Myocardial Strain Measurement With 2-Dimensional Speckle-Tracking Echocardiography Academic Article uri icon


  • The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.


  • Marwick, Thomas H
  • Leano, Rodel L
  • Brown, Joseph
  • Sun, Jing-Ping
  • Hoffmann, Rainer
  • Lysyansky, Peter
  • Becker, Michael
  • Thomas, James D

publication date

  • January 2009