Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization Academic Article uri icon


  • In the present study, the effect of nitroxyl anion (HNO) donors on factors that precede atherosclerosis was examined. They reduced endothelial cell inflammation and monocyte activation and as such may be an effective treatment for coronary artery disease.


  • Andrews, KL
  • Sampson, AK
  • Irvine, JC
  • Shihata, WA
  • Michell, DL
  • Lumsden, NG
  • Lim, C
  • Huet, O
  • Drummond, GR
  • Kemp-Harper, BK
  • Chin-Dusting, JPF

publication date

  • 2016