Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015: findings from the Global Burden of Disease 2015 study Academic Article uri icon

abstract

  • OBJECTIVES:We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. METHODS:We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. RESULTS:In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095-12,396,566) DALYs and 191,114 (95% UI 170,934-210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. CONCLUSIONS:Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.

authors

  • Mokdad, Ali H
  • Moradi-Lakeh, Maziar
  • El Bcheraoui, Charbel
  • Charara, Raghid
  • Khalil, Ibrahim
  • Afshin, Ashkan
  • Kassebaum, Nicholas J
  • Collison, Michael
  • Daoud, Farah
  • Chew, Adrienne
  • Krohn, Kristopher J
  • Colombara, Danny
  • Ehrenkranz, Rebecca
  • Foreman, Kyle J
  • Frostad, Joseph
  • Godwin, William W
  • Kutz, Michael
  • Rao, Puja C
  • Reiner, Robert
  • Troeger, Christopher
  • Wang, Haidong
  • Abajobir, Amanuel Alemu
  • Abbas, Kaja M
  • Abera, Semaw Ferede
  • Abu-Raddad, Laith J
  • Adane, Kelemework
  • Kiadaliri, Aliasghar Ahmad
  • Ahmadi, Alireza
  • Beshir, Muktar
  • Al-Eyadhy, Ayman
  • Alam, Khurshid
  • Alam, Noore
  • Alasfoor, Deena
  • Alizadeh-Navaei, Reza
  • Al-Maskari, Fatma
  • Al-Raddadi, Rajaa
  • Alsharif, Ubai
  • Altirkawi, Khalid A
  • Anber, Nahla
  • Ansari, Hossein
  • Antonio, Carl Abelardo T
  • Anwari, Palwasha
  • Asayesh, Hamid
  • Asgedom, Solomon Weldegebreal
  • Atey, Tesfay Mehari
  • Arthur, Euripide Frinel G
  • Bacha, Umar
  • Barac, Aleksandra
  • Bazargan-Hejazi, Shahrzad
  • Drew, Charles R
  • Geffen, David
  • Bedi, Neeraj
  • Bhutta, Zulfiqar A
  • Michael, Brauer
  • Butt, Zahid A
  • Castaneda-Orjuela, Carlos A
  • Danawi, Hadi
  • Djalalinia, Shirin
  • Endries, Aman Yesuf
  • Eshrati, Babak
  • Farvid, Maryam S
  • Fereshtehnejad, Seyed-Mohammad
  • Fischer, Florian
  • Garcia-Basteiro, Alberto L
  • Gebrehiwot, Kiros Tedla
  • Gebrehiwot, Tsegaye Tewelde
  • Hailu, Gessessew Bugssa
  • Hamadeh, Randah Ribhi
  • Hambisa, Mitiku Teshome
  • Hamidi, Samer
  • Hassanvand, Mohammad Sadegh
  • Hedayati, Mohammad T
  • Horita, Nobuyuki
  • Husseini, Abdullatif
  • Spencer, Lewis James
  • Javanbakht, Mehdi
  • Jonas, Jost B
  • Kasaeian, Amir
  • Khader, Yousef Saleh
  • Khan, Ejaz Ahmad
  • Khan, Gulfaraz
  • Khoja, Abdullah Tawfih Abdullah
  • Khubchandani, Jagdish
  • Kim, Yun Jin
  • Kissoon, Niranjan
  • Larson, Heidi J
  • Latif, Asma Abdul
  • Leshargie, Cheru Tesema
  • Lunevicius, Raimundas
  • Abd El Razek, Hassan Magdy
  • Abd El Razek, Mohammed Magdy
  • Majdzadeh, Reza
  • Majeed, Azeem
  • Malekzadeh, Reza
  • Farid, Habibolah Masoudi
  • Mehari, Alem
  • Memish, Ziad A
  • Mengistu, Desalegn Tadese
  • Mensah, George A
  • Mezgebe, Haftay Berhane
  • Nakamura, Sachiko
  • Oren, Eyal
  • Pourmalek, Farshad
  • Qorbani, Mostafa
  • Radfar, Amir
  • Rafay, Anwar
  • Vafa, Rahimi-Movaghar
  • Rai, Rajesh Kumar
  • Rawaf, David Laith
  • Rawaf, Salman
  • Refaat, Amany H
  • Rezaei, Satar
  • Rezai, Mohammad Sadegh
  • Roba, Hirbo Shore
  • Roshandel, Gholamreza
  • Safdarian, Mahdi
  • Safiri, Saeid
  • Sahraian, Mohammad Ali
  • Salamati, Payman
  • Samy, Abdallah M
  • Sartorius, Benn
  • Sepanlou, Sadaf G
  • Shaikh, Masood Ali
  • Shamsizadeh, Morteza
  • Shigematsu, Mika
  • Singh, Jasvinder A
  • Sufiyan, Muawiyyah Babale
  • Tehrani-Banihashemi, Arash
  • Temsah, Mohamad-Hani
  • Topor-Madry, Roman
  • Uthman, Olalekan A
  • Vollset, Stein Emil
  • Wakayo, Tolassa
  • Werdecker, Andrea
  • Wijeratne, Kulasekara M
  • Yaghoubi, Mohsen
  • Yimam, Hassen Hamid
  • Yonemoto, Naohiro
  • Younis, Mustafa Z
  • Zaki, Maysaa El Sayed
  • Jumaan, Aisha O
  • Vos, Theo
  • Naghavi, Mohsen
  • Hay, Simon I
  • Murray, Christopher JL

publication date

  • 2018