This systematic review explores the health and well-being outcomes that families experience as a result of their participation in playgroups that provide health and well-being services. A systematic review of peer-reviewed literature resulted in 12 articles for inclusion. A meta-synthesis method, using reciprocal translation, was implemented to synthesize findings. Findings suggest that programs support children's social development, transition to school, and overall health. For parents, programs provide targeted social and health support, and knowledge sharing and learning opportunities. Future research in this area will benefit from participatory research approaches and exploring how universal approaches to program provision benefit families.