Drug-resistant mutants of chinese hamster ovary cells possess an altered cell surface carbohydrate component Academic Article uri icon

abstract

  • Surface label experiments using the galactose oxidase-]3H]-borohydride technique reveal that cells from drug-resistant Chinese hamster ovary clones possess a surface carbohydrate component of apparent molecular weight 165,000 which is absent from wild-type cells. The component may also be demonstrated by [14C]glucosamine incorporation but not by [3H]leucine incorporation or by the lactoperoxidase surface labeling reaction.

publication date

  • 1976