Assessment of Temporal Heterogeneity and Regional Motion to Identify Wall Motion Abnormalities Using Treadmill Exercise Stress Three-Dimensional Echocardiography Academic Article uri icon


  • BACKGROUND: Exercise 3-dimensional echocardiography (3DE) may avoid the problem of poorly matched pre- and post-exercise 2-dimensional echocardiograms (2DE), and contraction front mapping (CFM) may be used to quantify the temporal homogeneity of contraction. We compared 3DE with 2DE for identification of angiographically significant disease. METHODS: Conventional 2DE and 3DE at rest and peak stress were performed in 110 patients (78 men, aged 60 +/- 11 years) who underwent angiography within 6 months. Offline assessment of CFM was performed qualitatively (delayed regional relaxation in a coronary territory) and quantitatively (difference in regional and global contraction delays from rest to peak in individual segments). The accuracy of each test was calculated for identification of 70% or more diameter angiographic stenoses. RESULTS: Patients were excluded for nondiagnostic stress (n = 12) or poor-quality 3DE (n = 8). Time until end of 2DE acquisition was 58 +/- 25 seconds, and time until end of 3DE (taken after 2DE) was 109 +/- 55 seconds. Receiver operating characteristic analyses were used to define normal cutoff ranges of contraction delays for the following coronary territories: left anterior descending (

publication date

  • March 2009