Enantioselective Synthesis ofl-CCG-I† Academic Article uri icon


  • Introduction of natural menthol as the chiral auxiliary in a gamma-Br-alpha,beta-unsaturated ester leads to enantioselective generation of three chiral centers in a single step on reaction with a glycine anion equivalent to provide L-CCG-I in 94% ee.


  • Chavan, Subhash P
  • Sharma, Pallavi
  • Sivappa, Rasapalli
  • Bhadbhade, Mohan M
  • Gonnade, Rajesh G
  • Kalkote, Uttam R

publication date

  • August 2003