OBJECTIVES:To examine the interrelationships between metacognitive skills and measures of emotional status and executive function following acquired brain injury (ABI), and examine their relative importance to psychosocial outcomes. DESIGN:A cross-sectional multicentre study employing correlational and multiple regression analyses. PARTICIPANTS:Sixty-seven adults with ABI living in the community, on average 4.4 years (SD = 4.7) postinjury. MEASURES:Sydney Psychosocial Reintegration Scale, Self-Awareness of Deficits Interview, Self-Regulation Skills Interview, Hospital Anxiety Depression Scale, Beck Hopelessness Scale, and standardized measures of executive function. RESULTS:Metacognitive skills correlated with level of hopelessness and executive measures of idea generation and error self-regulation. The best predictor of psychosocial outcome was depressive symptoms, with specific outcomes additionally related to error self-regulation and intellectual awareness. CONCLUSIONS:The findings highlight the need to evaluate interventions targeting depression and metacognitive skills to improve psychosocial outcomes.