Tuneable DNA-based asymmetric catalysis using a G-quadruplex supramolecular assembly Academic Article uri icon


  • Described is the first modular construction of a G-quadruplex chiral catalyst. The key objective was to use G-quadruplex structures to act as chiral ligands that would allow access to either enantiomer of the product of a Diels-Alder reaction.


  • Roe, Stephen
  • Ritson, Dougal J
  • Garner, Tom
  • Searle, Mark
  • Moses, John E

publication date

  • 2010