Treatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry Academic Article uri icon


  • BACKGROUND:Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18-64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke. METHODS:Data from the Australian Stroke Clinical Registry (2010-2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons. RESULTS:Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18-64 years) were more often male (63 vs. 51%; p < 0.001), born in Australia (70 vs. 63%; p < 0.001), more often discharged home from acute care (56 vs. 38%; p < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; p < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56-1.93, p < 0.001). CONCLUSIONS:Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status.


  • Lannin, Natasha A
  • Anderson, Craig S
  • Kim, Joosup
  • Kilkenny, Monique
  • Bernhardt, Julie
  • Levi, Christopher
  • Dewey, Helen M
  • Bladin, Christopher
  • Hand, Peter
  • Castley, Helen
  • Hill, Kelvin
  • Faux, Steven
  • Grimley, Rohan
  • Grabsch, Brenda
  • Middleton, Sandy
  • Donnan, Geoffrey
  • Cadilhac, Dominique A

publication date

  • 2017