Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation Academic Article uri icon


  • We evaluated patients with end-stage heart failure who have a high likelihood of response to cardiac resynchronization therapy (biventricular pacing). It appears that 20% of patients do not respond to this expensive therapy despite the use of selection criteria (dilated cardiomyopathy, heart failure, New York Heart Association class II or IV, left ventricular ejection fraction <35%, left bundle branch block, and QRS >120 ms). The presence of left ventricular dyssynchrony is needed to result in improvement after cardiac resynchronization therapy.


  • Bax, Jeroen J
  • Marwick, Thomas H
  • Molhoek, Sander G
  • Bleeker, Gabe B
  • van Erven, Lieselot
  • Boersma, Eric
  • Steendijk, Paul
  • van der Wall, Ernst E
  • Schalij, Martin J

publication date

  • November 2003