Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans Academic Article uri icon

abstract

  • SCOPE:To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements in high-density lipoprotein (HDL) functions in high cardiovascular risk subjects. METHODS AND RESULTS:The association between 1-year changes in food group consumption and HDL functionality traits in 296 high cardiovascular risk subjects is assessed. Increases in virgin olive oil (10 g d-1 ) and whole grain consumption (25 g d-1 ) are associated with increments in cholesterol efflux capacity (+0.7%, P = 0.026, and +0.6%, P = 0.017, respectively). Increases in nut (30 g d-1 ) and legume intake (25 g d-1 ) are linked to increments in paraoxonase-1 activity (+12.2%, P = 0.049, and +11.7%, P = 0.043, respectively). Legume intake increases are also related to decreases in cholesteryl ester transfer protein activity (-4.8%, P = 0.028). Fish consumption increments (25 g d-1 ) are associated with increases in paraoxonase-1 activity (+3.9%, P = 0.030) and declines in cholesteryl ester transfer protein activity (-1.6%, P = 0.021), HDL cholesterol concentrations (-1.1%, P = 0.039), and functions related to HDL levels (cholesterol efflux capacity, -1.1%, P = 0.010). CONCLUSION:Increases in the consumption of virgin olive oil, nuts, legumes, whole grains, and fish (achievable through a regular diet) were associated with improvements in HDL functions in high cardiovascular risk subjects.

authors

  • Hernaez, Alvaro
  • Sanllorente, Albert
  • Castaner, Olga
  • Martinez-Gonzalez, Miguel A
  • Ros, Emilio
  • Pinto, Xavier
  • Estruch, Ramon
  • Salas-Salvado, Jordi
  • Corella, Dolores
  • Alonso-Gomez, Angel M
  • Serra-Majem, Lluis
  • Fiol, Miquel
  • Lapetra, Jose
  • Gomez-Gracia, Enrique
  • de la Torre, Rafael
  • Lamuela-Raventos, Rosa-Maria
  • Fito, Montserrat

publication date

  • 2019