This randomized within-subject study investigated the effects of patellar tape on the onset of electromyographic (EMG) activity of vastus medialis obliquus (VMO) relative to vastus lateralis (VL), knee kinematics, and kinetics in 12 currently asymptomatic individuals with a VMO timing deficit and a history of patellofemoral pain. Participants were required to complete stair stepping and normal-pace and fast-pace walking tasks under three experimental conditions; no tape, control tape and therapeutic tape. EMG onsets of VMO and VL were measured by surface electrodes, stance phase knee flexion by the PEAK movement analysis system and vertical ground reaction force by a force plate. A two-way repeated measures analysis of variance showed that neither therapeutic tape nor control tape had any effect on the EMG VMO-VL onset timing difference. Therapeutic tape, but not control tape, led to significant increases in stance phase knee flexion. The first peak vertical ground reaction force was lowered by both control and therapeutic tape but only during fast walking. The results suggest that tape induced effects on neuromotor control of the vasti seen in other studies are related to reductions in pain rather than the presence of a baseline timing deficit. However, this cannot explain the improvements in stance phase knee flexion observed with tape.