Family intervention may be helpful for people with psychosis. We reviewed the literature for family intervention for people with a first-onset psychosis. There is limited and conflicting evidence of the efficacy of family intervention for this population. Definitive randomized controlled trials are required to establish the efficacy. At this time, evidence suggests that in High Expressed Emotion (EE) families, family intervention is a possible effective intervention. We suggest caution in families with Low EE as one study suggests that in Low EE families, family intervention can increase the levels of EE.