Orthogonal strategy for the synthesis of dual-functionalised β3-peptide based hydrogels Academic Article uri icon

abstract

  • We describe a new class of hydrogelator based on helical β3-peptide foldamers carrying a bioactive payload. The β3-peptides self-assemble to form a nanofibrous mesh resulting in a stable hydrogel. Co-incubation with different β3-peptide monomers allowed tuning of cell adherence.

authors

  • Kulkarni, Ketav
  • Motamed, Sepideh
  • Habila, Nathan
  • Perlmutter, Patrick
  • Forsythe, John S
  • Aguilar, Marie-Isabel
  • Del Borgo, Mark P

publication date

  • 2016