Prevalence of occult metastatic disease in patients undergoing18F-FDG PET for primary diagnosis or staging of lung carcinoma and solitary pulmonary nodules Academic Article uri icon


  • BACKGROUND: Accurate staging of lung cancer is essential in determining the most appropriate management plan, as detection of occult metastasis can significantly alter management. AIMS: The aims of this study are to determine the prevalence of occult metastasis in patients undergoing 2-(18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography (PET) for evaluation of suspected/proven lung carcinoma and correlate pre-PET TNM stage with prevalence of metastasis. METHODS: FDG-PET, which identified patients with metastasis on institutional database, was re-evaluated by a nuclear medicine physician blinded to clinical information. The confidence level of metastasis was scored on a 5-point scale, with a score of >/=4 considered positive. RESULTS: There were 67 of 645 (10%) patients identified with suspected occult metastasis on FDG-PET. Twelve patients scoring


  • Lee, ST
  • Berlangieri, SU
  • Poon, AMT
  • Mitchell, P
  • Pathmaraj, K
  • Tabone, K
  • Byrne, AJ
  • O?Keefe, GJ
  • Knight, SR
  • Clarke, CP
  • Scott, AM

publication date

  • November 1, 2007