Trans-Platinum(IV) pro-drugs that exhibit unusual resistance to reduction by endogenous reductants and blood serum but are rapidly activated inside cells: 1H NMR and XANES spectroscopy study Academic Article uri icon

abstract

  • All-trans diammine platinum complexes with four carboxylate donors are stable in the presence of l-ascorbate and blood serum, but are reduced rapidly in whole blood and in cancer cells.

publication date

  • 2020