Design, synthesis and binding properties of a fluorescent α₉β₁/α₄β₁ integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells Academic Article uri icon

abstract

  • A fluorescent α9β1 integrin antagonist with nanomolar binding affinities has been demonstrated to bind bone marrow haemopoietic stem and progenitor cells in vivo.

authors

  • Cao, Benjamin
  • Hutt, Oliver E
  • Zhang, Zhen
  • Li, Songhui
  • Heazlewood, Shen Y
  • Williams, Brenda
  • Smith, Jessica A
  • Haylock, David N
  • Savage, G Paul
  • Nilsson, Susan K

publication date

  • 2014