Bread matters: a national initiative to profile the genetic diversity of Australian wheat Academic Article uri icon

abstract

  • The large and complex genome of wheat makes genetic and genomic analysis in this important species both expensive and resource intensive. The application of next-generation sequencing technologies is particularly resource intensive, with at least 17 Gbp of sequence data required to obtain minimal (1×) coverage of the genome. A similar volume of data would represent almost 40× coverage of the rice genome. Progress can be made through the establishment of consortia to produce shared genomic resources. Australian wheat genome researchers, working with Bioplatforms Australia, have collaborated in a national initiative to establish a genetic diversity dataset representing Australian wheat germplasm based on whole genome next-generation sequencing data. Here, we describe the establishment and validation of this resource which can provide a model for broader international initiatives for the analysis of large and complex genomes.

authors

  • Edwards, David
  • Wilcox, Stephen
  • Barrero, Roberto A
  • Fleury, Delphine
  • Cavanagh, Colin R
  • Forrest, Kerrie L
  • Hayden, Matthew J
  • Moolhuijzen, Paula
  • Keeble-Gagnère, Gabriel
  • Bellgard, Matthew I
  • Lorenc, Michał T
  • Shang, Catherine A
  • Baumann, Ute
  • Taylor, Jennifer M
  • Morell, Matthew K
  • Langridge, Peter
  • Appels, Rudi
  • Fitzgerald, Anna

publication date

  • August 2012