Isolation and partial characterisation of a 26 kilodalton antigen from Plasmodium falciparum recognised by an inhibitory monoclonal antibody Academic Article uri icon

abstract

  • A 26 kDa protein, present in trophozoites and schizonts of Plasmodium falciparum, has been identified as the target of a monoclonal antibody that weakly inhibits parasite growth in vitro. The antigen has been purified to homogeneity by immuno-affinity chromatography and electrophoresis. The sequence of 19 amino acids at the N-terminus of the protein has been determined.

authors

  • RAMASAMY, R
  • SIMPSON, R
  • DEXTER, A
  • KEEGHAN, M
  • REED, C
  • BUSHELL, G
  • INGRAM, L
  • HENDERSON, T
  • MOLONEY, M
  • MORITZ, R

publication date

  • June 1988