Factors Influencing Creatine Loading into Human Skeletal Muscle Academic Article uri icon


  • This review describes several factors involved in regulating skeletal muscle creatine uptake and total creatine content. Skeletal muscle total creatine content increases with oral creatine supplementation, although the response is variable. Factors that may account for this variation are carbohydrate intake, physical activity, training status, and possibly fiber type.

publication date

  • July 2003