Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids Academic Article uri icon

abstract

  • Antibodies raised against a Plasmodium falciparum protein expressed in Escherichia coli reacted with a 220,000-molecular weight antigen of mature blood-stage parasites. The protein resembles the sporozoite surface antigen being composed of tandem repeats of 11 amino acids. However, it is isolate-specific and the encoding gene is not detectable in strains that do not express the protein.

authors

  • Coppel, Ross L
  • Cowman, Alan F
  • Lingelbach, Klaus R
  • Brown, Graham V
  • Saint, Robert B
  • Kemp, David J
  • Anders, Robin F

publication date

  • December 1983

published in