selected publications
-
academic article
-
Bond STKing EJHenstridge DCTran AMoody SCYang CLiu YMellett NANath APInouye MTarling EJde Aguiar Vallim TQMeikle PJCalkin ACDrew BG. Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance.
Nature Communications.
12.
2021
Full text if available -
Abraham GMalik RYonova-Doing ESalim AWang TDanesh JButterworth ASHowson JMMInouye MDichgans M. Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
Nature Communications.
11.
2020
Full text if available -
Huang QQTang HHFTeo SMMok DRitchie SCNath APBrozynska MSalim ABakshi AHolt BJKhor CCSly PDHolt PGHolt KEInouye M. Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk.
Nature Communications.
11:1-12.
2020
Full text if available -
Cánovas RCobb JBrozynska MBowes JLi YRSmith SLHakonarson HThomson WEllis JAAbraham GMunro JEInouye M. Genomic risk scores for juvenile idiopathic arthritis and its subtypes.
Annals of the Rheumatic Diseases.
79:1572-1579.
2020
Full text if available -
Hamilton ALKamm MADe Cruz PWright EKFeng HWagner JSung JJYKirkwood CDInouye MTeo S-M. Luminal microbiota related to Crohn's disease recurrence after surgery.
Gut Microbes.
11:1713-1728.
2020
Full text if available -
Palmu JWatrous JDMercader KHavulinna ASLagerborg KASalosensaari AInouye MLarson MGRong JVasan RSLahti LAndres ACheng SJousilahti PSalomaa VJain MNiiranen TJ. Eicosanoid inflammatory mediators are robustly associated with blood pressure in the general population.
Journal of the American Heart Association.
9.
2020
Full text if available -
Wan YWick RRZobel JIngle DJInouye MHolt KE. GeneMates: an R package for detecting horizontal gene co-transfer between bacteria using gene-gene associations controlled for population structure.
BMC Genomics.
21:1-14.
2020
Full text if available -
Palmu JSalosensaari AHavulinna ASCheng SInouye MJain MSalido RASanders KBrennan CHumphrey GCSanders JGVartiainen ELaatikainen TJousilahti PSalomaa VKnight RLahti LNiiranen TJ. Association between the gut microbiota and blood pressure in a population cohort of 6953 individuals.
Journal of the American Heart Association.
9.
2020
Full text if available -
Salosensaari ALaitinen VHavulinna AMeric GCheng SPerola MValsta LAlfthan GInouye MWatrous JDLong TSalido RSanders KBrennan CHumphrey GCSanders JGJain MJousilahti PSalomaa VKnight RLahti LNiiranen T. Taxonomic Signatures of Long-Term Mortality Risk in Human Gut Microbiota
2020
Full text if available -
Tang HHFLang ATeo SMJudd LMGangnon REvans MDLee KEVrtis RHolt PGLemanske RFJackson DJHolt KEInouye MGern JE. Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk.
Journal of Allergy and Clinical Immunology.
2020
Full text if available -
Lannelongue LGrealey JInouye M. Green Algorithms: Quantifying the carbon emissions of computation..
CoRR.
abs/2007.07610.
2020
-
Weeks ALD'Antoine HAMcKinnon MSyn GBessarab DBrown NTong SYCRemenyi BSteer AGray L-AInouye MCarapetis JRBlackwell JMLassmann T. Reference exome data for Australian Aboriginal populations to support health-based research.
Scientific data.
7:1-7.
2020
Full text if available -
Tang HHFSly PDHolt PGHolt KEInouye M. Systems biology and big data in asthma and allergy: Recent discoveries and emerging challenges.
European Respiratory Journal.
55:1900844-1900844.
2020
Full text if available -
Vuckovic DBao ELAkbari PLareau CAMousas AJiang TChen M-HRaffield LMTardaguila MHuffman JERitchie SCMegy KPonstingl HPenkett CJAlbers PKWigdor EMSakaue SMoscati AManansala RLo KSQian HAkiyama MBartz TMBen-Shlomo YBeswick ABork-Jensen JBottinger EPBrody JAvan Rooij FJAChitrala KNWilson PWFChoquet HDanesh JDi Angelantonio EDimou NDing JElliott PEsko TEvans MKFelix SBFloyd JSBroer LGrarup NGuo MHGuo QGreinacher AHaessler JHansen THowson JMMHuang WJorgenson EKacprowski TKähönen MKamatani YKanai MKarthikeyan SKoskeridis FLange LALehtimäki TLinneberg ALiu YLyytikäinen L-PManichaikul AMatsuda KMohlke KLMononen NMurakami YNadkarni GNNikus KPankratz NPedersen OPreuss MPsaty BMRaitakari OTRich SSRodriguez BATRosen JDRotter JISchubert PSpracklen CNSurendran PTang HTardif J-CGhanbari MVölker UVölzke HWatkins NAWeiss SCai NKundu KWatt SBWalter KZonderman ABCho KLi YLoos RJFKnight JCGeorges MStegle OEvangelou EOkada YRoberts DJInouye MJohnson ADAuer PLAstle WJReiner APButterworth ASOuwehand WHLettre GSankaran VGSoranzo N. The polygenic and monogenic basis of blood traits and diseases.
Cell.
182:1214-1231.e11.
2020
Full text if available -
Wang MMenon RMishra SPatel APChaffin MTanneeru DDeshmukh MMathew OApte SDevanboo CSSundaram SLakshmipathy PMurugan SSharma KKRajendran KSanthosh SThachathodiyl RAhamed HBalegadde AVAlexander TSwaminathan KGupta RMullasari ASSigamani AKanchi MPeterson ASButterworth ASDanesh JDi Angelantonio ENaheed AInouye MChowdhury RVedam RLKathiresan SGupta RKhera AV. Validation of a genome-wide polygenic score for coronary artery disease in South Asians.
Journal of the American College of Cardiology.
76:703-714.
2020
Full text if available -
Grace MSFormosa MFBozaoglu KBergouignan ABrozynska MCarey ALVeiga CBSethi PDillon FBertovic DAInouye MOwen NDunstan DWKingwell BA. Acute effects of active breaks during prolonged sitting on subcutaneous adipose tissue gene expression: an ancillary analysis of a randomised controlled trial.
Scientific Reports.
9.
2019
Full text if available -
Nath APBraun ARitchie SCCarbone FRMackay LKGebhardt TInouye M. Comparative analysis reveals a role for TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells.
PLoS ONE.
14.
2019
Full text if available -
Méric GWick RRWatts SCHolt KEInouye M. Correcting index databases improves metagenomic studies.
BioXRiv.
2019
Full text if available -
Ritchie SCKettunen JBrozynska MNath APHavulinna ASMännistö SPerola MSalomaa VAla-Korpela MAbraham GWürtz PInouye M. Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.
PLoS ONE.
14:1-23.
2019
Full text if available -
Watts SCRitchie SCInouye MHolt KE. FastSpar: rapid and scalable correlation estimation for compositional data.
Bioinformatics.
35:1064-1066.
2019
Full text if available -
Abraham GMalik RYonova-Doing ESalim AWang TDanesh JButterworth ASHowson JMMInouye MDichgans M. Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
Nature Communications.
10.
2019
Full text if available -
Nath APRitchie SCGrinberg NFTang HHFHuang QQTeo SMAhola-Olli AVWürtz PHavulinna ASSantalahti KPitkänen NLehtimäki TKähönen MLyytikäinen LPRaitoharju ESeppälä ISarin APRipatti SPalotie APerola MViikari JSJalkanen SMaksimow MSalmi MWallace CRaitakari OTSalomaa VAbraham GKettunen JInouye M. Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
American Journal of Human Genetics.
105:1076-1090.
2019
Full text if available -
Lambert SAAbraham GInouye M. Towards clinical utility of polygenic risk scores.
Human Molecular Genetics.
28:R133-R142.
2019
Full text if available -
Teo SMTang HHFMok DJudd LMWatts SCPham KHolt BJKusel MSerralha MTroy NBochkov YAGrindle KLemanske RFJohnston SLGern JESly PDHolt PGHolt KEInouye M. Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.
Cell Host and Microbe.
24:341-352.
2018
Full text if available -
Kettunen JRitchie SCAnufrieva OLyytikäinen LPHernesniemi JKarhunen PJKuukasjärvi PLaurikka JKähönen MLehtimäki THavulinna ASSalomaa VMännistö SAla-Korpela MPerola MInouye MWürtz P. Biomarker Glycoprotein Acetyls is Associated with the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients.
Circulation: Genomic and Precision Medicine.
11.
2018
Full text if available -
Iglesias AIMishra AVitart VBykhovskaya YHöhn RSpringelkamp HCuellar-Partida GGharahkhani PBailey JNCWilloughby CELi XYazar SNag AKhawaja APPolašek OSiscovick DMitchell PTham YCHaines JLKearns LSHayward CShi YVan Leeuwen EMTaylor KDWang JJRochtchina EAttia JScott RHolliday EGBaird PNXie JInouye MViswanathan ASim XBonnemaijer PRotter JIMartin NGZeller TMills RAStaffieri SEJonas JBSchmidtmann IBoutin TKang JHLucas SEMWong TYBeutel MEWilson JFAllingham RRBrilliant MHBudenz DLChristen WGFingert JFriedman DSGaasterland DGaasterland THauser MAKraft PLee RKLichter PRLiu YLoomis SJMoroi SEPericak-Vance MARealini ARichards JESchuman JSScott WKSingh KSit AJVollrath DWeinreb RNWollstein GZack DJZhang KDonnelly PBarroso IBlackwell JMBramon EBrown MACasas JPCorvin ADeloukas PDuncanson AJankowski JMarkus HSMathew CGPalmer CNAPlomin RRautanen ASawcer SJTrembath RCWood NWSpencer CCABand GBellenguez CFreeman CHellenthal GGiannoulatou EPirinen M. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Nature Communications.
9.
2018
Full text if available -
Holt KEMcAdam PThai PVKThuong NTTHa DTMLan NNLan NHNhu NTQHai HTHa VTNThwaites GEdwards DJNath APPham KAscher DBFarrar JKhor CCTeo YYInouye MCaws MDunstan SJ. Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam.
Nature Genetics.
50:849-856.
2018
Full text if available -
Inouye MAbraham GNelson CPWood AMSweeting MJDudbridge FLai FYKaptoge SBrozynska MWang TYe SWebb TRRutter MKTzoulaki IPatel RSLoos RJFKeavney BHemingway HThompson JWatkins HDeloukas PDi Angelantonio EButterworth ASDanesh JSamani NJ. Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Journal of the American College of Cardiology.
72:1883-1893.
2018
Full text if available -
Bhalala OGNath APRyten MWeale MEHardy JD'Sa KRamasamy ATrabzuni DGuelfi SBotia JAVandrovcova JSmith CWalker RInouye MSibley CR. Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.
PLoS Genetics.
14:1-25.
2018
Full text if available -
Huang QQRitchie SCBrozynska MInouye M. Power, false discovery rate and Winner's Curse in eQTL studies.
Nucleic Acids Research.
46:1-12.
2018
Full text if available -
Tang HHFTeo SMBelgrave DCMEvans MDJackson DJBrozynska MKusel MMHJohnston SLGern JELemanske RFSimpson ACustovic ASly PDHolt PGHolt KEInouye M. Trajectories of childhood immune development and respiratory health relevant to asthma and allergy.
eLife.
7:1-31.
2018
Full text if available -
Renz HHolt PGInouye MLogan ACPrescott SLSly PD. An exposome perspective: Early-life events and immune development in a changing world.
Journal of Allergy and Clinical Immunology.
140:24-40.
2017
Full text if available -
Nath APRitchie SCByars SGFearnley LGHavulinna ASJoensuu AKangas AJSoininen PWennerström AMilani LMetspalu AMännistö SWürtz PKettunen JRaitoharju EKähönen MJuonala MPalotie AAla-Korpela MRipatti SLehtimäki TAbraham GRaitakari OSalomaa VPerola MInouye M. An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.
Genome Biology: biology for the post-genomic era.
18.
2017
Full text if available -
Marques FZPrestes PRByars SGRitchie SCWürtz PPatel SKBooth SARana IMinoda YBerzins SPCurl CLBell JRWai BSrivastava PMKangas AJSoininen PRuohonen SKähönen MLehtimäki TRaitoharju EHavulinna APerola MRaitakari OSalomaa VAla‐Korpela MKettunen JMcGlynn MKelly JWlodek MELewandowski PADelbridge LMBurrell LMInouye MHarrap SBCharchar FJ. Experimental and human evidence for Lipocalin‐2 (Neutrophil Gelatinase‐Associated Lipocalin [NGAL]) in the development of cardiac hypertrophy and heart failure.
Journal of the American Heart Association.
6.
2017
Full text if available -
Byars SGHuang QQGray L-ABakshi ARipatti SAbraham GStearns SCInouye M. Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
PLoS Genetics.
13.
2017
Full text if available -
Gray L-AD’Antoine HATong SYCMcKinnon MBessarab DBrown NReményi BSteer ASyn GBlackwell JMInouye MCarapetis JR. Genome-wide analysis of genetic risk factors for rheumatic heart disease in Aboriginal Australians provides support for pathogenic molecular mimicry.
Journal of Infectious Diseases.
216:1460-1470.
2017
Full text if available -
Goudey BAbraham GKikianty EWang QRawlinson DShi FHaviv IStern LKowalczyk AInouye M. Interactions within the MHC contribute to the genetic architecture of celiac disease.
PLoS ONE.
12.
2017
Full text if available -
Wright EKKamm MAWagner JTeo S-MCruz PDHamilton ALRitchie KJInouye MKirkwood CD. Microbial Factors Associated with Postoperative Crohn’s Disease Recurrence.
Journal of Crohn's and Colitis.
11:191-203.
2017
Full text if available -
Hollams EMTeo SMKusel MHolt BJHolt KEInouye MDe Klerk NHZhang GSly PDHart PHHolt PG. Vitamin D over the first decade and susceptibility to childhood allergy and asthma.
Journal of Allergy and Clinical Immunology.
139:472-481.
2017
Full text if available -
Ritchie SCWatts SFearnley LGHolt KEAbraham GInouye M. A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets.
Cell Systems.
3:71-82.
2016
Full text if available -
Abraham GHavulinna ASBhalala OGByars SGDe Livera AMYetukuri LTikkanen EPerola MSchunkert HSijbrands EJPalotie ASamani NJSalomaa VRipatti SInouye M. Genomic prediction of coronary heart disease.
European Heart Journal.
37:3267-3278.
2016
Full text if available -
Holt KEIngle DJLevine MMKuzevski AValcanis MRobins-Browne RMTauschek MInouye MStinear T. In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.
Microbial Genomics.
2.
2016
Full text if available -
Shu LZhao YKurt ZByars SGTukiainen TKettunen JOrozco LDPellegrini MLusis AJRipatti SZhang BInouye MMäkinen V-PYang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.
BMC Genomics.
17.
2016
Full text if available -
Fearnley LGInouye M. Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks.
International Journal of Epidemiology.
45:1319-1328.
2016
Full text if available -
Abraham GRohmer ATye-Din JAInouye M. Genomic prediction of celiac disease targeting HLA-positive individuals.
Genome Medicine: medicine in the post-genomic era.
7.
2015
Full text if available -
Abraham GInouye M. Genomic risk prediction of complex human disease and its clinical application.
Current Opinion in Genetics and Development.
33:10-16.
2015
Full text if available -
Goudey BAbedini MHopper JLInouye MMakalic ESchmidt DFWagner JZhou ZZobel JReumann M. High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies.
Health Information Science and Systems.
3.
2015
Full text if available -
Martin WJSteer ACSmeesters PRKeeble JInouye MCarapetis JWicks IP. Post-infectious group A streptococcal autoimmune syndromes and the heart.
Autoimmunity Reviews.
14:710-725.
2015
Full text if available -
Wright EKKamm MATeo SMInouye MWagner JKirkwood CD. Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: A systematic review.
Inflammatory Bowel Diseases.
21:1219-1228.
2015
Full text if available -
Wang ZWan YQiu CQuiñones-Parra SZhu ZLoh LTian DRen YHu YZhang XThomas PGInouye MDoherty PCKedzierska KXu J. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells.
Nature Communications.
6.
2015
Full text if available -
Ritchie SCWürtz PNath APAbraham GHavulinna ASFearnley LGSarin A-PKangas AJSoininen PAalto KSeppälä IRaitoharju ESalmi MMaksimow MMännistö SKähönen MJuonala MRipatti SLehtimäki TJalkanen SPerola MRaitakari OSalomaa VAla-Korpela MKettunen JInouye M. The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection.
Cell Systems.
1:293-301.
2015
Full text if available -
Teo SMMok DPham KKusel MSerralha MTroy NHolt BJHales BJWalker MLHollams EBochkov YAGrindle KJohnston SLGern JESly PDHolt PGHolt KEInouye M. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.
Cell Host and Microbe.
17:704-715.
2015
Full text if available -
Shi WLiao YWillis SNTaubenheim NInouye MTarlinton DMSmyth GKHodgkin PDNutt SLCorcoran LM. Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.
Nature Immunology.
16:663-673.
2015
Full text if available -
Inouye MAbraham G. Correction: Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning.
PLoS Genetics.
10:e1004374-e1004374.
2014
Full text if available -
Abraham GTye-Din JABhalala OGKowalczyk AZobel JInouye M. Accurate and robust genomic prediction of Celiac disease using statistical learning.
PLoS Genetics.
10.
2014
Full text if available -
Lim ETWürtz PHavulinna ASPalta PTukiainen TRehnström KEsko TMägi RInouye MLappalainen TChan YSalem RMLek MFlannick JSim XManning ALadenvall CBumpstead SHämäläinen EAalto KMaksimow MSalmi MBlankenberg SArdissino DShah SHorne BMcPherson RHovingh GKReilly MPWatkins HGoel AFarrall MGirelli DReiner APStitziel NOKathiresan SGabriel SBarrett JCLehtimäki TLaakso MGroop LKaprio JPerola MMcCarthy MIBoehnke MAltshuler DMLindgren CMHirschhorn JNMetspalu AFreimer NBZeller TJalkanen SKoskinen SRaitakari ODurbin RMacArthur DGSalomaa VRipatti SDaly MJPalotie A. Distribution and medical impact of loss-of-function variants in the Finnish founder population.
PLoS Genetics.
10.
2014
Full text if available -
Walker MLHolt KEAnderson GPTeo SMSly PDHolt PGInouye M. Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy.
Frontiers in Immunology.
5.
2014
Full text if available -
Abraham GInouye M. Fast principal component analysis of large-scale genome-wide data.
PLoS ONE.
9.
2014
Full text if available -
Hysi PGCheng C-YSpringelkamp HMacgregor SBailey JNCWojciechowski RVitart VNag AHewitt AWHöhn RVenturini CMirshahi ARamdas WDThorleifsson GVithana EKhor C-CStefansson ABLiao JHaines JLAmin NWang YXWild PSOzel ABLi JZFleck BWZeller TStaffieri SETeo Y-YCuellar-Partida GLuo XAllingham RRRichards JESenft AKarssen LCZheng YBellenguez CXu LIglesias AIWilson JFKang JHvan Leeuwen EMJonsson VThorsteinsdottir UDespriet DDGEnnis SMoroi SEMartin NGJansonius NMYazar STai E-SAmouyel PKirwan Jvan Koolwijk LMEHauser MAJonasson FLeo PLoomis SJFogarty RRivadeneira FKearns LLackner KJde Jong PTVMSimpson CLPennell CEOostra BAUitterlinden AGSaw S-MLotery AJBailey-Wilson JEHofman AVingerling JRMaubaret CPfeiffer NWolfs RCWLemij HGYoung TLPasquale LRDelcourt CSpector TDKlaver CCWSmall KSBurdon KPStefansson KWong T-YPaul MWang JJRochtchina EAttia JScott RHolliday EWong TYBaird PMXie JInouye MViswanath ASim XAllingham RRBrillian MBudenz DCooke Bailey JNChristen WGFingert JFriedman DSGaasterland DGaasterland THaines JLHauser MAKang JHKraft PLee RKLichter PALiu YLoomis SJMoroi SEPasquale LRPericak-Vance MARealini ARichards JESchuman JSScott WKSingh KSit AJVollrath DWeinreb RNWiggs JLWollstein GZack DJZhang KDonnelly PBarroso IBlackwell JMBramon EBrown MACasas JPCorvin ADeloukas PDuncanson AJankowski JMarkus HSMathew CGPalmer CNAPlomin RRautanen ASawcer SJTrembath RCViswanathan ACWood NWSpencer CCABand GBellenguez CFreeman CHellenthal GGiannoulatou EPirinen MPearson RStrange ASu ZVukcevic DDonnelly PLangford CHunt SEEdkins SGwilliam RBlackburn HBumpstead SJDronov SGillman MGray EHammond NJayakumar AMcCann OTLiddle JPotter SCRavindrarajah RRicketts MWaller MWeston PWidaa SWhittaker PBarroso IDeloukas PViswanathan AMackey DACraig JEWiggs JLvan Duijn CMHammond CJAung T. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
Nature Genetics.
46:1126-1130.
2014
Full text if available -
Springelkamp HHöhn RMishra AHysi PGKhor C-CLoomis SJBailey JNCGibson JThorleifsson GJanssen SFLuo XRamdas WDVithana ENongpiur MEMontgomery GWXu LMountain JEGharahkhani PLu YAmin NKarssen LCSim K-Svan Leeuwen EMIglesias AIVerhoeven VJMHauser MALoon S-CDespriet DDGNag AVenturini CSanfilippo PGSchillert AKang JHLanders JJonasson FCree AJvan Koolwijk LMERivadeneira FSouzeau EJonsson VMenon GMitchell PWang JJRochtchina EAttia JScott RHolliday EGWong T-YBaird PNXie JInouye MViswanathan ASim XWeinreb RNde Jong PTVMOostra BAUitterlinden AGHofman AEnnis SThorsteinsdottir UBurdon KPAllingham RRBrilliant MHBudenz DLCooke Bailey JNChristen WGFingert JFriedman DSGaasterland DGaasterland THaines JLHauser MAKang JHKraft PLee RKLichter PRLiu YLoomis SJMoroi SEPasquale LRPericak-Vance MARealini ARichards JESchuman JSScott WKSingh KSit AJVollrath DWeinreb RNWiggs JLWollstein GZack DJZhang KDonnelly PBarroso IBlackwell JMBramon EBrown MACasas JPCorvin ADeloukas PDuncanson AJankowski JMarkus HSMathew CGPalmer CNAPlomin RRautanen ASawcer SJTrembath RCViswanathan ACWood NWSpencer CCABand GBellenguez CFreeman CHellenthal GGiannoulatou EPirinen MPearson RStrange ASu ZVukcevic DLangford CHunt SEEdkins SGwilliam RBlackburn HBumpstead SJDronov SGillman MGray EHammond NJayakumar AMcCann OTLiddle JPotter SCRavindrarajah RRicketts MWaller MWeston PWidaa SWhittaker PSpector TDMirshahi ASaw S-MVingerling JRTeo Y-YHaines JLWolfs RCWLemij HGTai E-SJansonius NMJonas JBCheng C-YAung TViswanathan ACKlaver CCWCraig JEMacgregor SMackey DALotery AJStefansson KBergen AABYoung TLPfeiffer NWong T-YHewitt AWvan Duijn CMHammond CJ. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.
Nature Communications.
5.
2014
Full text if available -
Inouye MDashnow HRaven L-ASchultz MBPope BJTomita TZobel JHolt KE. SRST2: Rapid genomic surveillance for public health and hospital microbiology labs.
Genome Medicine: medicine in the post-genomic era.
6.
2014
Full text if available -
Carotta SWillis SNHasbold JInouye MPang SHMEmslie DLight AChopin MShi WWang HMorse HCTarlinton DMCorcoran LMHodgkin PDNutt SL. The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Journal of Experimental Medicine.
211:2169-2181.
2014
Full text if available -
Abraham GBhalala OGde Bakker PIWRipatti SInouye M. Towards a molecular systems model of coronary artery disease.
Current Cardiology Reports.
16.
2014
Full text if available -
Goudey BRawlinson DWang QShi FFerra HCampbell RMStern LInouye MTOng CSKowalczyk A. GWIS - model-free, fast and exhaustive search for epistatic interactions in case-control GWAS.
BMC Genomics.
14.
2013
Full text if available -
Sim XJensen RAIkram MKCotch MFLi XMacGregor SXie JSmith AVBoerwinkle EMitchell PKlein RKlein BEKGlazer NLLumley TMcKnight BPsaty BMde Jong PTVMHofman ARivadeneira FUitterlinden AGvan Duijn CMAspelund TEiriksdottir GHarris TBJonasson FLauner LJAttia JBaird PNHarrap SHolliday EGInouye MRochtchina EScott RJViswanathan ALi GSmith NLWiggins KLKuo JZTaylor KDHewitt AWMartin NGMontgomery GWSun CYoung TLMackey DAvan Zuydam NRDoney ASFPalmer CNAMorris ADRotter JITai ESGudnason VVingerling JRSiscovick DSWang JJWong TY. Genetic loci for retinal arteriolar microcirculation.
PLoS ONE.
8.
2013
Full text if available -
Holliday EGSmith AVCornes BKBuitendijk GHSJensen RASim XAspelund TAung TBaird PNBoerwinkle ECheng CYvan Duijn CMEiriksdottir GGudnason VHarris THewitt AWInouye MJonasson FKlein BEKLauner LLi XLiew GLumley TMcElduff PMcKnight BMitchell PPsaty BMRochtchina ERotter JIScott RJTay WTaylor KTeo YYUitterlinden AGViswanathan AXie SVingerling JRKlaver CCWTai ESSiscovick DKlein RCotch MFWong TYAttia JWang JJ. Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis.
PLoS ONE.
8.
2013
Full text if available -
Stambolian DWojciechowski ROexle KPirastu MLi XRaffel LJCotch MFChew EYKlein BKlein RWong TYSimpson CLKlaver CCWvan Duijn CMVerhoeven VJMBaird PNVitart VPaterson ADMitchell PSaw SMFossarello MKazmierkiewicz KMurgia FPortas LSchache MRichardson AXie JWang JJRochtchina EViswanathan ACHayward CWright AFPolašek OCampbell HRudan IOostra BAUitterlinden AGHofman ARivadeneira FAmin NKarssen LCVingerling JRHosseini SMDöring ABettecken TVatavuk ZGieger CWichmann H-EWilson JFFleck BFoster PJTopouzis FMcGuffin PSim XInouye MHolliday EGAttia JScott RJRotter JIMeitinger TBailey-Wilson JE. Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.
Human Molecular Genetics.
22:2754-2764.
2013
Full text if available -
Abraham GKowalczyk AZobel JInouye M. Performance and robustness of penalized and unpenalized methods for genetic prediction of complex human disease.
Genetic Epidemiology.
37:184-195.
2013
Full text if available -
Mackay LKRahimpour AMa JZCollins NStock ATHafon M-LVega-Ramos JLauzurica PMueller SNStefanovic TTscharke DCHeath WRInouye MCarbone FRGebhardt T. The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin.
Nature Immunology.
14:1294-1301.
2013
Full text if available -
Inouye MEyre SBowes JDiogo DLee ABarton AMartin PZhernakova AStahl EViatte SMcAllister KAmos CIPadyukov LToes REMHuizinga TWJWijmenga CTrynka GFranke LWestra H-JAlfredsson LHu XSandor Cde Bakker PIWDavila SKhor CCHeng KKAndrews REdkins SHunt SELangford CSymmons DConcannon POnengut-Gumuscu SRich SSDeloukas PGonzalez-Gay MARodriguez-Rodriguez LÄrlsetig LMartin JRantapää-Dahlqvist SPlenge RMRaychaudhuri SKlareskog LGregersen PKWorthington J. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
Nature Genetics.
44:1336-1340.
2012
Full text if available -
Abraham GKowalczyk AZobel JInouye M. SparSNP: Fast and memory-efficient analysis of all SNPs for phenotype prediction.
BMC Bioinformatics.
13.
2012
Full text if available -
Inouye MRipatti SKettunen JLyytikäinen L-POksala NLaurila P-PKangas AJSoininen PSavolainen MJViikari JKähönen MPerola MSalomaa VRaitakari OLehtimäki TTaskinen M-RJärvelin M-RAla-Korpela MPalotie Ade Bakker PIW. Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis.
PLoS Genetics.
8:e1002907-e1002907.
2012
Full text if available -
Kettunen JTukiainen TSarin A-POrtega-Alonso ATikkanen ELyytikäinen L-PKangas AJSoininen PWürtz PSilander KDick DMRose RJSavolainen MJViikari JKähönen MLehtimäki TPietiläinen KHInouye MMcCarthy MIJula AEriksson JRaitakari OTSalomaa VKaprio JJärvelin M-RPeltonen LPerola MFreimer NBAla-Korpela MPalotie ARipatti S. Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
Nature Genetics.
44:269-276.
2012
Full text if available -
Inouye MConway TCZobel JHolt KE. Short read sequence typing (SRST): multi-locus sequence types from short reads.
BMC Genomics.
13:338-338.
2012
Full text if available -
Ala-Korpela MKangas AJInouye M. Genome-wide association studies and systems biology: together at last.
Trends in Genetics.
27:493-498.
2011
Full text if available -
Church PCGoscinski AHolt KInouye MGhoting AMakarychev KReumann M. Design of multiple sequence alignment algorithms on parallel, distributed memory supercomputers.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
2011:924-927.
2011
Full text if available -
Waterworth DMRicketts SLSong KChen LZhao JHRipatti SAulchenko YSZhang WYuan XLim NLuan JAshford SWheeler EYoung EHHadley DThompson JRBraund PSJohnson TStruchalin MSurakka ILuben RKhaw K-TRodwell SALoos RJFBoekholdt SMInouye MDeloukas PElliott PSchlessinger DSanna SScuteri AJackson AMohlke KLTuomilehto JRoberts RStewart AKesäniemi YAMahley RWGrundy SMMcArdle WCardon LWaeber GVollenweider PChambers JCBoehnke MAbecasis GRSalomaa VJärvelin M-RRuokonen ABarroso IEpstein SEHakonarson HHRader DJReilly MPWitteman JCMHall ASSamani NJStrachan DPBarter Pvan Duijn CMKooner JSPeltonen LWareham NJMcPherson RMooser VSandhu MS. Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease.
Arteriosclerosis, Thrombosis and Vascular Biology.
30:2264-2276.
2010
Full text if available -
Surakka IKristiansson KAnttila VInouye MBarnes CMoutsianas LSalomaa VDaly MPalotie APeltonen LRipatti S. Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging.
Genome Research.
20:1344-1351.
2010
Full text if available -
Anttila VStefansson HKallela MTodt UTerwindt GMCalafato MSNyholt DRDimas ASFreilinger TMüller-Myhsok BArtto VInouye MAlakurtti KKaunisto MAHämäläinen EDe Vries BStam AHWeller CMHeinze AHeinze-Kuhn KGoebel IBorck GGöbel HSteinberg SWolf CBjörnsson AGudmundsson GKirchmann MHauge AWerge TSchoenen JEriksson JGHagen KStovner LWichmann HEMeitinger TAlexander MMoebus SSchreiber SAulchenko YSBreteler MMBUitterlinden AGHofman AVan Duijn CMTikka-Kleemola PVepsäläinen SLucae STozzi FMuglia PBarrett JKaprio JFärkkilä MPeltonen LStefansson KZwart JAFerrari MDOlesen JDaly MWessman MVan Den Maagdenberg AMJMDichgans MKubisch CDermitzakis ETFrants RRPalotie A. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.
Nature Genetics.
42:869-873.
2010
Full text if available -
Inouye MSilander KHamalainen ESalomaa VHarald KJousilahti PMännistö SEriksson JGSaarela JRipatti SPerola Mvan Ommen G-JBTaskinen M-RPalotie ADermitzakis ETPeltonen L. An Immune Response Network Associated with Blood Lipid Levels.
PLoS Genetics.
6:e1001113-e1001113.
2010
Full text if available -
Altshuler DMGibbs RAPeltonen LSchaffner SFYu FDermitzakis EBonnen PEDe Bakker PIWDeloukas PGabriel SBGwilliam RHunt SInouye MJia XAarno PalotieParkin MWhittaker PChang KHawes ALewis LRRen YWheeler DMuzny DMBarnes CDarvishi KHurles MKorn JMKristiansson KLee CMcCarroll SANemesh JKeinan AMontgomery SBSamuela PollackPrice ALSoranzo NGonzaga-Jauregui CAnttila VBrodeur WDaly MJLeslie SMcVean GMoutsianas LNguyen HZhang QGhori MJRMcGinnis RMcLaren WPollack STakeuchi FGrossman SRShlyakhter IHostetter EBSabeti PCAdebamowo CAFoster MWGordon DRLicinio JManca MCMarshall PAMatsuda INgare DWang VOReddy DRotimi CNRoyal CDSharp RRZeng CBrooks DBMcEwen JE. Integrating common and rare genetic variation in diverse human populations.
Nature.
467:52-58.
2010
Full text if available -
Saleheen DSoranzo NRasheed AScharnagl HGwilliam RAlexander MInouye MZaidi MPotter SHaycock PBumpstead SKaptoge SDi Angelantonio ESarwar NHunt SESheikh NShah NSamuel MHaider SRMurtaza MThompson AGobin RButterworth AAhmad UHakeem AZaman KSKundi AYaqoob ZCheema LAQamar NFaruqui AMallick NHAzhar MSamad AIshaq MRasheed SZJooma RNiazi JHGardezi ARMemon NAGhaffar ARehman F-UHoffmann MMRenner WKleber MEGrammer TBStephens JAttwood AKoch KHussain MKumar KSaleem AKumar KDaood MSGul AAAbbas SZafar JShahid FBhatti SMAli SSMuhammad FSagoo GBray SMcGinnis RDudbridge FWinkelmann BRBöehm BThompson SOuwehand WMärz WFrossard PDanesh JDeloukas P. Genetic Determinants of Major Blood Lipids in Pakistanis Compared With Europeans.
Circulation: Cardiovascular Genetics.
3:348-357.
2010
Full text if available -
McGinnis REDeloukas PMcLaren WMInouye M. Visualizing Chromosome Mosaicism and Detecting Ethnic Outliers by the Method of "Rare" Heterozygotes and Homozygotes (RHH).
Human Molecular Genetics.
19:2539-2553.
2010
Full text if available -
Inouye MKettunen JSoininen PSilander KRipatti SKumpula LSHämäläinen EJousilahti PKangas AJMännistö SSavolainen MJJula ALeiviskä JPalotie ASalomaa VPerola MAla‐Korpela MPeltonen L. Metabonomic, transcriptomic, and genomic variation of a population cohort.
Molecular Systems Biology.
6:441-441.
2010
Full text if available -
Zhai Gvan Meurs JBJLivshits GMeulenbelt IValdes AMSoranzo NHart DZhang FKato BSRichards JBWilliams FMKInouye MKloppenburg MDeloukas PSlagboom EUitterlinden ASpector TD. A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.
Journal of Medical Genetics.
46:614-616.
2009
Full text if available -
Jallow MTeo YYSmall KSRockett KADeloukas PClark TGKivinen KBojang KAConway DJPinder MSirugo GSisay-Joof FUsen SAuburn SBumpstead SJCampino SCoffey ADunham AFry AEGreen AGwilliam RHunt SEInouye MJeffreys AEMendy APalotie APotter SRagoussis JRogers JRowlands KSomaskantharajah EWhittaker PWidden CDonnelly PHowie BMarchini JMorris ASanJoaquin MAchidi EAAgbenyega TAllen AAmodu OCorran PDjimde ADolo ADoumbo OKDrakeley CDunstan SEvans JFarrar JFernando DHien TTHorstmann RDIbrahim MKarunaweera NKokwaro GKoram KALemnge MMakani JMarsh KMichon PModiano DMolyneux MEMueller IParker MPeshu NPlowe CVPuijalon OReeder JReyburn HRiley EMSakuntabhai ASinghasivanon PSirima STall ATaylor TEThera MTroye-Blomberg MWilliams TNWilson MKwiatkowski DP. Genome-wide and fine-resolution association analysis of malaria in West Africa.
Nature Genetics.
41:657-665.
2009
Full text if available -
Inouye MNewton-Cheh CJohnson TGateva VTobin MDBochud MCoin LNajjar SSZhao JHHeath SCEyheramendy SPapadakis KVoight BFScott LJZhang FFarrall MTanaka TWallace CChambers JCKhaw K-TNilsson Pvan der Harst PPolidoro SGrobbee DEOnland-Moret NCBots MLWain LVElliott KSTeumer ALuan JLucas GKuusisto JBurton PRHadley DMcArdle WLBrown MDominiczak ANewhouse SJSamani NJWebster JZeggini EBeckmann JSBergmann SLim NSong KVollenweider PWaeber GWaterworth DMYuan XGroop LOrho-Melander MAllione ADi Gregorio AGuarrera SPanico SRicceri FRomanazzi VSacerdote CVineis PBarroso ISandhu MSLuben RNCrawford GJJousilahti PPerola MBoehnke MBonnycastle LLCollins FSJackson AUMohlke KLStringham HMValle TTWiller CJBergman RNMorken MADöring AGieger CIllig TMeitinger TOrg EPfeufer AWichmann HEKathiresan SMarrugat JO'Donnell CJSchwartz SMSiscovick DSSubirana IFreimer NBHartikainen A-LMcCarthy MIO'Reilly PFPeltonen LPouta Ade Jong PESnieder Hvan Gilst WHClarke RGoel AHamsten APeden JFSeedorf USyvänen A-CTognoni GLakatta EGSanna SScheet PSchlessinger DScuteri ADörr MErnst FFelix SBHomuth GLorbeer RReffelmann TRettig RVölker UGalan PGut IGHercberg SLathrop GMZelenika DDeloukas PSoranzo NWilliams FMZhai GSalomaa VLaakso MElosua RForouhi NGVölzke HUiterwaal CSvan der Schouw YTNumans MEMatullo GNavis GBerglund GBingham SAKooner JSConnell JMBandinelli SFerrucci LWatkins HSpector TDTuomilehto JAltshuler DStrachan DPLaan MMeneton PWareham NJUda MJarvelin M-RMooser VMelander OLoos RJFElliott PAbecasis GRCaulfield MMunroe PB. Genome-wide association study identifies eight loci associated with blood pressure.
Nature Genetics.
41:666-676.
2009
Full text if available -
Soranzo NRivadeneira FChinappen-Horsley UMalkina IRichards JBHammond NStolk LNica AInouye MHofman AStephens JWheeler EArp PGwilliam RJhamai PMPotter SChaney AGhori MJRRavindrarajah RErmakov SEstrada KPols HAPWilliams FMMcArdle WLvan Meurs JBLoos RJFDermitzakis ETAhmadi KRHart DJOuwehand WHWareham NJBarroso ISandhu MSStrachan DPLivshits GSpector TDUitterlinden AGDeloukas P. Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size.
PLoS Genetics.
5:e1000445-e1000445.
2009
Full text if available -
Prokopenko ILangenberg CFlorez JCSaxena RSoranzo NThorleifsson GLoos RJFManning AKJackson AUAulchenko YPotter SCErdos MRSanna SHottenga J-JWheeler EKaakinen MLyssenko VChen W-MAhmadi KBeckmann JSBergman RNBochud MBonnycastle LLBuchanan TACao ACervino ACoin LCollins FSCrisponi Lde Geus EJCDehghan ADeloukas PDoney ASFElliott PFreimer NGateva VHerder CHofman AHughes TEHunt SIllig TInouye MIsomaa BJohnson TKong AKrestyaninova MKuusisto JLaakso MLim NLindblad ULindgren CMMcCann OTMohlke KLMorris ADNaitza SOrrù MPalmer CNAPouta ARandall JRathmann WSaramies JScheet PScott LJScuteri ASharp SSijbrands ESmit JHSong KSteinthorsdottir VStringham HMTuomi TTuomilehto JUitterlinden AGVoight BFWaterworth DWichmann H-EWillemsen GWitteman JCMYuan XZhao JHZeggini ESchlessinger DSandhu MBoomsma DIUda MSpector TDPenninx BWJHAltshuler DVollenweider PJarvelin MRLakatta EWaeber GFox CSPeltonen LGroop LCMooser VCupples LAThorsteinsdottir UBoehnke MBarroso IVan Duijn CDupuis JWatanabe RMStefansson KMcCarthy MIWareham NJMeigs JBAbecasis GR. Variants in MTNR1B influence fasting glucose levels.
Nature Genetics.
41:77-81.
2009
Full text if available -
Wang JWang WLi RLi YTian GGoodman LFan WZhang JLi JZhang JGuo YFeng BLi HLu YFang XLiang HDu ZLi DZhao YHu YYang ZZheng HHellmann IInouye MPool JYi XZhao JDuan JZhou YQin JMa LLi GYang ZZhang GYang BYu CLiang FLi WLi SLi DNi PRuan JLi QZhu HLiu DLu ZLi NGuo GZhang JYe JFang LHao QChen QLiang YSu Ysan APing CYang SChen FLi LZhou KZheng HRen YYang LGao YYang GLi ZFeng XKristiansen KWong GK-SNielsen RDurbin RBolund LZhang XLi SYang HWang J. The diploid genome sequence of an Asian individual.
Nature.
456:60-65.
2008
Full text if available -
Loos RJFLindgren CMLi SWheeler EZhao JHProkopenko IInouye MFreathy RMAttwood APBeckmann JSBerndt SIBergmann SBennett AJBingham SABochud MBrown MCauchi SConnell JMCooper CSmith GDDay IDina CDe SDermitzakis ETDoney ASFElliott KSElliott PEvans DMSadaf Farooqi IFroguel PGhori JGroves CJGwilliam RHadley DHall ASHattersley ATHebebrand JHeid IMHerrera BHinney AHunt SEJarvelin M-RJohnson TJolley JDMKarpe FKeniry AKhaw K-TLuben RNMangino MMarchini JMcArdle WLMcGinnis RMeyre DMunroe PBMorris ADNess ARNeville MJNica ACOng KKO'Rahilly SOwen KRPalmer CNAPapadakis KPotter SPouta AQi LRandall JCRayner NWRing SMSandhu MSScherag ASims MASong KSoranzo NSpeliotes EKSyddall HETeichmann SATimpson NJTobias JHUda MGanz Vogel CIWallace CWaterworth DMWeedon MNWiller CJWraight VLYuan XZeggini EHirschhorn JNStrachan DPOuwehand WHCaulfield MJSamani NJFrayling TMVollenweider PWaeber GMooser VDeloukas PMcCarthy MIWareham NJBarroso I. Common variants near MC4R are associated with fat mass, weight and risk of obesity.
Nature Genetics.
40:768-775.
2008
Full text if available -
Fisher SATremelling MAnderson CAGwilliam RBumpstead SPrescott NJNimmo ERMassey DBerzuini CJohnson CBarrett JCCummings FRDrummond HLees CWOnnie CMHanson CEBlaszczyk KInouye MEwels PRavindrarajah RKeniry AHunt SCarter MWatkins NOuwehand WLewis CMCardon LLobo AForbes ASanderson JJewell DPMansfield JCDeloukas PMathew CGParkes MSatsangi J. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
Nature Genetics.
40:710-712.
2008
Full text if available -
Richards JBRivadeneira FInouye MPastinen TMSoranzo NWilson SGAndrew TFalchi MGwilliam RAhmadi KRValdes AMArp PWhittaker PVerlaan DJJhamai MKumanduri VMoorhouse Mvan Meurs JBHofman APols HAPHart DZhai GKato BSMullin BHZhang FDeloukas PUitterlinden AGSpector TD. Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.
Lancet.
371:1505-1512.
2008
Full text if available -
Inouye MWeedon MNLango HLindgren CMWallace CEvans DMMangino MFreathy RMPerry JRBStevens SHall ASSamani NJShields BProkopenko IFarrall MDominiczak AJohnson TBergmann SBeckmann JSVollenweider PWaterworth DMMooser VPalmer CNAMorris ADOuwehand WHCaulfield MMunroe PBHattersley ATMcCarthy MIFrayling TM. Genome-wide association analysis identifies 20 loci that influence adult height.
Nature Genetics.
40:575-583.
2008
Full text if available -
Teo YYInouye MSmall KSFry AEPotter SCDunstan SJSeielstad MBarroso IWareham NJRockett KAKwiatkowski DPDeloukas P. Whole genome–amplified DNA: insights and imputation.
Nature Methods.
5:279-280.
2008
Full text if available -
Sandhu MSWaterworth DMDebenham SLWheeler EPapadakis KZhao JHSong KYuan XJohnson TAshford SInouye MLuben RSims MHadley DMcArdle WBarter PKesäniemi YAMahley RWMcPherson RGrundy SMBingham SAKhaw K-TLoos RJFWaeber GBarroso IStrachan DPDeloukas PVollenweider PWareham NJMooser V. LDL-cholesterol concentrations: a genome-wide association study.
Lancet.
371:483-491.
2008
Full text if available -
Inouye MNejentsev SHowson JMMWalker NMSzeszko JField SFStevens HEReynolds PHardy MKing EMasters JHulme JMaier LMSmyth DBailey RCooper JDRibas GCampbell RDClayton DGTodd JA. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.
Nature.
450:887-892.
2007
Full text if available -
Inouye MBurton PRClayton DGCardon LRCraddock NDeloukas PDuncanson AKwiatkowski DPMcCarthy MIOuwehand WHSamani NJTodd JADonnelly PBarrett JCDavison DEaston DEvans DMLeung HTMarchini JLMorris APSpencer CCATobin MDAttwood APBoorman JPCant BEverson UHussey JMJolley JDKnight ASKoch KMeech ENutland SProwse CVStevens HETaylor NCWalters GRWalker NMWatkins NAWinzer TJones RWMcArdle WLRing SMStrachan DPPembrey MBreen GClair DSCaesar SGordon-Smith KJones LFraser CGreen EKGrozeva DHamshere MLHolmans PAJones IRKirov GMoskivina VNikolov IO'Donovan MCOwen MJCollier DAElkin AFarmer AWilliamson RMcGuffin PYoung AHFerrier INBall SGBalmforth AJBarrett JHBishop TDIles MMMaqbool AYuldasheva NHall ASBraund PSDixon RJMangino MStevens SThompson JRBredin FTremelling MParkes MDrummond HLees CWNimmo ERSatsangi JFisher SAForbes ALewis CMOnnie CMPrescott NJSanderson JMatthew CGBarbour JMohiuddin MKTodhunter CEMansfield JCAhmad TCummings FRJewell DP. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Nature Genetics.
39:1329-1337.
2007
Full text if available -
Teo YYInouye MSmall KSGwilliam RDeloukas PKwiatkowski DPClark TG. A genotype calling algorithm for the Illumina BeadArray platform.
Bioinformatics.
23:2741-2746.
2007
Full text if available -
van Heel DAFranke LHunt KAGwilliam RZhernakova AInouye MWapenaar MCBarnardo MCNMBethel GHolmes GKTFeighery CJewell DKelleher DKumar PTravis SWalters JRFSanders DSHowdle PSwift JPlayford RJMcLaren WMMearin MLMulder CJMcManus RMcGinnis RCardon LRDeloukas PWijmenga C. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
Nature Genetics.
39:827-829.
2007
Full text if available -
Inouye MBurton PRClayton DGCardon LRCraddock NDeloukas PDuncanson AKwiatkowski DPMcCarthy MIOuwehand WHSamani NJTodd JADonnelly PBarrett JCDavison DEaston DEvans DLeung HTMarchini JLMorris APSpencer CCATobin MDAttwood APBoorman JPCant BEverson UHussey JMJolley JDKnight ASKoch KMeech ENutland SProwse CVStevens HETaylor NCWalters GRWalker NMWatkins NAWinzer TJones RWMcArdle WLRing SMStrachan DPPembrey MBreen GSt. Clair DCaesar SGordon-Smith KJones LFraser CGreen EKGrozeva DHamshere MLHolmans PAJones IRKirov GMoskvina VNikolov IO'Donovan MCOwen MJCollier DAElkin AFarmer AWilliamson RMcGuffin PYoung AHFerrier INBall SGBalmforth AJBarrett JHBishop DTIles MMMaqbool AYuldasheva NHall ASBraund PSDixon RJMangino MStevens SThompson JRBredin FTremelling MParkes MDrummond HLees CWNimmo ERSatsangi JFisher SAForbes ALewis CMOnnie CMPrescott NJSanderson JMathew CGBarbour JMohiuddin MKTodhunter CEMansfield JCAhmad TCummings FRJewell DP. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature.
447:661-678.
2007
Full text if available -
Ngan S-CInouye MTSamudrala R. A knowledge-based scoring function based on residue triplets for protein structure prediction.
Protein Engineering Design and Selection.
19:187-193.
2006
Full text if available
-
Bond STKing EJHenstridge DCTran AMoody SCYang CLiu YMellett NANath APInouye MTarling EJde Aguiar Vallim TQMeikle PJCalkin ACDrew BG. Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance.
Nature Communications.
12.
2021
-
chapter
-
Byars SGInouye M. Genome-wide association studies and risk scores for coronary artery disease: Sex biases.
Advances in Experimental Medicine and Biology.
627-642.
2018
Full text if available -
Inouye MTeo YY. Genotype Calling.
69-86.
2011
Full text if available
-
Byars SGInouye M. Genome-wide association studies and risk scores for coronary artery disease: Sex biases.
Advances in Experimental Medicine and Biology.
627-642.
2018
-
conference paper
-
Kraft PWand HLambert SATamburro CMacArthur JIacocca MASillari CO'Sullivan JBrockman DSchuele BVenner EKullo IJRowley RMcCarthy MAntoniou ACEaston DFHegele RAKhera AKooperberg CEdwards KOrmond KEKhoury MJJanssens ACJWGoddard KABInouye MWojcik G. Establishing polygenic risk score reporting standards and a polygenic score catalog to improve validation, interpretation and reproducibility.
Genetic Epidemiology.
496-497.
2020
-
Canovas RAbraham GCobb JBrozynska MBowes JSmith SEllis JHakonarson HThomson WInouye MMunro J. GENOMIC RISK SCORES FOR PREDICTING JUVENILE IDIOPATHIC ARTHRITIS.
Internal Medicine Journal.
32-32.
2020
-
Tang HHFLang AEvans MJackson DJLemanske RGern JTeo SMJudd LMHolt PSly PHolt KEInouye M. THE EARLY-LIFE NASOPHARYNGEAL MICROBIOME INTERACTS WITH ALLERGIC AND NON-ALLERGIC MECHANISMS OF CHILDHOOD WHEEZE.
Internal Medicine Journal.
22-23.
2019
-
Palmu JWatrous JHavulinna ALagerborg KSalosensaari ALahti LRitchie SInouye MCheng SSalomaa VJain MNiiranen T. Eicosanoid Variation is Strongly Related to Blood Pressure in the General Population.
Circulation.
2018
-
Lang AHolt KEInouye MHolt PGTeo SMTang HHFJudd LMLemanske RFEvans MDJackson DJGern JE. Nasopharyngeal Microbiome During Health and Illness in Early Life.
Journal of Allergy and Clinical Immunology.
AB109-AB109.
2018
-
March LWillers CEllis JCobb JLester SBuchbinder RWechalekar MMunro JBenham HJackson CXue MHill CKenna TKeen HPerera CHassett GSingh-Grewal DRichards BLassere MYoussef PLim IWalsh PThomas RBrown MAdib NBarrett CNg JRischmueller MBoros CProudman SChessman DSinnathurai POakley SChaitow JDowdie PChafield SInouye MKubler PTymms KKelly ATsai TRaj ADKhoo KHannan RNinan JPontifex EMurray K. THE AUSTRALIAN ARTHRITIS AND AUTOIMMUNE BIOBANK COLLABORATIVE (A3BC) PROTOCOL.
Internal Medicine Journal.
23-24.
2018
-
Hamilton ALKamm MATeo S-MDe Cruz PWright EKFeng HRitchie KJKirkwood CDInouye M. Post-operative Crohn's disease recurrence is associated with specific changes in the faecal microbiome - potential pathogenic and protective roles.
Journal of Crohn's and Colitis.
S476-S476.
2017
-
Hamilton ALKamm MATeo S-MDe Cruz PWright EKFeng HRitchie KJSung JJKirkwood CDInouye M. Post-operative Crohn's disease recurrence is associated with specific changes in the fecal microbiome: Potential pathogenic and protective roles.
Journal of Gastroenterology and Hepatology.
117-118.
2017
-
Goldberg GChatfield SMurphy JD'Silva DPang ESO'Neill CTadros SGrebe KChen YSmyth GNg MInouye MBusfield SWilson MAndrews AWilson NWicks I. Evidence for a key role for neutrophils in rheumatoid arthritis.
European Journal of Immunology.
411-411.
2016
-
Havulinna ASAbraham GKristiansson KPerola MSalomaa VInouye MRipatti S. Genomic Prediction of Type 2 Diabetes and Coronary Heart Disease Following Diabetes.
Human Heredity: international journal of human and medical genetics.
221-221.
2016
-
Wang ZWan YZhang AQiu CQuinones-Parra SLoh LNguyen ORen YThomas PInouye MZhang XDoherty PXu JKedzierska K. Immunity to the newly emerged A/H7N9 influenza virus.
European Journal of Immunology.
623-623.
2016
-
Holt PGTeo SMMok DPham KKusel MSerralha MTroy NHolt BJHales BWalker MLHollams EMBochkov YHGrindle KJohnston SLGern JESly PDHolt KEInouye M. Cohort-wide characterization of the nasopharyngeal microbiome across year 1 in "high risk" infants by PCR and 16S rRNA gene deep sequencing: elucidation of viral-bacterial-host interactions driving early atopic asthma pathogenesis.
Allergy.
111-112.
2015
-
Wright EKKamm MADe Cruz PPrincen FSelvaraj FWagner JTeo SMHamilton ALRitchie KKrejany EOGorelik ALiew DPrideaux LLawrence ICAndrews JMBampton PAJakobovits SLFlorin THGibson PRDebinski HMacrae FASamuel DKronborg IRadford-Smith GGearry RBSelby WJohnston MJWoods RElliott PRBell SJBrown SJConnell WRDesmond PVSingh SInouye MKirkwood CD. What causes post-operative Crohn's disease recurrence? Evaluation of gut microbiota, anti-TNF non-response and smoking.
Journal of Gastroenterology and Hepatology.
145-146.
2015
-
Wright EKamm MWagner JTeo SMDe Cruz PHamilton ARitchie KInouye MKirkwood C. What causes recurrence of Crohn's Disease after intestinal resection? A prospective evaluation of microbiota, smoking and anti-TNF therapy. Results from the POCER study.
Journal of Crohn's and Colitis.
S436-S436.
2015
-
Reumann MMakalic EGoudey BWInouye MBickerstaffe ABui MPark DJKapuscinski MKSchmidt DFZhou ZQian GZobel JWagner JHopper JL. Supercomputing enabling exhaustive statistical analysis of genome wide association study data: Preliminary results.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
1258-1261.
2012
Full text if available -
Reumann MMakalic EGoudey BWInouye MBickerstaffe ABui MPark DJKapuscinski MKSchmidt DFZhou ZQian GZobel JWagner JHopper JL. Supercomputing enabling exhaustive statistical analysis of genome wide association study data: Preliminary results.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
1258-1261.
2012
Full text if available -
Church PCGoscinski AHolt KInouye MGhoting AMakarychev KReumann M. Design of multiple sequence alignment algorithms on parallel, distributed memory supercomputers.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
924-927.
2011
Full text if available -
Goudey BWang QRawlinson DZarnegar AKikianty EMarkham JMacintyre GAbraham GStern LInouye MHaviv IKowalczyk A. Replication of epistatic DNA loci in two case-control GWAS studies using OPE algorithm.
BMC Bioinformatics.
2011
Full text if available -
Wang JJXie JInouye MLiew GMitchell PBaird PNWong THarrap S. GENOME-WIDE ASSOCIATION STUDY OF RETINAL ARTERIOLAR DIMENSIONS AND INTERACTION WITH CORONARY RISK FACTORS.
Hypertension.
120-120.
2011
-
Richards JRivadeneira FInouye MPastinen TSoranzo NWilson SGAndrew TFalchi MGwilliam RAhmadi KRArp PValdes AMWhittaker PVerlaan DJJhamai MKumanduri Vvan Meurs JBHofman APols HPHart DZhai GMullin BHDeloukas PUitterlinden AGSpector TD. Genome-Wide Association Study Reveals Genetic Variants Associated with Bone Mineral Density, Osteoporosis and Osteoporotic Fractures.
Journal of Bone and Mineral Research.
S184-S184.
2008
-
Zhao JHLi SLuan JATan QWheeler EDebenham SInouye MDeloukas PSandhu MBarroso IMcGinnis RLoos RWareham NJ. Continuous and discrete association analyses of body mass index and obesity.
Genetic Epidemiology.
652-652.
2007
-
Kraft PWand HLambert SATamburro CMacArthur JIacocca MASillari CO'Sullivan JBrockman DSchuele BVenner EKullo IJRowley RMcCarthy MAntoniou ACEaston DFHegele RAKhera AKooperberg CEdwards KOrmond KEKhoury MJJanssens ACJWGoddard KABInouye MWojcik G. Establishing polygenic risk score reporting standards and a polygenic score catalog to improve validation, interpretation and reproducibility.
Genetic Epidemiology.
496-497.
2020
-
editorial article
-
Inouye MLannelongue L. Gene Regulatory Networks to Explain Coronary Artery Disease Heritability.
Journal of the American College of Cardiology.
73:2958-2960.
2019
Full text if available -
Inouye MAbraham G. Look, no hands! Spectral biomarkers from genetic association studies.
Genome Medicine: medicine in the post-genomic era.
5:14-14.
2013
Full text if available
-
Inouye MLannelongue L. Gene Regulatory Networks to Explain Coronary Artery Disease Heritability.
Journal of the American College of Cardiology.
73:2958-2960.
2019
-
erratum
-
Inouye MIglesias AIMishra AVitart VBykhovskaya YHöhn RSpringelkamp HCuellar-Partida GGharahkhani PBailey JNCWilloughby CELi XYazar SNag AKhawaja APPolašek OSiscovick DMitchell PTham YCHaines JLKearns LSHayward CShi Yvan Leeuwen EMTaylor KDBonnemaijer PRotter JIMartin NGZeller TMills RASouzeau EStaffieri SEJonas JBSchmidtmann IBoutin TKang JHLucas SEMWong TYBeutel MEWilson JFUitterlinden AGVithana ENFoster PJHysi PGHewitt AWKhor CCPasquale LRMontgomery GWKlaver CCWAung TPfeiffer NMackey DAHammond CJCheng C-YCraig JERabinowitz YSWiggs JLBurdon KPvan Duijn CMMacGregor S. Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Nature Communications.
2019
Full text if available -
Inouye MIngle DJValcanis MKuzevski ATauschek MInouye MStinear TLevine MMRobins-Browne RMHolt KE. Corrigendum: In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.
Microbial Genomics.
e000109.
2017
Full text if available
-
Inouye MIglesias AIMishra AVitart VBykhovskaya YHöhn RSpringelkamp HCuellar-Partida GGharahkhani PBailey JNCWilloughby CELi XYazar SNag AKhawaja APPolašek OSiscovick DMitchell PTham YCHaines JLKearns LSHayward CShi Yvan Leeuwen EMTaylor KDBonnemaijer PRotter JIMartin NGZeller TMills RASouzeau EStaffieri SEJonas JBSchmidtmann IBoutin TKang JHLucas SEMWong TYBeutel MEWilson JFUitterlinden AGVithana ENFoster PJHysi PGHewitt AWKhor CCPasquale LRMontgomery GWKlaver CCWAung TPfeiffer NMackey DAHammond CJCheng C-YCraig JERabinowitz YSWiggs JLBurdon KPvan Duijn CMMacGregor S. Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Nature Communications.
2019
-
other publication
-
Abraham GQiu YInouye M. FlashPCA2: principal component analysis of Biobank-scale genotype datasets.
Bioinformatics.
2776-2778.
2017
Full text if available
-
Abraham GQiu YInouye M. FlashPCA2: principal component analysis of Biobank-scale genotype datasets.
Bioinformatics.
2776-2778.
2017