Mapping of the chromosome 11 breakpoint of the t(4;11)(q21;p14–15) translocation Academic Article uri icon

abstract

  • We describe the localization of the chromosome 11 breakpoint of a T-ALL translocation, t(4;11)(q21;p14-15), to sub-band 11p15.5. The breakpoint is located between the genes for insulin-like growth factor II (IGFII) and the M1 subunit of ribonucleotide reductase (RRM1). This region does not include any previously cloned genes involved in cancer.

publication date

  • September 1993