Analysis of the minimal specificity of caspase 2 and identification of Ac-VDTTD-AFC as a caspase 2 selective peptide substrate Academic Article uri icon

abstract

  • The roles of the protease caspase-2 are currently poorly understood. Research into caspase-2 would benefit from more specific tools to monitor its activity. A more caspase-2-selective peptide, Ac-VDTTD-AFC, may help researchers to detect caspase-2 activity in cell extracts.

authors

  • Kitevska, T
  • Roberts, SJ
  • Pantaki-Eimany, D
  • Boyd, SE
  • Scott, FL
  • Hawkins, CJ

publication date

  • 2014