Design of heterologous mitochondria: import of cattle cytochrome P-450SCC precursors in plant mitochondria Academic Article uri icon


  • It has been shown that pre-P-450scc of bovine adrenal cortex mitochondria synthesized in a rabbit reticulocyte lysate cell-free system, is translocated into isolated soybean cotyledon mitochondria, thereby taking the mature form size. This finding is suggestive of the occurrence of a specific receptor and maturase for pre-P-450scc in plant mitochondria. Thus, plant mitochondria can be used as recipients for the mammalian cholesterol hydroxylase system in an attempt to study the mechanism of its formation and preservation.


  • Luzikov, VN
  • Novikova, LA
  • Spiridonova, VA
  • Isaeva, LV
  • Whelan, J
  • Hugosson, M
  • Glaser, E

publication date

  • July 1, 1994