Lack of association between genetic variations in the KALRN region and ischemic stroke Academic Article uri icon

abstract

  • OBJECTIVES: To investigate whether KALRN gene variation is associated with ischemic stroke (IS). DESIGN AND METHODS: Associations to overall IS and IS subtypes were investigated in SAHLSIS, which comprises 844 patients with IS and 668 controls. RESULTS: Associations between KALRN SNPs and overall IS and cardioembolic stroke were detected. Associations for overall IS were investigated in two additional Swedish samples, but could not be replicated. CONCLUSION: KALRN gene variation is not associated with overall IS.

authors

  • Olsson, Sandra
  • Jood, Katarina
  • Melander, Olle
  • Sjögren, Marketa
  • Norrving, Bo
  • Nilsson, Michael
  • Lindgren, Arne
  • Jern, Christina

publication date

  • August 2011