Association between diet quality indexes and the risk of short telomeres in an elderly population of the SUN project Academic Article uri icon

abstract

  • BACKGROUND:Shorter telomeres are associated with several age-related diseases, and lifestyle factors could influence this relationship. The aim of this study was to examine associations between salivary telomere length (TL) and diet quality using 5 evidence-based dietary indexes in an elderly (>55 years old) Spanish population of the SUN project (n = 886). METHOD:TL was measured using the quantitative real-time polymerase chain reaction. Age-adjusted TL variable through residuals methods was used for all analysis. Diet quality was assessed by the Prime Diet Quality Score (PDQS), Fat Quality Index (FQI), Mediterranean Diet Adherence Screener (MEDAS), Dietary Approaches to Stop Hypertension (DASH) index and the Alternative Healthy Eating Index (AHEI-2010). RESULTS:TL did differ according to sex, smoking status, and dyslipidemia in elderly subjects of the SUN study. In addition, subjects with dyslipidemia (compared to absence of dyslipidemia) had a significantly higher risk (27% vs. 18%, p = 0.015) of short telomeres (

authors

  • Ojeda-Rodríguez, Ana
  • Zazpe, Itziar
  • Alonso-Pedrero, Lucía
  • Zalba, Guillermo
  • Guillen-Grima, Francisco
  • Martinez-Gonzalez, Miguel A
  • Marti, Amelia

publication date

  • 2019