Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China Academic Article uri icon


  • AbstractStringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.


  • Cao, S
  • Gan, Y
  • Wang, C
  • Bachmann, M
  • Wei, S
  • Gong, J
  • Huang, Y
  • Wang, T
  • Li, L
  • Lu, K
  • Jiang, Heng
  • Gong, Y
  • Xu, H
  • Shen, X
  • Tian, Q
  • Lv, C
  • Song, F
  • Yin, X
  • Lu, Z

publication date

  • November 20, 2020