Simultaneous liver-pancreas-duodenum transplantation: one case report and review of the literature Academic Article uri icon


  • OBJECTIVE: To investigate the effect of treatment on end-stage liver disease and type-I diabetes mellitus with simultaneous liver-pancreas-duodenum transplantation. METHOD: In September 2003, one patient with chronic hepatitis B, liver cirrhosis, hepatic cellular cancer, and insulin-dependent diabetes received simultaneous orthotopic liver and heterotopic pancreas-duodenum transplantation. Liver and pancreas graft function was monitored after transplantation. RESULTS: The function of pancreas allograft was recovered immediately and the patient became insulin-independence postoperatively. The liver allograft was experienced an acute rejection episode and reversed by intravenous bolus methylprednisolone. The recipient was currently liver disease-free and insulin-free more than 21 months. CONCLUSIONS: The simultaneous liver-pancreas-duodenum transplantation is an effective method in the treatment of end-stage liver disease and type-I diabetes mellitus.


  • Xu, J
  • Yu, LX
  • Deng, WF
  • Fu, SJ
  • Du, CF
  • Wang, YB
  • Liu, XY
  • Miao, Y
  • Li, CJ
  • Ye, JS

publication date

  • January 1, 2006