Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment Academic Article uri icon

abstract

  • cIAPs keep RIP1 from getting to the DISC complex and complex II; when cIAPs are repressed, signaling is modulated by the cFLIP isoform.

authors

  • Geserick, Peter
  • Hupe, Mike
  • Moulin, Maryline
  • Wong, W Wei-Lynn
  • Feoktistova, Maria
  • Kellert, Beate
  • Gollnick, Harald
  • Silke, John
  • Leverkus, Martin

publication date

  • December 28, 2009

has subject area