Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea) Academic Article uri icon

abstract

  • A series of 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives were synthesized and evaluated for in vitro activity against the endoparasite Haemonchus contortus and the ectoparasite Ctenocephalides felis. Some compounds had significant in vitro activity against these parasites.

authors

  • Ali, Abdelselam
  • Bliese, Marianne
  • Rasmussen, Jo-Anne M
  • Sargent, Roger M
  • Saubern, Simon
  • Sawutz, David G
  • Wilkie, John S
  • Winkler, David A
  • Winzenberg, Kevin N
  • Woodgate, Ruth CJ

publication date

  • February 2007