Plasma protease inhibitor (PI) system in the laboratory opossum,Monodelphis domestica Academic Article uri icon

abstract

  • Protease inhibitor (PI) polymorphism was observed in the laboratory opossum, Monodelphis domestica, by either one-dimensional acid polyacrylamide gel electrophoresis (PAGE; pH 4.6) or isoelectric focusing (pH 3.5-5.0) followed by immunoblotting with rabbit antiserum to human alpha 1-antitrypsin; but acid PAGE produced superior resolution of the PI proteins. Family studies demonstrated an inheritance of nine codominant autosomal alleles, PID, PIE, PIF, PIG, PIH, PII, PIJ, PIK, and PIM, and a population study revealed frequencies of 0.411, 0.010, 0.341, 0.034, 0.023, 0.071, 0.035, 0.020, and 0.055, respectively.

authors

  • Oorschot, Roland
  • Arthur, Helen
  • Bell, Kevin
  • VandeBerg, John L
  • van Oorschot, Roland AK

publication date

  • October 1996