ester hydrolysis.
Australian Journal of Chemistry: an international journal for chemical science.
25:2363-2363.
1972
Full text if available -
Deady LWFoskey DJShanks RA. Transmission of substituent effects in pyridines. Part IV. Alkaline hydrolysis of methyl diazinecarboxylates.
Journal of the Chemical Society B: Physical Organic.
1962-1963.
1971
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Deady LWZoltewicz JA. Kinetic method for determining the position of alkylation of polyaza heterocycles. Substituted pyrazines.
Journal of the American Chemical Society.
93:5475-5477.
1971
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Deady LWPirzada NTopsom RD. A new synthesis of 1,2,3,4-tetrahydroisoquinolines.
Journal of the Chemical Society D: Chemical Communications.
799-799.
1971
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Deady LWPirzada NTopsom RD. The aluminium chloride-catalysed decomposition of some N-(3-bromopropyl)arylamines.
Journal of the Chemical Society C: Organic.
3719-3719.
1971
Full text if available -
Campbell ADChan EChooi SYDeady LWShanks RA. The synthesis of some substituted methyl pyridinecarboxylates. I. Methyl 6-substituted picolinates, methyl 6-substituted nicotinates, and methyl 2-substituted isonicotinates.
Australian Journal of Chemistry: an international journal for chemical science.
24:377-377.
1971
Full text if available -
Deady LWShanks RACampbell ADChooi SY. The synthesis of some substituted methyl pyridinecarboxylates. II. Methyl 4-substituted picolinates, methyl 5-substituted picolinates, and methyl 5-substituted nicotinates.
Australian Journal of Chemistry: an international journal for chemical science.
24:385-385.
1971
Full text if available -
Broxton TJDeady LWKatritzky ARLiu ATopsom RD. Infrared intensities as a quantitative measure of intramolecular interactions. XII. .pi.-Distortions in the ground states of some p-alkylbenzenes.
Journal of the American Chemical Society.
92:6845-6849.
1970
Full text if available -
Campbell ADChooi SYDeady LWShanks RA. A redetermination of the sigma constant for the pyridine aza group.
Australian Journal of Chemistry: an international journal for chemical science.
23:203-203.
1970
Full text if available -
Campbell ADChooi SYDeady LWShanks RA. Transmission of substituent effects in pyridines. Part I. Alkaline hydrolysis of some 3- and 4-substituted methyl pyridinecarboxylates.
Journal of the Chemical Society A: Inorganic, Physical, and Theoretical Chemistry.
1063-1063.
1970
Full text if available -
Campbell ADChan EChooi SYDeady LWShanks RA. Transmission of substituent effects in pyridines. Part II. Alkaline hydrolysis of some 2-substituted methyl pyridinecarboxylates.
Journal of the Chemical Society A: Inorganic, Physical, and Theoretical Chemistry.
1065-1065.
1970
Full text if available -
Campbell ADChan EChooi SYDeady LWShanks RA. Transmission of substituent effects in pyridines. Part III. A comparison of the pyridine nitrogen and aromatic nitro-groups by ester hydrolysis.
Journal of the Chemical Society A: Inorganic, Physical, and Theoretical Chemistry.
1068-1068.
1970
Full text if available -
Constantine PRDeady LWTopsom RD. Electrophilic substitution in acenaphthene and related compounds. II. Bromination and chlorination of bromo- and chloroacenaphthenes.
Journal of Organic Chemistry.
34:1113-1115.
1969
Full text if available -
Deady LWTopsom RDHutchinson REJVaughan JWright GJ. A new synthesis of N-arylazetidines.
Tetrahedron Letters.
9:1773-1776.
1968
Full text if available -
Deady LW. Preparation of oxazine derivatives and 2,4-diarylpyrroles from methyl aryl ketoximes.
Tetrahedron.
23:3505-3509.
1967
Full text if available -
Deady LWTopsom RDVaughan J. 1059. Preparation of some chromans from 1,3-diaryloxypropanes. Part II.
Journal of the Chemical Society.
5718-5718.
1965
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Deady LWTopsom RDVaughan J. Preparation of some chromans from 1,3-diaryloxy-propanes.
Journal of the Chemical Society.
2092-2094.
1963
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Deady LWLeary GJTopsom RDVaughan J. N-Arylazetidines.
Journal of Organic Chemistry.
28:511-514.
1963
Full text if available
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Buskes MJHarvey KLRichards BJKalhor RChristoff RMGardhi CKLittler DRCope EDPrinz BWeiss GEO'Brien NJCrabb BSDeady LWGilson PRAbbott BM. Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation.
Organic and Biomolecular Chemistry.
14:4617-4639.
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