Paraoxonase and other coronary risk factors in a community-based cohort Academic Article uri icon

abstract

  • Oxidative damage to circulating lipids and vascular tissues contributes to the initiation and progression of atherosclerosis. High density lipoprotein provides protection from atherosclerosis and the enzyme paraoxonase may contribute to this effect. The aim of the present study was to examine the trends in paraoxonase activity during the course of a community-directed life-style intervention, and relationships of paraoxonase activity to other coronary heart disease risk factors, in a cohort of Australian Aboriginal people.

authors

  • Cohen, Jacob
  • Jenkins, Alicia J
  • Karschimkus, Connie
  • Qing, Su
  • Lee, Chee Teik
  • O'Dea, Kerin
  • Best, James D
  • Rowley, Kevin G

publication date

  • October 2002

has subject area