Florence Nightingale stated that the art of nursing is to provide an environment in which the patient is in the best position for nature to act upon, and Martha Rogers, in turn, emphasized that one part in nursing is to pattern the environment into a place where healing conditions are optimal. This paper presents a preliminary conceptual framework that describes the influence of environment in palliative care. Based on previously published studies, a conceptual framework describing the influence of environments in palliative care was developed consisting of an atmosphere of hospitality; an atmosphere of safety; and, an atmosphere of 'everydayness'. The framework describes that the atmosphere is created in the meeting between the person's needs/expectations and the environment, an atmosphere that can influence experiential outcomes of 'at-homeness' or homelessness in the palliative care setting. In conclusion, this preliminary conceptual framework may contribute to nursing practice by providing a conceptual basis for actively reflecting on and evaluating the atmosphere in palliative care settings.