selected publications
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academic article
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Inouye MLannelongue L. Gene Regulatory Networks to Explain Coronary Artery Disease Heritability.
Journal of the American College of Cardiology.
73:2958-2960.
2019
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Nath APBraun ARitchie SCCarbone FRMackay LKGebhardt TInouye M. Comparative analysis reveals a role for TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells.
PLoS ONE.
14.
2019
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Méric GWick RRWatts SCHolt KEInouye M. Correcting index databases improves metagenomic studies.
BioXRiv.
2019
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Watts SCRitchie SCInouye MHolt KE. FastSpar: rapid and scalable correlation estimation for compositional data.
Bioinformatics.
35:1064-1066.
2019
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Teo SMTang HHFMok DJudd LMWatts SCPham KHolt BJKusel MSerralha MTroy NBochkov YAGrindle KLemanske RFJohnston SLGern JESly PDHolt PGHolt KEInouye M. Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease.
Cell Host and Microbe.
24:341-352.
2018
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Kettunen JRitchie SCAnufrieva OLyytikäinen LPHernesniemi JKarhunen PJKuukasjärvi PLaurikka JKähönen MLehtimäki THavulinna ASSalomaa VMännistö SAla-Korpela MPerola MInouye MWürtz P. Biomarker Glycoprotein Acetyls is Associated with the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients.
Circulation: Genomic and Precision Medicine.
11.
2018
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Holt KEMcAdam PThai PVKThuong NTTHa DTMLan NNLan NHNhu NTQHai HTHa VTNThwaites GEdwards DJNath APPham KAscher DBFarrar JKhor CCTeo YYInouye MCaws MDunstan SJ. Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam.
Nature Genetics.
50:849-856.
2018
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Inouye MAbraham GNelson CPWood AMSweeting MJDudbridge FLai FYKaptoge SBrozynska MWang TYe SWebb TRRutter MKTzoulaki IPatel RSLoos RJFKeavney BHemingway HThompson JWatkins HDeloukas PDi Angelantonio EButterworth ASDanesh JSamani NJ. Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Journal of the American College of Cardiology.
72:1883-1893.
2018
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Bhalala OGNath APRyten MWeale MEHardy JD'Sa KRamasamy ATrabzuni DGuelfi SBotia JAVandrovcova JSmith CWalker RInouye MSibley CR. Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.
PLoS Genetics.
14:1-25.
2018
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Huang QQRitchie SCBrozynska MInouye M. Power, false discovery rate and Winner's Curse in eQTL studies.
Nucleic Acids Research.
46:1-12.
2018
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Tang HHFTeo SMBelgrave DCMEvans MDJackson DJBrozynska MKusel MMHJohnston SLGern JELemanske RFSimpson ACustovic ASly PDHolt PGHolt KEInouye M. Trajectories of childhood immune development and respiratory health relevant to asthma and allergy.
eLife.
7:1-31.
2018
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Renz HHolt PGInouye MLogan ACPrescott SLSly PD. An exposome perspective: Early-life events and immune development in a changing world.
Journal of Allergy and Clinical Immunology.
140:24-40.
2017
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Nath APRitchie SCByars SGFearnley LGHavulinna ASJoensuu AKangas AJSoininen PWennerström AMilani LMetspalu AMännistö SWürtz PKettunen JRaitoharju EKähönen MJuonala MPalotie AAla-Korpela MRipatti SLehtimäki TAbraham GRaitakari OSalomaa VPerola MInouye M. An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.
Genome Biology: biology for the post-genomic era.
18.
2017
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Marques FZPrestes PRByars SGRitchie SCWürtz PPatel SKBooth SARana IMinoda YBerzins SPCurl CLBell JRWai BSrivastava PMKangas AJSoininen PRuohonen SKähönen MLehtimäki TRaitoharju EHavulinna APerola MRaitakari OSalomaa VAla‐Korpela MKettunen JMcGlynn MKelly JWlodek MELewandowski PADelbridge LMBurrell LMInouye MHarrap SBCharchar FJ. Experimental and human evidence for Lipocalin‐2 (Neutrophil Gelatinase‐Associated Lipocalin [NGAL]) in the development of cardiac hypertrophy and heart failure.
Journal of the American Heart Association.
6.
2017
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Byars SGHuang QQGray L-ABakshi ARipatti SAbraham GStearns SCInouye M. Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
PLoS Genetics.
13.
2017
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Gray L-AD’Antoine HATong SYCMcKinnon MBessarab DBrown NReményi BSteer ASyn GBlackwell JMInouye MCarapetis JR. Genome-wide analysis of genetic risk factors for rheumatic heart disease in Aboriginal Australians provides support for pathogenic molecular mimicry.
Journal of Infectious Diseases.
216:1460-1470.
2017
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Goudey BAbraham GKikianty EWang QRawlinson DShi FHaviv IStern LKowalczyk AInouye M. Interactions within the MHC contribute to the genetic architecture of celiac disease.
PLoS ONE.
12.
2017
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Wright EKKamm MAWagner JTeo S-MCruz PDHamilton ALRitchie KJInouye MKirkwood CD. Microbial Factors Associated with Postoperative Crohn’s Disease Recurrence.
Journal of Crohn's and Colitis.
11:191-203.
2017
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Hollams EMTeo SMKusel MHolt BJHolt KEInouye MDe Klerk NHZhang GSly PDHart PHHolt PG. Vitamin D over the first decade and susceptibility to childhood allergy and asthma.
Journal of Allergy and Clinical Immunology.
139:472-481.
2017
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Abraham GQiu YInouye M. FlashPCA2: principal component analysis of biobank-scale genotype datasets
2016
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Bhalala OGNath APInouye MSibley CR. Identification of Brain Expression Quantitative Trait Loci Associated with Schizophrenia and Affective Disorders in Normal Brain Tissue
2016
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Ritchie SCWatts SFearnley LGHolt KEAbraham GInouye M. A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets.
Cell Systems.
3:71-82.
2016
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Abraham GHavulinna ASBhalala OGByars SGDe Livera AMYetukuri LTikkanen EPerola MSchunkert HSijbrands EJPalotie ASamani NJSalomaa VRipatti SInouye M. Genomic prediction of coronary heart disease.
European Heart Journal.
37:3267-3278.
2016
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Holt KEIngle DJLevine MMKuzevski AValcanis MRobins-Browne RMTauschek MInouye MStinear T. In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.
Microbial Genomics.
2.
2016
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Shu LZhao YKurt ZByars SGTukiainen TKettunen JOrozco LDPellegrini MLusis AJRipatti SZhang BInouye MMäkinen V-PYang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.
BMC Genomics.
17.
2016
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Fearnley LGInouye M. Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks.
International Journal of Epidemiology.
45:1319-1328.
2016
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Abraham GRohmer ATye-Din JAInouye M. Genomic prediction of celiac disease targeting HLA-positive individuals.
Genome Medicine: medicine in the post-genomic era.
7.
2015
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Abraham GInouye M. Genomic risk prediction of complex human disease and its clinical application.
Current Opinion in Genetics and Development.
33:10-16.
2015
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Goudey BAbedini MHopper JLInouye MMakalic ESchmidt DFWagner JZhou ZZobel JReumann M. High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies.
Health Information Science and Systems.
3.
2015
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Martin WJSteer ACSmeesters PRKeeble JInouye MCarapetis JWicks IP. Post-infectious group A streptococcal autoimmune syndromes and the heart.
Autoimmunity Reviews.
14:710-725.
2015
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Wright EKKamm MATeo SMInouye MWagner JKirkwood CD. Recent advances in characterizing the gastrointestinal microbiome in Crohn's disease: A systematic review.
Inflammatory Bowel Diseases.
21:1219-1228.
2015
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Wang ZWan YQiu CQuiñones-Parra SZhu ZLoh LTian DRen YHu YZhang XThomas PGInouye MDoherty PCKedzierska KXu J. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells.
Nature Communications.
6.
2015
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Ritchie SCWürtz PNath APAbraham GHavulinna ASFearnley LGSarin A-PKangas AJSoininen PAalto KSeppälä IRaitoharju ESalmi MMaksimow MMännistö SKähönen MJuonala MRipatti SLehtimäki TJalkanen SPerola MRaitakari OSalomaa VAla-Korpela MKettunen JInouye M. The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection.
Cell Systems.
1:293-301.
2015
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Teo SMMok DPham KKusel MSerralha MTroy NHolt BJHales BJWalker MLHollams EBochkov YAGrindle KJohnston SLGern JESly PDHolt PGHolt KEInouye M. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development.
Cell Host and Microbe.
17:704-715.
2015
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Shi WLiao YWillis SNTaubenheim NInouye MTarlinton DMSmyth GKHodgkin PDNutt SLCorcoran LM. Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.
Nature Immunology.
16:663-673.
2015
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Inouye MAbraham G. Correction: Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning.
PLoS Genetics.
10:e1004374-e1004374.
2014
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Abraham GTye-Din JABhalala OGKowalczyk AZobel JInouye M. Accurate and robust genomic prediction of Celiac disease using statistical learning.
PLoS Genetics.
10.
2014
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Lim ETWürtz PHavulinna ASPalta PTukiainen TRehnström KEsko TMägi RInouye MLappalainen TChan YSalem RMLek MFlannick JSim XManning ALadenvall CBumpstead SHämäläinen EAalto KMaksimow MSalmi MBlankenberg SArdissino DShah SHorne BMcPherson RHovingh GKReilly MPWatkins HGoel AFarrall MGirelli DReiner APStitziel NOKathiresan SGabriel SBarrett JCLehtimäki TLaakso MGroop LKaprio JPerola MMcCarthy MIBoehnke MAltshuler DMLindgren CMHirschhorn JNMetspalu AFreimer NBZeller TJalkanen SKoskinen SRaitakari ODurbin RMacArthur DGSalomaa VRipatti SDaly MJPalotie A. Distribution and medical impact of loss-of-function variants in the Finnish founder population.
PLoS Genetics.
10.
2014
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Walker MLHolt KEAnderson GPTeo SMSly PDHolt PGInouye M. Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy.
Frontiers in Immunology.
5.
2014
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Abraham GInouye M. Fast principal component analysis of large-scale genome-wide data.
PLoS ONE.
9.
2014
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Hysi PGCheng C-YSpringelkamp HMacgregor SBailey JNCWojciechowski RVitart VNag AHewitt AWHöhn RVenturini CMirshahi ARamdas WDThorleifsson GVithana EKhor C-CStefansson ABLiao JHaines JLAmin NWang YXWild PSOzel ABLi JZFleck BWZeller TStaffieri SETeo Y-YCuellar-Partida GLuo XAllingham RRRichards JESenft AKarssen LCZheng YBellenguez CXu LIglesias AIWilson JFKang JHvan Leeuwen EMJonsson VThorsteinsdottir UDespriet DDGEnnis SMoroi SEMartin NGJansonius NMYazar STai E-SAmouyel PKirwan Jvan Koolwijk LMEHauser MAJonasson FLeo PLoomis SJFogarty RRivadeneira FKearns LLackner KJde Jong PTVMSimpson CLPennell CEOostra BAUitterlinden AGSaw S-MLotery AJBailey-Wilson JEHofman AVingerling JRMaubaret CPfeiffer NWolfs RCWLemij HGYoung TLPasquale LRDelcourt CSpector TDKlaver CCWSmall KSBurdon KPStefansson KWong T-YPaul MWang JJRochtchina EAttia JScott RHolliday EWong TYBaird PMXie JInouye MViswanath ASim XAllingham RRBrillian MBudenz DCooke Bailey JNChristen WGFingert JFriedman DSGaasterland DGaasterland THaines JLHauser MAKang JHKraft PLee RKLichter PALiu YLoomis SJMoroi SEPasquale LRPericak-Vance MARealini ARichards JESchuman JSScott WKSingh KSit AJVollrath DWeinreb RNWiggs JLWollstein GZack DJZhang KDonnelly PBarroso IBlackwell JMBramon EBrown MACasas JPCorvin ADeloukas PDuncanson AJankowski JMarkus HSMathew CGPalmer CNAPlomin RRautanen ASawcer SJTrembath RCViswanathan ACWood NWSpencer CCABand GBellenguez CFreeman CHellenthal GGiannoulatou EPirinen MPearson RStrange ASu ZVukcevic DDonnelly PLangford CHunt SEEdkins SGwilliam RBlackburn HBumpstead SJDronov SGillman MGray EHammond NJayakumar AMcCann OTLiddle JPotter SCRavindrarajah RRicketts MWaller MWeston PWidaa SWhittaker PBarroso IDeloukas PViswanathan AMackey DACraig JEWiggs JLvan Duijn CMHammond CJAung T. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
Nature Genetics.
46:1126-1130.
2014
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Springelkamp HHöhn RMishra AHysi PGKhor C-CLoomis SJBailey JNCGibson JThorleifsson GJanssen SFLuo XRamdas WDVithana ENongpiur MEMontgomery GWXu LMountain JEGharahkhani PLu YAmin NKarssen LCSim K-Svan Leeuwen EMIglesias AIVerhoeven VJMHauser MALoon S-CDespriet DDGNag AVenturini CSanfilippo PGSchillert AKang JHLanders JJonasson FCree AJvan Koolwijk LMERivadeneira FSouzeau EJonsson VMenon GMitchell PWang JJRochtchina EAttia JScott RHolliday EGWong T-YBaird PNXie JInouye MViswanathan ASim XWeinreb RNde Jong PTVMOostra BAUitterlinden AGHofman AEnnis SThorsteinsdottir UBurdon KPAllingham RRBrilliant MHBudenz DLCooke Bailey JNChristen WGFingert JFriedman DSGaasterland DGaasterland THaines JLHauser MAKang JHKraft PLee RKLichter PRLiu YLoomis SJMoroi SEPasquale LRPericak-Vance MARealini ARichards JESchuman JSScott WKSingh KSit AJVollrath DWeinreb RNWiggs JLWollstein GZack DJZhang KDonnelly PBarroso IBlackwell JMBramon EBrown MACasas JPCorvin ADeloukas PDuncanson AJankowski JMarkus HSMathew CGPalmer CNAPlomin RRautanen ASawcer SJTrembath RCViswanathan ACWood NWSpencer CCABand GBellenguez CFreeman CHellenthal GGiannoulatou EPirinen MPearson RStrange ASu ZVukcevic DLangford CHunt SEEdkins SGwilliam RBlackburn HBumpstead SJDronov SGillman MGray EHammond NJayakumar AMcCann OTLiddle JPotter SCRavindrarajah RRicketts MWaller MWeston PWidaa SWhittaker PSpector TDMirshahi ASaw S-MVingerling JRTeo Y-YHaines JLWolfs RCWLemij HGTai E-SJansonius NMJonas JBCheng C-YAung TViswanathan ACKlaver CCWCraig JEMacgregor SMackey DALotery AJStefansson KBergen AABYoung TLPfeiffer NWong T-YHewitt AWvan Duijn CMHammond CJ. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.
Nature Communications.
5.
2014
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Inouye MDashnow HRaven L-ASchultz MBPope BJTomita TZobel JHolt KE. SRST2: Rapid genomic surveillance for public health and hospital microbiology labs.
Genome Medicine: medicine in the post-genomic era.
6.
2014
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Carotta SWillis SNHasbold JInouye MPang SHMEmslie DLight AChopin MShi WWang HMorse HCTarlinton DMCorcoran LMHodgkin PDNutt SL. The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Journal of Experimental Medicine.
211:2169-2181.
2014
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Abraham GBhalala OGde Bakker PIWRipatti SInouye M. Towards a molecular systems model of coronary artery disease.
Current Cardiology Reports.
16.
2014
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Goudey BRawlinson DWang QShi FFerra HCampbell RMStern LInouye MTOng CSKowalczyk A. GWIS - model-free, fast and exhaustive search for epistatic interactions in case-control GWAS.
BMC Genomics.
14.
2013
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Sim XJensen RAIkram MKCotch MFLi XMacGregor SXie JSmith AVBoerwinkle EMitchell PKlein RKlein BEKGlazer NLLumley TMcKnight BPsaty BMde Jong PTVMHofman ARivadeneira FUitterlinden AGvan Duijn CMAspelund TEiriksdottir GHarris TBJonasson FLauner LJAttia JBaird PNHarrap SHolliday EGInouye MRochtchina EScott RJViswanathan ALi GSmith NLWiggins KLKuo JZTaylor KDHewitt AWMartin NGMontgomery GWSun CYoung TLMackey DAvan Zuydam NRDoney ASFPalmer CNAMorris ADRotter JITai ESGudnason VVingerling JRSiscovick DSWang JJWong TY. Genetic loci for retinal arteriolar microcirculation.
PLoS ONE.
8.
2013
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Holliday EGSmith AVCornes BKBuitendijk GHSJensen RASim XAspelund TAung TBaird PNBoerwinkle ECheng CYvan Duijn CMEiriksdottir GGudnason VHarris THewitt AWInouye MJonasson FKlein BEKLauner LLi XLiew GLumley TMcElduff PMcKnight BMitchell PPsaty BMRochtchina ERotter JIScott RJTay WTaylor KTeo YYUitterlinden AGViswanathan AXie SVingerling JRKlaver CCWTai ESSiscovick DKlein RCotch MFWong TYAttia JWang JJ. Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis.
PLoS ONE.
8.
2013
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Stambolian DWojciechowski ROexle KPirastu MLi XRaffel LJCotch MFChew EYKlein BKlein RWong TYSimpson CLKlaver CCWvan Duijn CMVerhoeven VJMBaird PNVitart VPaterson ADMitchell PSaw SMFossarello MKazmierkiewicz KMurgia FPortas LSchache MRichardson AXie JWang JJRochtchina EViswanathan ACHayward CWright AFPolašek OCampbell HRudan IOostra BAUitterlinden AGHofman ARivadeneira FAmin NKarssen LCVingerling JRHosseini SMDöring ABettecken TVatavuk ZGieger CWichmann H-EWilson JFFleck BFoster PJTopouzis FMcGuffin PSim XInouye MHolliday EGAttia JScott RJRotter JIMeitinger TBailey-Wilson JE. Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.
Human Molecular Genetics.
22:2754-2764.
2013
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Abraham GKowalczyk AZobel JInouye M. Performance and robustness of penalized and unpenalized methods for genetic prediction of complex human disease.
Genetic Epidemiology.
37:184-195.
2013
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Mackay LKRahimpour AMa JZCollins NStock ATHafon M-LVega-Ramos JLauzurica PMueller SNStefanovic TTscharke DCHeath WRInouye MCarbone FRGebhardt T. The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin.
Nature Immunology.
14:1294-1301.
2013
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Inouye MEyre SBowes JDiogo DLee ABarton AMartin PZhernakova AStahl EViatte SMcAllister KAmos CIPadyukov LToes REMHuizinga TWJWijmenga CTrynka GFranke LWestra H-JAlfredsson LHu XSandor Cde Bakker PIWDavila SKhor CCHeng KKAndrews REdkins SHunt SELangford CSymmons DConcannon POnengut-Gumuscu SRich SSDeloukas PGonzalez-Gay MARodriguez-Rodriguez LÄrlsetig LMartin JRantapää-Dahlqvist SPlenge RMRaychaudhuri SKlareskog LGregersen PKWorthington J. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
Nature Genetics.
44:1336-1340.
2012
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Abraham GKowalczyk AZobel JInouye M. SparSNP: Fast and memory-efficient analysis of all SNPs for phenotype prediction.
BMC Bioinformatics.
13.
2012
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Inouye MRipatti SKettunen JLyytikäinen L-POksala NLaurila P-PKangas AJSoininen PSavolainen MJViikari JKähönen MPerola MSalomaa VRaitakari OLehtimäki TTaskinen M-RJärvelin M-RAla-Korpela MPalotie Ade Bakker PIW. Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis.
PLoS Genetics.
8:e1002907-e1002907.
2012
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Reumann MMakalic EGoudey BWInouye MBickerstaffe ABui MPark DJKapuscinski MKSchmidt DFZhou ZQian GZobel JWagner JHopper JL. Supercomputing enabling exhaustive statistical analysis of genome wide association study data: Preliminary results.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
2012:1258-1261.
2012
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Kettunen JTukiainen TSarin A-POrtega-Alonso ATikkanen ELyytikäinen L-PKangas AJSoininen PWürtz PSilander KDick DMRose RJSavolainen MJViikari JKähönen MLehtimäki TPietiläinen KHInouye MMcCarthy MIJula AEriksson JRaitakari OTSalomaa VKaprio JJärvelin M-RPeltonen LPerola MFreimer NBAla-Korpela MPalotie ARipatti S. Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
Nature Genetics.
44:269-276.
2012
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Inouye MConway TCZobel JHolt KE. Short read sequence typing (SRST): multi-locus sequence types from short reads.
BMC Genomics.
13:338-338.
2012
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Ala-Korpela MKangas AJInouye M. Genome-wide association studies and systems biology: together at last.
Trends in Genetics.
27:493-498.
2011
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Church PCGoscinski AHolt KInouye MGhoting AMakarychev KReumann M. Design of multiple sequence alignment algorithms on parallel, distributed memory supercomputers.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
2011:924-927.
2011
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Waterworth DMRicketts SLSong KChen LZhao JHRipatti SAulchenko YSZhang WYuan XLim NLuan JAshford SWheeler EYoung EHHadley DThompson JRBraund PSJohnson TStruchalin MSurakka ILuben RKhaw K-TRodwell SALoos RJFBoekholdt SMInouye MDeloukas PElliott PSchlessinger DSanna SScuteri AJackson AMohlke KLTuomilehto JRoberts RStewart AKesäniemi YAMahley RWGrundy SMMcArdle WCardon LWaeber GVollenweider PChambers JCBoehnke MAbecasis GRSalomaa VJärvelin M-RRuokonen ABarroso IEpstein SEHakonarson HHRader DJReilly MPWitteman JCMHall ASSamani NJStrachan DPBarter Pvan Duijn CMKooner JSPeltonen LWareham NJMcPherson RMooser VSandhu MS. Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease.
Arteriosclerosis, Thrombosis and Vascular Biology.
30:2264-2276.
2010
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Surakka IKristiansson KAnttila VInouye MBarnes CMoutsianas LSalomaa VDaly MPalotie APeltonen LRipatti S. Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging.
Genome Research.
20:1344-1351.
2010
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Anttila VStefansson HKallela MTodt UTerwindt GMCalafato MSNyholt DRDimas ASFreilinger TMüller-Myhsok BArtto VInouye MAlakurtti KKaunisto MAHämäläinen EDe Vries BStam AHWeller CMHeinze AHeinze-Kuhn KGoebel IBorck GGöbel HSteinberg SWolf CBjörnsson AGudmundsson GKirchmann MHauge AWerge TSchoenen JEriksson JGHagen KStovner LWichmann HEMeitinger TAlexander MMoebus SSchreiber SAulchenko YSBreteler MMBUitterlinden AGHofman AVan Duijn CMTikka-Kleemola PVepsäläinen SLucae STozzi FMuglia PBarrett JKaprio JFärkkilä MPeltonen LStefansson KZwart JAFerrari MDOlesen JDaly MWessman MVan Den Maagdenberg AMJMDichgans MKubisch CDermitzakis ETFrants RRPalotie A. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.
Nature Genetics.
42:869-873.
2010
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Inouye MSilander KHamalainen ESalomaa VHarald KJousilahti PMännistö SEriksson JGSaarela JRipatti SPerola Mvan Ommen G-JBTaskinen M-RPalotie ADermitzakis ETPeltonen L. An Immune Response Network Associated with Blood Lipid Levels.
PLoS Genetics.
6:e1001113-e1001113.
2010
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Inouye MIglesias AIMishra AVitart VBykhovskaya YHöhn RSpringelkamp HCuellar-Partida GGharahkhani PBailey JNCWilloughby CELi XYazar SNag AKhawaja APPolašek OSiscovick DMitchell PTham YCHaines JLKearns LSHayward CShi Yvan Leeuwen EMTaylor KDBonnemaijer PRotter JIMartin NGZeller TMills RASouzeau EStaffieri SEJonas JBSchmidtmann IBoutin TKang JHLucas SEMWong TYBeutel MEWilson JFUitterlinden AGVithana ENFoster PJHysi PGHewitt AWKhor CCPasquale LRMontgomery GWKlaver CCWAung TPfeiffer NMackey DAHammond CJCheng C-YCraig JERabinowitz YSWiggs JLBurdon KPvan Duijn CMMacGregor S. Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
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Inouye MIglesias AIMishra AVitart VBykhovskaya YHöhn RSpringelkamp HCuellar-Partida GGharahkhani PBailey JNCWilloughby CELi XYazar SNag AKhawaja APPolašek OSiscovick DMitchell PTham YCHaines JLKearns LSHayward CShi Yvan Leeuwen EMTaylor KDBonnemaijer PRotter JIMartin NGZeller TMills RASouzeau EStaffieri SEJonas JBSchmidtmann IBoutin TKang JHLucas SEMWong TYBeutel MEWilson JFUitterlinden AGVithana ENFoster PJHysi PGHewitt AWKhor CCPasquale LRMontgomery GWKlaver CCWAung TPfeiffer NMackey DAHammond CJCheng C-YCraig JERabinowitz YSWiggs JLBurdon KPvan Duijn CMMacGregor S. Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
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