Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk Academic Article uri icon

abstract

  • Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55–75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3–1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.

authors

  • Julibert, Alicia
  • Bibiloni, Maria
  • Bouzas, Cristina
  • Martinez-Gonzalez, Miguel
  • Salas-Salvadó, Jordi
  • Corella, Dolores
  • Zomeño, Maria
  • Romaguera, Dora
  • Vioque, Jesús
  • Alonso-Gómez, Ángel
  • Wärnberg, Julia
  • Martínez, J
  • Serra-Majem, Luís
  • Estruch, Ramon
  • Tinahones, Francisco
  • Lapetra, José
  • Pintó, Xavier
  • Lopez-Miranda, José
  • García-Molina, Laura
  • Gaforio, José
  • Matía-Martín, Pilar
  • Daimiel, Lidia
  • Martín-Sánchez, Vicente
  • Vidal, Josep
  • Vázquez, Clotilde
  • Ros, Emili
  • Toledo, Estefanía
  • Becerra-Tomás, Nerea
  • Pórtoles, Olga
  • Pérez-Vega, Karla
  • Fiol, Miquel
  • Torres-Collado, Laura
  • Tojal-Sierra, Lucas
  • Carabaño-Moral, Rosa
  • Abete, Itziar
  • Sanchez-Villegas, Almudena
  • Casas, Rosa
  • Bernal-López, María
  • Santos-Lozano, José
  • Galera, Ana
  • Ugarriza, Lucía
  • Ruiz-Canela, Miguel
  • Babio, Nancy
  • Coltell, Oscar
  • Schröder, Helmut
  • Konieczna, Jadwiga
  • Orozco-Beltrán, Domingo
  • Sorto-Sánchez, Carolina
  • Eguaras, Sonia
  • Barrubés, Laura
  • Fitó, Montserrat
  • Tur, Josep

publication date

  • 2019