Crystallization of an Lhx3–Isl1 complex Academic Article uri icon

abstract

  • A stable intramolecular complex comprising the LIM domains of the LIM-homeodomain protein Lhx3 tethered to a peptide region of Isl1 has been engineered, purified and crystallized. The monoclinic crystals belong to space group C2, with unit-cell parameters a = 119, b = 62.2, c = 51.9 A, beta = 91.6 degrees , and diffract to 2.05 A resolution.

authors

  • Bhati, Mugdha
  • Lee, Mihwa
  • Nancarrow, Amy Louise
  • Bach, Ingolf
  • Guss, J Mitchell
  • Matthews, Jacqueline Mary

publication date

  • April 1, 2008