Studies on the Biomimetic Synthesis of SNF4435 C and D Academic Article uri icon


  • [reaction: see text] The biomimetic synthesis of the bicyclic core of the novel immunosuppresants SNF4435C and SNF4435D is reported. The core framework was efficiently generated from the all-trans tetraene precursor in one step and in good yield.


  • Moses, John E
  • Baldwin, Jack E
  • Marquez, Rodolfo
  • Adlington, Robert M
  • Cowley, Andrew R

publication date

  • October 2002