Tri-mean-based statistical differential gene expression detection Academic Article uri icon

abstract

  • Based on the assumption that only a subset of disease group has differential gene expression, traditional detection of differentially expressed genes is under the constraint that cancer genes are up- or down-regulated in all disease samples compared with normal samples. However, in 2005, Tomlins assumed and discussed the situation that only a subset of disease samples would be activated, which are often referred to as outliers.

authors

  • Ji, Zhaohua
  • Wu, Chunguo
  • Wang, Yao
  • Guan, Renchu
  • Tu, Huawei
  • Wu, Xiaozhou
  • Liang, Yanchun

publication date

  • 2012